Abstract: The electronic device for sensing and/or actuating comprises a device surface to which an biological cell (40) is applied, further comprising a sensor and/or an actuator (25), and an access channel (20) with a channel port (21), said channel port being located in said surface. The access channel (20) is designed such that the biological cell (40) can enter the access channel (20) to thereby provide access to the sensor (25). Particularly the cell (40) forms a protruding portion (41) by entering the access channel (20), which portion is sensed. The access channel (20) may be provided with a specific sensor port at which the sensor (25) is present. The device may be used for sensing or actuating biological cells, such as neurons, for instance in electroporation treatments.

Abstract: Methods and devices for holographic imaging are disclosed. In some embodiments, a holographic imaging device is disclosed that includes at least one radiation source, a reflective surface, and an image sensor. The at least one radiation source may be configured to emit a radiation wave towards the reflective surface and an object positioned on or near the reflective surface, where the radiation wave is reflected by the reflective surface to produce a reference wave and is reflected directly toward the image sensor by the object to produce an object wave directed at the image sensor. Further, the image sensor may be configured to determine an interference pattern between the reference wave and the object wave. A holographic image representing the object may be reconstructed based on the interference pattern.

Abstract: A holographic imaging device for imaging an object under study includes a partially reflective surface having a contact side for contacting the object under study and an imaging side for partially reflecting a radiation wave. The device also includes at least one radiation source for projecting the radiation wave onto the imaging side of the partially reflective surface and an image sensor arranged to receive the radiation wave when reflected by the partially reflective surface. The image sensor is adapted for determining an interference pattern between the radiation wave reflected by the imaging side of the partially reflective surface and the radiation wave reflected by the object under study when contacting the contact side of the partially reflective surface.

Abstract: The present disclosure is related to an interface device for providing access to a network to be monitored. The interface device includes a plurality of elements, the elements being sensors and/or actuators. A selection circuit is provided for selecting a subset of elements among the plurality of elements, each element of the subset being arranged for outputting and/or receiving a signal. A local memory is provided for storing the subset.

Abstract: Methods and devices for holographic imaging are disclosed. In some embodiments, a holographic imaging device is disclosed that includes at least one radiation source, a reflective surface, and an image sensor. The at least one radiation source may be configured to emit a radiation wave towards the reflective surface and an object positioned on or near the reflective surface, where the radiation wave is reflected by the reflective surface to produce a reference wave and is reflected directly toward the image sensor by the object to produce an object wave directed at the image sensor. Further, the image sensor may be configured to determine an interference pattern between the reference wave and the object wave. A holographic image representing the object may be reconstructed based on the interference pattern.

Abstract: A holographic imaging device for imaging an object under study includes a partially reflective surface having a contact side for contacting the object under study and an imaging side for partially reflecting a radiation wave. The device also includes at least one radiation source for projecting the radiation wave onto the imaging side of the partially reflective surface and an image sensor arranged to receive the radiation wave when reflected by the partially reflective surface. The image sensor is adapted for determining an interference pattern between the radiation wave reflected by the imaging side of the partially reflective surface and the radiation wave reflected by the object under study when contacting the contact side of the partially reflective surface.

Abstract: The present invention provides an electronic device for sensing and/or actuating, the electronic device comprising at least one microneedle (10) on a substrate (1), each of the microneedles (10) comprising at least one channel (7, 8) surrounded by an insulating layer (6). The present invention also provides a method for making such an electronic device for sensing and/or actuating.

Abstract: The electronic device for sensing and/or actuating comprises a device surface to which an biological cell (40) is applied, further comprising a sensor and/or an actuator (25), and an access channel (20) with a channel port (21), said channel port being located in said surface. The access channel (20) is designed such that the biological cell (40) can enter the access channel (20) to thereby provide access to the sensor (25). Particularly the cell (40) forms a protruding portion (41) by entering the access channel (20), which portion is sensed. The access channel (20) may be provided with a specific sensor port at which the sensor (25) is present. The device may be used for sensing or actuating biological cells, such as neurons, for instance in electroporation treatments.

Abstract: A mixed micro-fluidic multi-electrode grid array (MEGA) device (10) suitable for holding a tissue slice (6) and for recording and/or stimulating neuron cells from said tissue slice (6), the MEGA device (10) comprising at least a top substrate in the form of a grid (4) comprising at least an electrical and/or optical multi-electrode array and a bottom substrate in the form of a stack made of a grid (1) comprising an electrical and/or optical multi-electrode array and a backbone (2) underneath said grid (1) comprising a micro-fluidic perfusion system. Furthermore said MEGA device (10) comprises means (5) for pressing and positioning said first and second substrate together and adhering a tissue slice in between said two substrates.

Abstract: A bio-hybrid implant suitable for recording and/or stimulating cells, the implant comprising (a) at least one closed insulated chamber (1) containing a substrate (502) with a neural interface (13) for connecting neurons to an electronic circuit, (b) at least one flexible guiding channel (10) having a first interface (11) to connect to at least one of the closed insulated chambers (1) and a second interface (9) to connect to a hosts' nerve system (7) or to another insulated chamber.

Abstract: The present disclosure is related to an interface device for providing access to a network to be monitored. The interface device includes a plurality of elements, the elements being sensors and/or actuators. A selection means is provided for selecting a subset of elements among the plurality of elements, each element of the subset being arranged for outputting and/or receiving a signal. A local memory is provided for storing the subset.

Abstract: The present invention provides an electronic device for sensing and/or actuating, the electronic device comprising at least one microneedle (10) on a substrate (1), each of the microneedles (10) comprising at least one channel (7, 8) surrounded by an insulating layer (6). The present invention also provides a method for making such an electronic device for sensing and/or actuating.