Abstract: Peptides derived from NKp44 protein, chimeric peptides, nucleotides encoding same and pharmaceutical compositions comprising same, are provided. Further, methods of extending the biological half-life of a protein of interest are provided.

Abstract: Peptides derived from NKp44 protein, chimeric peptides, nucleotides encoding same and pharmaceutical compositions comprising same, are provided. Further, methods of extending the biological half-life of a protein of interest are provided.

Abstract: Peptides derived from NKp44 protein, chimeric peptides, nucleotides encoding same and pharmaceutical compositions comprising same, are provided. Further, methods of extending the biological half-life of a protein of interest are provided.

Abstract: Peptides derived from NKp44 protein, chimeric peptides, nucleotides encoding same and pharmaceutical compositions comprising same, are provided. Further, methods of extending the biological half-life of a protein of interest are provided.

Abstract: Modified cells comprising a transmembrane polypeptide comprising at least one extracellular target receptor-binding domain, a transmembrane domain and an intracellular domain, wherein said intracellular domain is not capable of transducing any signal are provided. Methods of inducing or inhibiting signaling by a target receptor in a target cell comprising contacting the target cell with a modified cell of the invention are also provided.

Abstract: A device for administering injections includes a housing having an upper end, a lower end including a bottom surface with an injection needle opening, and an axis extending between the upper and lower ends. The device includes a needle housing with an injection needle. The needle housing is disposed within the housing for moving between a retracted position and an extended position. The device has an injection actuator for commencing an injection cycle including a first stage in which the needle housing and said plunger base are coupled together and move in a first direction along the axis and a second stage in which the needle housing and the plunger base are decoupled from one another so that the plunger base is free to move away from the needle housing in a second direction that is opposite the first direction.

Abstract: Compositions and methods of using cells derived from umbilical cord tissue, to stimulate and support angiogenesis, to improve blood flow, to regenerate, repair, and improve skeletal muscle damaged by a peripheral ischemic event, and to protect skeletal muscle from ischemic damage in peripheral vascular disease patients are disclosed. In particular, methods of treating a patient having a peripheral vascular disease by systemic administration of umbilical derived cells are disclosed.

Abstract: A device for administering injections includes a housing having an upper end, a lower end including a bottom surface with an injection needle opening, and an axis extending between the upper and lower ends. The device includes a needle housing with an injection needle. The needle housing is disposed within the housing for moving between a retracted position and an extended position. The device has an injection actuator for commencing an injection cycle including a first stage in which the needle housing and said plunger base are coupled together and move in a first direction along the axis and a second stage in which the needle housing and the plunger base are decoupled from one another so that the plunger base is free to move away from the needle housing in a second direction that is opposite the first direction.

Abstract: A device for administering injections includes a housing having an upper end, a lower end including a bottom surface with an injection needle opening, and an axis extending between the upper and lower ends. The device includes an injection needle disposed within the housing for moving between a retracted position and an extended position.

Abstract: Compositions and methods of using cells derived from umbilical cord tissue, to stimulate and support angiogenesis, to improve blood flow, to regenerate, repair, and improve skeletal muscle damaged by a peripheral ischemic event, and to protect skeletal muscle from ischemic damage in peripheral vascular disease patients are disclosed. In particular, methods of treating a patient having a peripheral vascular disease by systemic administration of umbilical derived cells are disclosed.

Abstract: The invention relates to an applicator tip for spraying and/or mixing at least two fluids that react together, the tip comprising: at least two fluid conduits for carrying the at least two fluids, each conduit having at least one outlet opening, the openings are positioned substantially on a same plane; at least two gas conduits for carrying a gas volume, each gas conduit comprises a proximal gas tube and a distal gas tube, each distal gas tube is bent as compared to the position of the proximal gas tube, and each distal gas tube has one gas opening positioned distal from the plane of the outlet openings; and a housing for accommodating the at least two fluid conduits and the at least two gas conduits. The device allows efficient spraying in close proximity to a surface.

Abstract: Compositions and methods of using cells derived from umbilical cord tissue, to stimulate and support angiogenesis, to improve blood flow, to regenerate, repair, and improve skeletal muscle damaged by a peripheral ischemic event, and to protect skeletal muscle from ischemic damage in peripheral vascular disease patients are disclosed. In particular, methods of treating a patient having a peripheral vascular disease with umbilical derived cells and fibrin glue are disclosed.

Abstract: Embodiments of the invention relates to decreasing effects of local and/or regional anesthesia by administering to a patient in need thereof an agent selected from the group of agents consisting of reactive nitrogen species (RNS), reactive oxygen species (ROS) and/or an agent which induces formation of RNS and/or ROS. Exemplary agents which may be used include peroxynitrite and hydrogen peroxide.

Abstract: The invention relates to a device for dispensing a fixed dose of fluid, the device comprising at least one barrel; at least one plunger at least partially enclosed within the barrel; a motion conversion mechanism for transferring actuated pressure force applied outside the barrel into movement of the at least one plunger in a dispensing direction, wherein the motion conversion mechanism comprises at least one rotating gear; and a releasing mechanism for disconnecting the plunger from the motion conversion mechanism, wherein at a released position the at least one plunger can move in a direction opposite to the dispensing direction, independent of a rotational movement of the at least one gear, and wherein the movement of the plunger in the opposite direction to the dispensing enables loading the fluid into the barrel.

Abstract: The invention relates to an applicator tip for spraying and/or mixing at least two fluids that react together, the tip comprising: at least two fluid conduits for carrying the at least two fluids, each conduit having at least one outlet opening, the openings are positioned substantially on a same plane; at least two gas conduits for carrying a gas volume, each gas conduit comprises a proximal gas tube and a distal gas tube, each distal gas tube is bent as compared to the position of the proximal gas tube, and each distal gas tube has one gas opening positioned distal from the plane of the outlet openings; and a housing for accommodating the at least two fluid conduits and the at least two gas conduits. The device allows efficient spraying in close proximity to a surface.

Abstract: Compositions and methods of using cells derived from umbilical cord tissue, to stimulate and support angiogenesis, to improve blood flow, to regenerate, repair, and improve skeletal muscle damaged by a peripheral ischemic event, and to protect skeletal muscle from ischemic damage in peripheral vascular disease patients are disclosed. In particular, methods of treating a patient having a peripheral vascular disease with umbilical derived cells and fibrin glue are disclosed.

Abstract: The invention relates to a device for dispensing a fixed dose of fluid, the device comprising at least one barrel; at least one plunger at least partially enclosed within the barrel; a motion conversion mechanism for transferring actuated pressure force applied outside the barrel into movement of the at least one plunger in a dispensing direction, wherein the motion conversion mechanism comprises at least one rotating gear; and a releasing mechanism for disconnecting the plunger from the motion conversion mechanism, wherein at a released position the at least one plunger can move in a direction opposite to the dispensing direction, independent of a rotational movement of the at least one gear, and wherein the movement of the plunger in the opposite direction to the dispensing enables loading the fluid into the barrel.

Abstract: The invention relates to a fibrin-based scaffold suitable for supporting a population of cells comprising mesenchymal stem cells (MSC) and/or umbilical tissue derived cells (UTC) at the site of administration for a prolonged period of time. The scaffold is capable of supporting at least 1×106 cells/ml scaffold. The invention also relates to the preparation of the scaffold and to its use. Preparation of the scaffold is carried out with a fibrinogen component comprising fibrinogen having a final concentration of higher than 17.5 mg/ml scaffold. The scaffold and the embedded MSC and/or UTC can be used for increasing vascularization and/or wound healing at the site of administration.

Abstract: A device for administering injections includes a housing having an upper end, a lower end including a bottom surface with an injection needle opening, and an axis extending between the upper and lower ends. The device includes an injection needle disposed within the housing for moving between a retracted position and an extended position.