Patents by Inventor Roger A. Evans

Roger A. Evans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phenyl derivatives as cannabinoid receptor 2 agonists
    Patent number: 11339120
    Abstract: The invention relates to a compound of formula (I) wherein R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Grant
    Filed: July 15, 2020
    Date of Patent: May 24, 2022
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Olivier Gavelle, Uwe Grether, Matthias Nettekoven, Stephan Roever, Mark Rogers-Evans, Didier Rombach
  • PYRIDINE DERIVATIVES
    Publication number: 20220064178
    Abstract: The invention relates to compound of formula (I) wherein R1 to R3 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Application
    Filed: August 12, 2021
    Publication date: March 3, 2022
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Beat Frei, Luca Gobbi, Uwe Grether, Fabienne Ricklin, Stephan Roever, Mark Rogers-Evans, Didier Rombach
  • Pyridine derivatives
    Patent number: 11117903
    Abstract: The invention relates to compound of formula (I) wherein R1 to R3 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: September 14, 2021
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Beat Frei, Luca Gobbi, Uwe Grether, Fabienne Ricklin, Stephan Roever, Mark Rogers-Evans, Didier Rombach
  • PHENYL DERIVATIVES AS CANNABINOID RECEPTOR 2 AGONISTS
    Publication number: 20210171441
    Abstract: The invention relates to a compound of formula (I) wherein R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Application
    Filed: July 15, 2020
    Publication date: June 10, 2021
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Olivier Gavelle, Uwe Grether, Matthias Nettekoven, Stephan Roever, Mark Rogers-Evans, Didier Rombach
  • PUNCTURE DEVICE TO OPEN VACUUM JARS
    Publication number: 20210053810
    Abstract: The present invention provides a lid puncture device having a hemispheric main body, a resilient compressible component, a flexible magnetic disk, and a piercing pin. The hemispheric main body has a domed surface and a flat surface. The flat surface of the main body has a recessed region surrounding a central pillar. The resilient compressible component is housed within and attached to the recessed region of the hemispheric main body. The flexible magnetic disk is attached to the resilient compressible component. The piercing pin is attached to the hemispheric main body and held axially within the central pillar. A process of opening a vacuum-packed jar with the lid puncture device is also provided. The process includes placing the flexible magnetic disk of the lid puncture device onto a lid of the vacuum-packed jar and striking the domed surface.
    Type: Application
    Filed: August 13, 2020
    Publication date: February 25, 2021
    Inventor: Glen Roger Evans
  • Herbicidal compositions comprising isoxazolo[5,4-b]pyridines
    Patent number: 10881109
    Abstract: The present invention relates to herbicidal compositions comprising an isoxazolo[5,4-b]pyridine and at least one further compound selected from herbicidally active compounds and, if desired, safeners. The present invention also relates to the use of such a composition for controlling unwanted vegetation and to a method for controlling unwanted vegetation, which comprises allowing a composition to act on plants, their seeds and/or their habitat.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: January 5, 2021
    Assignee: BASF SE
    Inventors: Johannes Hutzler, Helmut Kraus, Anna Aleksandra Michrowska-Pianowska, Yogesh Oturkar, Trevor William Newton, Stefan Tresch, Jens Lerchl, Thomas Seitz, Richard Roger Evans, Klaus Kreuz, Ulrich Steinbrenner
  • Herbicidal compositions comprising isoxazolo[5,4-b]pyridines
    Patent number: 10881110
    Abstract: The present invention relates to herbicidal compositions comprising an isoxazolo[5,4-b]pyridine and at least one further compound selected from herbicidally active compounds and, if desired, safeners. The present invention also relates to the use of such a composition for controlling unwanted vegetation and to a method for controlling unwanted vegetation, which comprises allowing a composition to act on plants, their seeds and/or their habitat.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: January 5, 2021
    Assignee: BASF SE
    Inventors: Johannes Hutzler, Helmut Kraus, Anna Aleksandra Michrowska-Pianowska, Yogesh Oturkar, Trevor William Newton, Stefan Tresch, Jens Lerchl, Thomas Seitz, Richard Roger Evans, Klaus Kreuz, Ulrich Steinbrenner
  • Pyridyl-triazabicycles
    Patent number: 10829500
    Abstract: The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: November 10, 2020
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Bjoern Bartels, Cosimo Dolente, Wolfgang Guba, Wolfgang Haap, Andreas Kuglstatter, Ulrike Obst Sander, Jens-Uwe Peters, Mark Rogers-Evans, Thomas Woltering, Christian Schnider, Roger Wermuth
  • PYRIDINE DERIVATIVES
    Publication number: 20200239490
    Abstract: The invention relates to compound of formula (I) wherein R1 to R3 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Application
    Filed: December 20, 2019
    Publication date: July 30, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Beat Frei, Luca Gobbi, Uwe Grether, Fabienne Ricklin, Stephan Roever, Mark Rogers-Evans, Didier Rombach
  • OXADIAZOLE COMPOUNDS
    Publication number: 20200140400
    Abstract: The present invention relates to a compound of formula (I) or (II) or a stereoisomer, enantiomer, racemic, or tautomer thereof, (I) (II) wherein R1, R2, R3, L1, L2, L3, L4, L5 and n, have the same meaning as that defined in the claims and the description. The present invention also relates to compositions, in particular pharmaceuticals, comprising such compounds, and to uses of such compounds and compositions for the prevention and/or treatment of metabolic disorders and/or neurodegenerative diseases, an protein misfolding disorders.
    Type: Application
    Filed: January 2, 2020
    Publication date: May 7, 2020
    Applicant: REMYND NV
    Inventors: Gerard Griffioen, Bart De Taeye, Katrien Princen, Koen De Witte, Emilie Blanche, Hasane Ratni, Matthias Nettekoven, Mark Rogers-Evans
  • Oxadiazole compounds
    Patent number: 10562869
    Abstract: The present invention relates to a compound of formula (I) or (II) or a stereoisomer, enantiomer, racemic, or tautomer thereof, (I) (II) wherein R1, R2, R3, L1, L2, L3, L4, L5 and n, have the same meaning as that defined in the claims and the description. The present invention also relates to compositions, in particular pharmaceuticals, comprising such compounds, and to uses of such compounds and compositions for the prevention and/or treatment of metabolic disorders and/or neurodegenerative diseases, and/or protein misfolding disorders.
    Type: Grant
    Filed: March 17, 2015
    Date of Patent: February 18, 2020
    Assignee: REMYND NV
    Inventors: Gerard Griffioen, Bart De Taeye, Katrien Princen, Koen De Witte, Emilie Blanche, Hasane Ratni, Matthias Nettekoven, Mark Rogers-Evans
  • PYRIDYL-TRIAZABICYCLES
    Publication number: 20190352312
    Abstract: The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
    Type: Application
    Filed: July 31, 2019
    Publication date: November 21, 2019
    Inventors: Bjoern Bartels, Cosimo Dolente, Wolfgang Guba, Wolfgang Haap, Andreas Kuglstatter, Ulrike Obst Sander, Jens-Uwe Peters, Mark Rogers-Evans, Thomas Woltering, Christian Schnider, Roger Wermuth
  • Pyridyl-triazabicycles
    Patent number: 10414780
    Abstract: The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: September 17, 2019
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Bjoern Bartels, Cosimo Dolente, Wolfgang Guba, Wolfgang Haap, Andreas Kuglstatter, Ulrike Obst Sander, Jens-Uwe Peters, Mark Rogers-Evans, Thomas Woltering, Christian Schnider, Roger Wermuth
  • NOVEL PYRIDINE DERIVATIVES
    Publication number: 20190248803
    Abstract: The invention relates to a compound of formula (I) wherein A and R1 to R4 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Application
    Filed: April 24, 2019
    Publication date: August 15, 2019
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Olivier GAVELLE, Uwe Grether, Atsushi Kimbara, Matthias Nettekoven, Stephan Roever, Mark Rogers-Evans, Didier Rombach, Tanja Schulz-Gasch
  • Herbicidal isoxazolo[5,4-B]pyridines
    Patent number: 10334851
    Abstract: The invention relates to isoxazolo[5,4-b]pyridine compounds of formula I, to the agriculturally useful salts of isoxazolo[5,4-b]pyridine compounds of formula I, and to their use as herbicides.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: July 2, 2019
    Assignee: BASF SE
    Inventors: Anna Aleksandra Michrowska-Pianowska, Julia Major, Johannes Hutzler, Trevor William Newton, Richard Roger Evans, Klaus Kreuz, Klaus Grossmann, Dschun Song, Anja Simon, Matthias Witschel, William Karl Moberg, Liliana Parra Rapado, Tao Qu, Frank Stelzer, Helmut Kraus, Thomas Seitz, Andree van der Kloet, Ruediger Reingruber
  • Pyridine derivatives
    Patent number: 10308659
    Abstract: The invention relates to a compound of formula (I) wherein A and R1 to R4 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Grant
    Filed: September 28, 2015
    Date of Patent: June 4, 2019
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Olivier Gavelle, Uwe Grether, Atsushi Kimbara, Matthias Nettekoven, Roever Stephan, Mark Rogers-Evans, Didier Rombach, Tanja Schulz-Gasch
  • Herbicidal Compositions Comprising Isoxazolo[5,4-B]Pyridines
    Publication number: 20190150448
    Abstract: Herbicidal compositions comprising isoxazolo[5,4-b]pyridines The present invention relates to herbicidal compositions comprising an isoxazolo[5,4-b]pyridine and at least one further compound selected from herbicidally active compounds and, if desired, safeners. The present invention also relates to the use of such a composition for controlling unwanted vegetation and to a method for controlling unwanted vegetation, which comprises allowing a composition to act on plants, their seeds and/or their habitat.
    Type: Application
    Filed: January 18, 2019
    Publication date: May 23, 2019
    Inventors: Johannes HUTZLER, Helmut KRAUS, Anna Aleksandra MICHROWSKA-PIANOWSKA, Yogesh OTURKAR, Trevor William NEWTON, Stefan TRESCH, Jens LERCHL, Thomas SEITZ, Richard Roger EVANS, Klaus KREUZ, Ulrich STEINBRENNER
  • Herbicidal Compositions Comprising Isoxazolo[5,4-B]Pyridines
    Publication number: 20190150450
    Abstract: Herbicidal compositions comprising isoxazolo[5,4-b]pyridines The present invention relates to herbicidal compositions comprising an isoxazolo[5,4-b]pyridine and at least one further compound selected from herbicidally active compounds and, if desired, safeners. The present invention also relates to the use of such a composition for controlling unwanted vegetation and to a method for controlling unwanted vegetation, which comprises allowing a composition to act on plants, their seeds and/or their habitat.
    Type: Application
    Filed: January 18, 2019
    Publication date: May 23, 2019
    Inventors: Johannes HUTZLER, Helmut KRAUS, Anna Aleksandra MICHROWSKA-PIANOWSKA, Yogesh OTURKAR, Trevor William NEWTON, Stefan TRESCH, Jens LERCHL, Thomas SEITZ, Richard Roger EVANS, Klaus KREUZ, Ulrich STEINBRENNER
  • Herbicidal Compositions Comprising Isoxazolo[5,4-B]Pyridines
    Publication number: 20190150449
    Abstract: Herbicidal compositions comprising isoxazolo[5,4-b]pyridines The present invention relates to herbicidal compositions comprising an isoxazolo[5,4-b]pyridine and at least one further compound selected from herbicidally active compounds and, if desired, safeners. The present invention also relates to the use of such a composition for controlling unwanted vegetation and to a method for controlling unwanted vegetation, which comprises allowing a composition to act on plants, their seeds and/or their habitat.
    Type: Application
    Filed: January 18, 2019
    Publication date: May 23, 2019
    Inventors: Johannes HUTZLER, Helmut KRAUS, Anna Aleksandra MICHROWSKA-PIANOWSKA, Yogesh OTURKAR, Trevor William NEWTON, Stefan TRESCH, Jens LERCHL, Thomas SEITZ, Richard Roger EVANS, Klaus KREUZ, Ulrich STEINBRENNER
  • Radiolabeled cannabinoid receptor 2 ligand
    Patent number: 10227308
    Abstract: The present invention relates to a compound of formula (I) wherein R1 is defined as in the description and in the claims. The compound of formula (I) can be used as radiolabeled ligand.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: March 12, 2019
    Assignees: HOFFMANN-LA ROCHE INC., EIDGENÖSSISCHE TECHNISCHE HOCHSCHULE ZÜRCIH, UNIVERSITÄT ZÜRICH
    Inventors: Simon M. Ametamey, Juergen Fingerle, Luca Gobbi, Uwe Grether, Ahmed Haider, Thomas Hartung, Linjing Mu, Leo Nicholls, Mark Rogers-Evans, Christoph Ullmer