Patents by Inventor Rodrigo Morales

Rodrigo Morales has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic and diagnostics compositions targeting toll-like receptors and methods thereof
    Patent number: 11931400
    Abstract: Therapeutic compositions and an associated method for improving a Toll-like receptor (TLR)-related condition, including determining a set of peptide sequences associated with a microorganism-related modulator of a TLR, determining a first set of binding parameters for the set of peptide sequences in relation to the TLR, selecting a target subset of peptide sequences from the set of peptide sequences based on the first set of binding parameters, reengineering the target subset of peptide sequences based on mutating amino acid residues of the target subset of peptide sequences, determining a second set of binding parameters for the reengineered target subset of peptide sequences in relation to the TLR, and identifying a first peptide for use in a therapeutic composition for improving the TLR-related condition, based on the second set of binding parameters for the reengineered target subset of peptide sequences.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: March 19, 2024
    Assignee: PSOMAGEN, INC.
    Inventors: Zachary Apte, Jessica Richman, Daniel Almonacid, Melissa Alegria, Valeria Marquez, Eduardo Morales, Rodrigo Ortiz, Janet Torres, Paulo Covarrubias, Javier Gimpel, Ingrid Araya
  • Complement C2 Binding Proteins and Uses Thereof
    Publication number: 20220332804
    Abstract: The present disclosure relates to proteins comprising antigen binding sites that bind to human complement C2 (C2). The present disclosure also relates to methods of inhibiting complement activity in a subject as well as methods of treating or preventing complement-mediated disorders.
    Type: Application
    Filed: August 12, 2020
    Publication date: October 20, 2022
    Applicant: CSL Innovation Pty Ltd.
    Inventors: Matthew Hardy, Con Panousis, Rodrigo Morales
  • METHODS FOR ESTIMATING MISFOLDED PROTEIN CONCENTRATION IN FLUIDS AND TISSUE BY QUANTITATIVE PMCA
    Publication number: 20190137515
    Abstract: Described are methods for estimating misfolded protein concentration in fluids and tissues by quantitative PMCA.
    Type: Application
    Filed: December 27, 2018
    Publication date: May 9, 2019
    Inventors: Claudio Soto, Baian Chen, Rodrigo Morales
  • Methods for estimating prion concentration in fluids and tissue by quantitative PMCA
    Patent number: 10215763
    Abstract: The present embodiments disclose methods for estimating PrPSc concentration in fluids and tissues by quantitative PMCA.
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: February 26, 2019
    Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Claudio Soto, Baian Chen, Rodrigo Morales
  • METHODS FOR ESTIMATING PRION CONCENTRATION IN FLUIDS AND TISSUE BY QUANTITATIVE PMCA
    Publication number: 20110311997
    Abstract: The present embodiments disclose methods for estimating PrPSc concentration in fluids and tissues by quantitative PMCA.
    Type: Application
    Filed: May 18, 2011
    Publication date: December 22, 2011
    Inventors: Claudio Soto, Baian Chen, Rodrigo Morales
  • Apparatus and method for the non-chemical stabilization of bio-solids
    Publication number: 20060261013
    Abstract: An apparatus for treating an aqueous medium containing microorganisms comprises an intake for receiving the aqueous medium containing microorganisms. A pressure differential inducer is associated to the intake so as to receive the aqueous medium containing microorganisms with a desired level of gas saturation. The pressure differential inducer is actuatable to expose the aqueous medium containing microorganisms with a desired level of gas saturation to accelerations so as to cause cell wall rupture of the microorganisms. An outlet is associated with the pressure differential inducer for outletting the treated aqueous medium containing ruptured microorganism cells and contents. The treated aqueous medium containing ruptured cell wall of the microorganisms is disposed of and/or recycled.
    Type: Application
    Filed: May 17, 2006
    Publication date: November 23, 2006
    Inventors: Harold Haney, Robert Freeman, Rodrigo Morales, Daniel Gagnon