Patents by Inventor Roel Otto

Roel Otto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12031171
    Abstract: An antibacterial agent suppresses the growth of gram-positive contaminating bacteria. The antibacterial agent is selected from: a lactylate in accordance with the general formula (R—(O—CH(CH3)—CO)aO)bM; a glycerol ester in accordance with the general formula CH2OR1—CHOR2—CH2OR3; and, mixtures thereof. In the general formulae: R represents a C4-C18 acyl group, R1, R2 and R3 are each independently selected from H or a C4-C18 acyl group, the acyl group having an alkyl or alkenyl chain which may be branched or unbranched, with the proviso that at least one of R1, R2 or R3 is H and at least one of R1, R2, or R3 is an acyl group; M represents a proton (H+) or a counter-cation chosen from the group Li, Na, K, Ca, Mg, Zn, Fe(II), Cu, Mn, Ag, ammonium or substituted ammonium having one or more (C1-4)alkyl optionally substituted with one or more hydroxyl.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: July 9, 2024
    Assignee: PURAC BIOCHEM B.V.
    Inventors: Roel Otto, Aldana Mariel Ramirez, Jenny Eelderink
  • Publication number: 20190241916
    Abstract: An antibacterial agent suppresses the growth of gram-positive contaminating bacteria. The antibacterial agent is selected from: a lactylate in accordance with the general formula (R—(O—CH(CH3)—CO)aO)bM; a glycerol ester in accordance with the general formula CH2OR1—CHOR2—CH2OR3; and, mixtures thereof. In the general formulae: R represents a C4-C18 acyl group, R1, R2 and R3 are each independently selected from H or a C4-C18 acyl group, the acyl group having an alkyl or alkenyl chain which may be branched or unbranched, with the proviso that at least one of R1, R2 or R3 is H and at least one of R1, R2, or R3 is an acyl group; M represents a proton (H+) or a counter-cation chosen from the group Li, Na, K, Ca, Mg, Zn, Fe(II), Cu, Mn, Ag, ammonium or substituted ammonium having one or more (C1-4)alkyl optionally substituted with one or more hydroxyl.
    Type: Application
    Filed: September 5, 2017
    Publication date: August 8, 2019
    Applicant: PURAC BIOCHEM BV
    Inventors: Roel OTTO, Aldana Mariel RAMIREZ, Jenny EELDERINK
  • Patent number: 8329638
    Abstract: An antibacterial composition includes a combination of fatty acid ester of fatty acid and hydroxy carboxylic acid with an antibacterial agent selected from polylysine, chitosan, protamine, their salts and mixtures hereof. The hydroxy carboxylic acid may be present as acid in its free form, in its salt form and/or in its ester form. The composition may be used as an antibacterial agent against gram-negative bacteria in various products, applications and methods.
    Type: Grant
    Filed: May 24, 2011
    Date of Patent: December 11, 2012
    Assignee: Purac Biochem B.V.
    Inventors: Roel Otto, Aldana Mariel Ramirez, Diderik Reinder Kremer
  • Patent number: 8119376
    Abstract: The present invention pertains to a method for the production of lactic acid or a salt thereof wherein starch is subjected to a process of simultaneous saccharification and fermentation, the method comprising saccharifying starch in a medium comprising at least a glucoamylase and simultaneously fermenting the starch using a microorganism, and optionally isolating lactic acid from the medium, characterized in that a moderately thermophilic lactic acid-producing microorganism is used. The invention further relates to a method of performing said process in the presence of a moderately thermophilic lactic acid producing microorganism, which has been adapted to have its maximum performance at the working pH.
    Type: Grant
    Filed: May 13, 2003
    Date of Patent: February 21, 2012
    Assignee: Purac Biochem B.V.
    Inventor: Roel Otto
  • Publication number: 20110230395
    Abstract: An antibacterial composition includes a combination of fatty acid ester of fatty acid and hydroxy carboxylic acid with an antibacterial agent selected from polylysine, chitosan, protamine, their salts and mixtures hereof. The hydroxy carboxylic acid may be present as acid in its free form, in its salt form and/or in its ester form. The composition may be used as an antibacterial agent against gram-negative bacteria in various products, applications and methods.
    Type: Application
    Filed: May 24, 2011
    Publication date: September 22, 2011
    Applicant: PURAC BIOCHEM B.V.
    Inventors: Roel Otto, Aldana Mariel Ramirez, Diderik Reinder Kremer
  • Patent number: 7973006
    Abstract: The present invention relates to an antibacterial composition based on a combination of fatty acid ester of fatty acid and hydroxy carboxylic acid with an antibacterial agent selected from polylysine, protamine, their salts and mixtures hereof. The hydroxy carboxylic acid may be present as acid in its free form, in its salt form and/or in its ester form. The present invention further is directed to the use of said composition as antibacterial agent against gram-negative bacteria in various products, applications and methods. Furthermore, the present invention is related to products comprising said antibacterial agent.
    Type: Grant
    Filed: September 17, 2008
    Date of Patent: July 5, 2011
    Assignee: Purac Biochem B.V.
    Inventors: Roel Otto, Aldana Mariel Ramirez, Diderik Reinder Kremer
  • Publication number: 20090082443
    Abstract: The present invention relates to a method for the prevention and/or reduction of the presence, growth and/or activity of gram-negative bacteria comprising application of a composition comprising glycerol-based fatty acid esters and polylysine and/or salts of polylysine, wherein said glycerol-based fatty acid ester is used as antibacterial agent. The present invention further relates to the use of said composition as antibacterial agent in various products and applications ranging from technical products and personal-care products to food and drink products for animals and human consumption.
    Type: Application
    Filed: September 17, 2008
    Publication date: March 26, 2009
    Applicant: PURAC BIOCHEM B.V.
    Inventors: Roel Otto, Aldana Mariel Ramirez, Diderik Reinder Kremer
  • Publication number: 20090082253
    Abstract: The present invention relates to an antibacterial composition based on a combination of fatty acid ester of fatty acid and hydroxy carboxylic acid with an antibacterial agent selected from polylysine, protamine, their salts and mixtures hereof. The hydroxy carboxylic acid may be present as acid in its free form, in its salt form and/or in its ester form. The present invention further is directed to the use of said composition as antibacterial agent against gram-negative bacteria in various products, applications and methods. Furthermore, the present invention is related to products comprising said antibacterial agent.
    Type: Application
    Filed: September 17, 2008
    Publication date: March 26, 2009
    Applicant: PURAC BIOCHEM B.V.
    Inventors: Roel Otto, Aldana Mariel Ramirez, Diderik Reinder Kremer
  • Publication number: 20090074926
    Abstract: The present invention is directed to a method for preserving acidic beverages having a pH of or below 4.8 against fungi, yeasts and bacteria. Said preservation method comprises the application of a composition based on polylysine and/or a salt hereof in combination with a second preservative agent selected from glyceride and/or fatty acid ester of hydroxycarboxylic acid in its acidic, salt or ester form.
    Type: Application
    Filed: September 17, 2008
    Publication date: March 19, 2009
    Applicant: PURAC BIOCHEM B.V.
    Inventors: Roel Otto, Aldana M. Ramirez, Diderik R. Kremer, Elize W. Bontenbal
  • Publication number: 20080261285
    Abstract: The present invention pertains to a method for the production of lactic acid or a salt thereof wherein starch is subjected to a process of simultaneous saccharification and fermentation, the method comprising saccharifying starch in a medium comprising at least a glucoamylase and simultaneously fermenting the starch using a microorganism, and optionally isolating lactic acid from the medium, characterized in that a moderately thermophilic lactic acid-producing microorganism is used. The invention further relates to a method of performing said process in the presence of a moderately thermophilic lactic acid producing microorganism, which has been adapted to have its maximum performance at the working pH.
    Type: Application
    Filed: May 30, 2008
    Publication date: October 23, 2008
    Applicant: PURAC BIOCHEM B.V.
    Inventor: Roel Otto
  • Publication number: 20080261284
    Abstract: The present invention pertains to a method for the production of lactic acid or a salt thereof, wherein starch is subjected to a process of simultaneous saccharification and fermentation, the method comprising saccharifying starch in a medium comprising at least a glucoamylase and simultaneously fermenting the starch using a microorganism, and optionally isolating lactic acid from the medium, characterized in that a moderately thermophilic lactic acid-producing microorganism is used. The invention further relates to a method of performing said process in the presence of a moderately thermophilic lactic acid producing microorganism, which has been adapted to have its maximum performance at the working pH.
    Type: Application
    Filed: May 30, 2008
    Publication date: October 23, 2008
    Applicant: PURAC BIOCHEM B.V.
    Inventor: Roel Otto
  • Patent number: 7083955
    Abstract: Cost-effective processes for producing lactic acid and/or lactate from pentose-containing substrates, such as xylose-containing substrates, are provided. In particular, processes for producing lactic acid and/or lactate include fermentation of pentoses, such as xyloses, to enantiomerically pure lactic acid and/or lactate by moderately thermophilic Bacillus species. This fermentation runs by a homofermentive pathway and produces predominantly C3 compounds, so that C3 compounds can be recovered as lactic acid and/or lactate.
    Type: Grant
    Filed: January 13, 2004
    Date of Patent: August 1, 2006
    Assignee: Purac Biochem BV
    Inventor: Roel Otto
  • Publication number: 20050176120
    Abstract: The present invention pertains to a method for the production of lactic acid or a salt thereof wherein starch is subjected to a process of simultaneous saccharification and fermentation, the method comprising saccharifying starch in a medium comprising at least a glucoamylase and simultaneously fermenting the starch using a microorganism, and optionally isolating lactic acid from the medium, characterized in that a moderately thermophilic lactic acid-producing microorganism is used. The invention further relates to a method of performing said process in the presence of a moderately thermophilic lactic acid producing microorganism, which has been adapted to have its maximum performance at the working pH.
    Type: Application
    Filed: May 13, 2003
    Publication date: August 11, 2005
    Applicant: PURAC BIOCHEM B.V.
    Inventor: Roel Otto
  • Publication number: 20040203122
    Abstract: This invention relates to the production of lactic acid and/or lactate from pentose-containing substrate, particularly from xylose-containing substrate
    Type: Application
    Filed: January 13, 2004
    Publication date: October 14, 2004
    Applicant: Purac Biochem BV
    Inventor: Roel Otto