Abstract: The present disclosure relates to the field of biochemistry, more particularly to detecting and measuring enzyme activity, even more particularly to detecting and measuring protease or nuclease activity. The means and methods disclosed in this application make use of Raman scattering, more particularly of surface enhanced Raman scattering (SERS). The disclosure discloses a carrier on which a monolayer of sequences containing a specific cleavage site is bound. The sequences comprise at least 2 Raman scatterers, one before and one behind the cleavage site, thereby providing an inherent control against ligand exchange.

Abstract: A sensor for sensing a substance such as for example glucose. The sensor is implantable in the body of a living creature. The sensor has a photonic integrated circuit, e.g. silicon-photonics integrated circuit, for spectrally processing radiation interacting with the sample. A continuous monitoring system can also include such a sensor.

Abstract: A sensor is described for sensing a substance such as for example glucose. The sensor is implantable in the body of a living creature. The sensor comprises a photonic integrated circuit, e.g. silicon-photonics, based radiation processor for spectrally processing radiation interacting with the sample. A continuous monitoring system also is described using such a sensor.

Abstract: The present invention relates to a coupler (100) for coupling radiation to one optical element. The coupler (100) comprises a splitter (110) for splitting a received radiation beam in at least two radiation sub-beams, at least two distinct sub-gratings (120a, 120b) adapted for directing radiation sub-beams such that all radiation is coupled out by the coupler into substantially one direction, and a means for guiding (130a, 130b) each of the radiation sub-beams between the splitter and a sub-grating (120a, 120b).

Abstract: A photonic integrated circuit (410) is described comprising at least one signal processing circuit (110). The signal processing circuit (110) comprises at least one input coupling element (120) for coupling incident light from a predetermined incoupling direction into the photonic integrated circuit (410), and at least one output coupling element (130) for coupling light out of the photonic integrated circuit (410) into an outcoupling direction. The relation between the incoupling direction and the outcoupling direction is different from a relation according to the law of reflection and the incoupling direction and the outcoupling direction are substantially the same. Furthermore, an optical sensor probe (400) comprising such a photonic integrated circuit (410) is disclosed.

Abstract: An optical device for optically multiplexing or demultiplexing light of different predetermined wavelengths is provided, the optical device comprising at least one first waveguide (11) and at least one second waveguide (12) formed on a substrate (10), wherein the at least one first waveguide and the at least one second waveguide intersect at an intersection, comprising a diffraction grating structure (13) formed at the intersection. There exists a first wavelength or wavelength band travelling within the first waveguide (11) exciting the grating structure and being diffracted an angle corresponding to an outcoupling direction and there exists a second wavelength or wavelength band, different from the first wavelength or wavelength band, travelling within the second waveguide (12) exciting the grating structure and being diffracted at an angle corresponding to the same outcoupling direction.

Abstract: A sensor is described for sensing a substance such as for example glucose. The sensor is implantable in the body of a living creature. The sensor comprises a photonic integrated circuit, e.g. silicon-photonics, based radiation processor for spectrally processing radiation interacting with the sample. A continuous monitoring system also is described using such a sensor.

Abstract: A photonic integrated circuit (410) is described comprising at least one signal processing circuit (110). The signal processing circuit (110) comprises at least one input coupling element (120) for coupling incident light from a predetermined incoupling direction into the photonic integrated circuit (410), and at least one output coupling element (130) for coupling light out of the photonic integrated circuit (410) into an outcoupling direction. The relation between the incoupling direction and the outcoupling direction is different from a relation according to the law of reflection and the incoupling direction and the outcoupling direction are substantially the same. Furthermore, an optical sensor probe (400) comprising such a photonic integrated circuit (410) is disclosed.

Abstract: The present invention relates to a coupler (100) for coupling radiation to one optical element. The coupler (100) comprises a splitter (110) for splitting a received radiation beam in at least two radiation sub-beams, at least two distinct sub-gratings (120a, 120b) adapted for directing radiation sub-beams such that all radiation is coupled out by the coupler into substantially one direction, and a means for guiding (130a, 130b) each of the radiation sub-beams between the splitter and a sub-grating (120a, 120b).

Abstract: An optical device for optically multiplexing or demultiplexing light of different predetermined wavelengths is provided, the optical device comprising at least one first waveguide (11) and at least one second waveguide (12) formed on a substrate (10), wherein the at least one first waveguide and the at least one second waveguide intersect at an intersection, comprising a diffraction grating structure (13) formed at the intersection. There exists a first wavelength or wavelength band travelling within the first waveguide (11) exciting the grating structure and being diffracted an angle corresponding to an outcoupling direction and there exists a second wavelength or wavelength band, different from the first wavelength or wavelength band, travelling within the second waveguide (12) exciting the grating structure and being diffracted at an angle corresponding to the same outcoupling direction.

Abstract: An optical detection system (100) for detecting biological, chemical or bio-chemical particles is described. The optical detection system (100) typically comprises a surface mode interference means. The surface mode interference means may comprise a layer (102) such as for example a metal layer like e.g. a gold layer. The surface mode interference means furthermore typically is adapted to create an interference effect between optical interface modes of the layer to detect optical changes in the vicinity of the layer (102). In this way, sample (106) occurring in the vicinity of the surface may be detected. The present invention furthermore relates to a method for performing optical detection and to a method for setting up an optical detection system wherein parameters are selected for tuning the surface mode interference means to a desired wavelength range and/or to a desired range of analyte refractive indices.

Abstract: An optical waveguide to fiber coupler comprises a substrate, a first waveguide and a second waveguide. The first and second waveguides are formed on the substrate and intersect at a right angle. A diffraction grating structure is formed at the intersection of the first and second waveguides, such that, when the coupler is physically abutted with a single mode optical fiber, in operation, a polarization split is obtained that couples orthogonal modes from the single-mode optical fiber into single identical modes in the first and second waveguides. Also, employing the coupler in optical polarization diverse applications provides for implementing a polarization insensitive photonic integrated circuit using such diffraction grating structures, such as, for example, photonic crystals.

Abstract: Alternative laser structures, which have potentially the same tuning performance as (S)SG-DBR and GCSR lasers, and a fabrication process which is similar to that of the (S)SG-DBR laser, are presented. The advantage of these structures is that the output power does not pass through a long passive region.

Abstract: Alternative laser structures, which have potentially the same tuning performance as (S)SG-DBR and GCSR lasers, and a fabrication process which is similar to that of the (S)SG-DBR laser, are presented. The advantage of these structures is that the output power does not pass through a long passive region.

Abstract: Alternative laser structures, which have potentially the same tuning performance as (S)SG-DBR and GCSR lasers, and a fabrication process which is similar to that of the (S)SG-DBR laser, are presented. The advantage of these structures is that the output power does not pass through a long passive region.

Abstract: A waveguide component has a slab waveguide, a rib waveguide, and a mode transition section where the rib waveguide and the slab waveguide are adjacent, and where the rib waveguide is tapered, to provide optical coupling, and lateral confinement rib waveguides are provided along the slab waveguide in the mode transition section to confine light from spreading laterally. The lateral confinement ribs can be formed in the same step with the same mask as used for the taper, to ensure alignment with the taper. They can be arranged either side of the taper. The lateral confinement ribs are significant for enabling a mode transition section which couples with low loss. In particular, it reduces the need for the taper to be so fine, or the taper to be made in both vertical and horizontal axes, both of which cause fabrication difficulties.

Abstract: An optical waveguide to fiber coupler comprises a substrate, a first waveguide and a second waveguide. The first and second waveguides are formed on the substrate and intersect at a right angle. A diffraction grating structure is formed at the intersection of the first and second waveguides, such that, when the coupler is physically abutted with a single mode optical fiber, in operation, a polarization split is obtained that couples orthogonal modes from the single-mode optical fiber into single identical modes in the first and second waveguides. Also, employing the coupler in optical polarization diverse applications provides for implementing a polarization insensitive photonic integrated circuit using such diffraction grating structures, such as, for example, photonic crystals.

Abstract: A system and method for guiding a beam of electromagnetic radiation is disclosed. The system includes at least a first stack of dielectric layers, the first stack comprising at least a first substack, a second substack and a third substack, the third substack separating said first and second substack, the first substack comprising at least one dielectric layer, the second substack comprises at least one dielectric layer, the third substack comprises at least one dielectric layer. The dielectric layers of the first substack and the second substack equidistant from the third substack have the same refractive index.

Abstract: A waveguide component has a slab waveguide, a rib waveguide, and a mode transition section where the rib waveguide and the slab waveguide are adjacent, and where the rib waveguide is tapered, to provide optical coupling, and lateral confinement rib waveguides are provided along the slab waveguide in the mode transition section to confine light from spreading laterally. The lateral confinement ribs can be formed in the same step with the same mask as used for the taper, to ensure alignment with the taper. They can be arranged either side of the taper. The lateral confinement ribs are significant for enabling a mode transition section which couples with low loss. In particular, it reduces the need for the taper to be so fine, or the taper to be made in both vertical and horizontal axes, both of which cause fabrication difficulties.

Abstract: An optical decision circuit, based on gain clamped semiconductor optical amplifiers, is disclosed. This optical decision circuit can be used for 2R signal regeneration in optical communication systems. By adding a clock signal to the input of said optical decision circuit, said circuit is also suited for 3R regeneration. Such a circuit can easily be implemented as an integrated circuit or an OEIC.