Patents by Inventor Roelof A. L. Bovenberg

Roelof A. L. Bovenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of homologous amdS genes as selectable markers
    Publication number: 20040005692
    Abstract: The present invention discloses novel amdS genes from fungi previously not known to contain and amdS gene, such as Aspergillus niger and Penicillium chrysogenum. The novel amdS genes can be used as homologous selectable marker genes in the transformation of these fungi. Alternatively, the cloned amdS genes can be used to inactivate the endogenous copy of the gene in order to reduce the background in transformation experiments.
    Type: Application
    Filed: January 17, 2003
    Publication date: January 8, 2004
    Inventors: Bart W. Swinkels, Gerardus C.M. Selten, Janna G. Bakhuis, Roelof A.L. Bovenberg, Adrianus W.H. Vollebregt
  • Use of homologous amdS genes as selectable markers
    Publication number: 20030124707
    Abstract: The present invention discloses novel amdS genes from fungi previously not known to contain and amdS gene, such as Aspergillus niger and Penicillium chrysogenum. The novel amdS genes can be used as homologous selectable marker genes in the transformation of these fungi. Alternatively, the cloned amdS genes can be used to inactivate the endogenous copy of the gene in order to reduce the background in transformation experiments.
    Type: Application
    Filed: August 1, 2002
    Publication date: July 3, 2003
    Inventors: Bart W. Swinkels, Gerardus C. M. Selten, Janna G. Bakhuis, Roelof A. L. Bovenberg, Adrianus W. H. Vollebregt
  • Polynucleotides encoding Aspergillus Niger and Penicillium Chrysogenum acetamidases and methods of use as selectable markers
    Patent number: 6548285
    Abstract: The present invention discloses novel amdS genes from fungi previously not known to contain an amdS gene, such as Aspergillus niger and Penicllium chrysogenum. The novel amdS genes can be used as homologous selectable marker genes in the transformation of these fungi. Alternatively, the cloned amdS genes can be used to inactivate the endogenous copy of the gene in order to reduce the background in transformation experiments.
    Type: Grant
    Filed: April 3, 1997
    Date of Patent: April 15, 2003
    Assignee: DSM N.V.
    Inventors: Bart W. Swinkels, Gerardus C. M. Selten, Janna G. Bakhuis, Roelof A. L. Bovenberg, Adrianus W. H. Vollebregt
  • Oxido reductase enzyme system obtained from P. chrysogenum
    Patent number: 5328839
    Abstract: A new oxido reductase enzyme activity obtainable from P. chrysogenum, involved in the production of .beta.-lactams, the set of genes encoding said enzyme activity, and a method to enhance said production by using the above-mentioned oxido reductase system and other oxido reductase systems or genes encoding for the same have been disclosed.
    Type: Grant
    Filed: March 24, 1992
    Date of Patent: July 12, 1994
    Assignee: Gist-Brocades
    Inventors: Yair Aharonowitz, Lucia H. M. van der Voort, Gerald Cohen, Roelof A. L. Bovenberg, Rachel Schreiber, Anat Argaman, Yossef Av-Gay, Helena M. Nan, Alfred Kattevilder, Harriet Palissa, Henk van Liempt