Abstract: Disclosed are compounds of the class of 2-phenylacetamides that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), and methods of using these modulators to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia.

Abstract: Disclosed are compounds that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), and methods of using these modulators to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia.

Abstract: Present invention refers to a method system and devices for managing user registration of a service in a IMS network. The proposed solution allows optimizing the dimensioning of networks focusing on active users.

Abstract: A method and a device are disclosed including a software or physical admission certificate configured to allow admission of a spectator to a special admission zone with a view to a performance stage for a predefined duration of time. The special admission zone is usable by multiple spectators in multiple successive time periods during the same performance. In various embodiments, the special admission zone is created by partitioning a general admission zone adjacent to the performance stage. In other embodiments, the special admission zone may be constructed as a “catwalk” around the stage to provide elevated viewing. In still other embodiments, the special admission zone may be formed near indoor or outdoor stages. In various embodiments, the admission certificate may be embodied in a computing device such as a smartphone, while in other embodiments the admission certificate may be in the form of a RFID equipped wristband.

Abstract: A system is provided for controlling admission to a special admission zone of a live performance event for a plurality of patrons. The special admission zone is separate and distinct from a general admission area of the event and has a fixed maximum capacity. The duration of the event is divided into a plurality of predefined time periods. The system includes a set of patron-issued wristbands containing electronically writeable and readable RFID chips. The RFID chips of each wristband are electronically encoded with a respective unique serial number that is electronically associated with one of the plurality of predefined time periods. A processor is programmed to verify when each patron in possession of a wristband requests entry to the special admission zone and to initiate transmission of event video or event still images to a social media site or event video to a web channel upon successful verification.

Abstract: The present invention relates to pharmaceutical compositions comprising furan-2-sulfonamide derivatives. The present invention further relates to methods of treatment of diseases or conditions associated with endothelial lipase activity, including coronary artery disease and low HDL-C.

Abstract: Present invention refers to a method, system and devices for managing user provisioning of a service in an IP Multimedia Subsystem (IMS) network. The proposed solution optimizes the dimensioning of Home subscriber server (HSS) according to active users.

Abstract: A method and system for managing calls in an IMS network, comprising a server and a device client communicated through an IP interface used for notifying, from the device client to the server, a decision selected by a user for managing an incoming call in a destination device where the device client runs. The server is where the network logic resides, interfacing with the IMS network via an ISC interface and with the device client via a Web Service or HTTP interface. The device client is where the user's decision logic resides as it comprises a user interface that provides the user with a set of available decisions for managing the incoming calls. The server, once notified on the decision selected by the user, releases the destination device from the call and takes an action based on said decision.

Abstract: A method and a device are disclosed including a software or physical admission certificate configured to allow admission of a spectator to a special admission zone with a view to a performance stage for a predefined duration of time. The special admission zone is usable by multiple spectators in multiple successive time periods during the same performance. In various embodiments, the special admission zone is created by partitioning a general admission zone adjacent to the performance stage. In other embodiments, the special admission zone may be constructed as a “catwalk” around the stage to provide elevated viewing. In still other embodiments, the special admission zone may be formed near indoor or outdoor stages. In various embodiments, the admission certificate may be embodied in a computing device such as a smartphone, while in other embodiments the admission certificate may be in the form of a RFID equipped wristband.

Abstract: Disclosed are compounds that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), and methods of using these modulators to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia.

Abstract: According the present invention there may be provided a method of determining which user device (UD) of a plurality of user devices should receive a Session Initiation Protocol, SIP, request (RQ) for a communication service on a telecommunications system, the system comprising: a plurality of user devices (UD) adapted to run a communication service; an application server (AS) in communication with the plurality of user devices on which there is comprised a registry of the plurality of user devices (UD), the registry comprising associations between user devices and SIP instances, each user device being associated with a respective user identity; and, a telecommunication network in communication with the plurality of user devices (UD) and with the application server (AS), wherein the method comprises, at the application server (AS): receiving a SIP request (RQ) for establishing a communication service, the SIP request intended for a user identity from the telecommunication network; and, dynamically determining

Abstract: Management of a call between a calling party that is a mobile terminal in a first cellular network and a called party that is a mobile terminal in a second cellular network is provided by: receiving at an Application Server, AS, of the first cellular network a request to establish a call with the called party from the calling party, the called party being identified in the indication by a circuit-switched identifier; identifying a registration for the called party in the first cellular network using the circuit-switched identifier for the called party, the registration providing a packet-switched identifier for the called party; and setting up a call between the calling party and the called party of the first cellular network by initiating a packet-switched connection from the AS in the first cellular network to the called party in the second cellular network using the packet-switched identifier for the called party.

Abstract: A method and a device are disclosed including a software or physical admission certificate configured to allow admission of a spectator to a special admission zone with a view to a performance stage for a predefined duration of time. The special admission zone is usable by multiple spectators in multiple successive time periods during the same performance. In various embodiments, the special admission zone is created by partitioning a general admission zone adjacent to the performance stage. In other embodiments, the special admission zone may be constructed as a “catwalk” around the stage to provide elevated viewing. In still other embodiments, the special admission zone may be formed near indoor or outdoor stages. In various embodiments, the admission certificate may be embodied in a computing device such as a smartphone, while in other embodiments the admission certificate may be in the form of a RFID equipped wristband.

Abstract: There is provided a method in a first communications device operable to communicate with a second device using a network supporting first and second different communication methods. The method comprises: allowing the first device to communicate with the second device using the first communication method; registering the first device on a service platform of the network; requesting from the service platform a second device status indicator of the ability of the second device to communicate using the second communication method; receiving the second device status indicator from the service platform; and, allowing the first device to communicate with the second device using the second communication method in dependence on the received second device status indicator. The second device status indicator depends on the current network connectivity of the second device. At least one of the first and second devices is a mobile telecommunications device.

Abstract: A method and apparatus for facilitating delivery of content over a telecommunication network is described. Specifically, the method comprises receiving content to be delivered from a first device associated with the network to at least one second device associated with the network, and triggering by a server a call (e.g.

Abstract: The present invention proposes a method and system which improves the assignment of resources in communication networks providing multimedia services, which allows offering different qualities of service to the users of an IMS network. To that end, a new node which controls signaling, routing and security for the operator according to the content of the session and the user is introduced in the method or system.

Abstract: A method and system for managing calls in an IMS network, comprising a server and a device client communicated through an IP interface used for notifying, from the device client to the server, a decision selected by a user for managing an incoming call in a destination device where the device client runs. The server is where the network logic resides, interfacing with the IMS network via an ISO interface and with the device client via a Web Service or HTTP interface. The device client is where the user's decision logic resides as it comprises a user interface that provides the user with a set of available decisions for managing the incoming calls. The server, once notified on the decision selected by the user, releases the destination device from the call and takes an action based on said decision.

Abstract: There is provided a method in a first communications device operable to communicate with a second device using a network supporting first and second different communication methods. The method comprises: allowing the first device to communicate with the second device using the first communication method; registering the first device on a service platform of the network; requesting from the service platform a second device status indicator of the ability of the second device to communicate using the second communication method; receiving the second device status indicator from the service platform; and, allowing the first device to communicate with the second device using the second communication method in dependence on the received second device status indicator. The second device status indicator depends on the current network connectivity of the second device. At least one of the first and second devices is a mobile telecommunications device.

Abstract: Method and apparatus for facilitating the set-up of a conference call over a telecommunication network, the call being between a first user and a one (or more) second user(s) of said network.

Abstract: There is provided a method in a first communications device operable to communicate with a second device using a network supporting first and second different communication methods. The method comprises: allowing the first device to communicate with the second device using the first communication method; registering the first device on a service platform of the network; requesting from the service platform a second device status indicator of the ability of the second device to communicate using the second communication method; receiving the second device status indicator from the service platform; and, allowing the first device to communicate with the second device using the second communication method in dependence on the received second device status indicator. The second device status indicator depends on the current network connectivity of the second device. At least one of the first and second devices is a mobile telecommunications device.