Patents by Inventor Roger A. Laine

Roger A. Laine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10575520
    Abstract: Compositions are described comprising an amount of a toxicant comprising a compound of the formula HNR1R2, or a salt thereof, wherein R1 and R2 are independently hydrogen, a substituted or unsubstituted C4-C6-cycloalkyl group or a substituted or unsubstituted C6-C12-aryl group; wherein the amount of the toxicant is sufficient to control termites. Methods for controlling termites using such compositions are also described.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: March 3, 2020
    Assignee: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
    Inventors: Roger A. Laine, Lucas Veillon, Gregg Henderson
  • Patent number: 10435344
    Abstract: An inexpensive, stereoselective synthesis for nootkatone, tetrahydronootkatone, and their derivatives is disclosed utilizing ozonolysis. The starting materials used in the synthesis are inexpensive and the reactions are commercially feasible and amenable to scaling up. The principal starting material, (?)-?-Pinene, is on the GRAS list (generally recognized as safe).
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: October 8, 2019
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: Roger Laine
  • Publication number: 20180362431
    Abstract: An inexpensive, stereoselective synthesis for nootkatone, tetrahydronootkatone, and their derivatives is disclosed utilizing ozonolysis. The starting materials used in the synthesis are inexpensive and the reactions are commercially feasible and amenable to scaling up. The principal starting material, (?)-?-Pinene, is on the GRAS list (generally recognized as safe).
    Type: Application
    Filed: December 8, 2016
    Publication date: December 20, 2018
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: Roger Laine
  • Publication number: 20170265464
    Abstract: Compositions are described comprising an amount of a toxicant comprising a compound of the formula HNR1R2, or a salt thereof, wherein R1 and R2 are independently hydrogen, a substituted or unsubstituted C4-C6-cycloalkyl group or a substituted or unsubstituted C6-C12-aryl group; wherein the amount of the toxicant is sufficient to control termites. Methods for controlling termites using such compositions are also described.
    Type: Application
    Filed: March 15, 2017
    Publication date: September 21, 2017
    Inventors: Roger A. Laine, Lucas Veillon, Gregg Henderson
  • Publication number: 20080206294
    Abstract: Several derivatives of naphthalene, including 1?-acetonaphthone, 2?-acetonaphthone, 1-methoxynaphthalene, and 2-methoxynaphthalene, were discovered to be effective toxicants and repellents of termites, and resulted in significant reduction in termite feeding activity. For example, 2?-acetonaphthone was found to be an effective repellent and feeding deterrent of termites. Termites exposed to concentrations as low as 8 mg/kg sand exhibited a significant reduction in tunneling and feeding activity. Moreover, some of the dead termites had symptoms indicative of a failure to molt. At concentrations ?20 ?g/cm2, 2?-acetonaphthone was a strong repellent. Interestingly, at 160-fold lower concentration (0.125 ?g/cm2), 2?-acetonaphthone stimulated termite feeding activity. As a sand barrier, 2?-acetonaphthone significantly inhibited tunneling and feeding activity in concentrations from 8.33 to 35.0 mg/kg. Molting problems were also identified in termites exposed to 2?-acetonaphthone.
    Type: Application
    Filed: February 1, 2008
    Publication date: August 28, 2008
    Inventors: Gregg Henderson, Sanaa A. Ibrahim, Rosemary Patton, Roger A. Laine, Betty C.R. Zhu, Feng Chen
  • Patent number: 7351744
    Abstract: Several derivatives of naphthalene, including 1?-acetonaphthone, 2?-acetpnaphthone, 1-methoxynaphthalene, and 2-methoxynaphthalene, were discovered to be effective toxicants and repellents of termites, and resulted in significant reduction in termite feeding activity. For example, 2?-acetonaphthone was found to be an effective repellent and feeding deterrent of termites. Termites exposed to concentrations as low as 8 mg/kg sand exhibited a significant reduction in tunneling and feeding activity. Moreover, some of the dead termites had symptoms indicative of a failure to molt. At concentrations ?20 ?g/cm2, 2?-acetonaphthone was a strong repellent. Interestingly, at 160-fold lower concentration (0.125 ?g/cm2), 2?-acetonaphthone stimulated termite feeding activity. As a sand barrier, 2?-acetonaphthone significantly inhibited tunneling and feeding activity in concentrations from 8.33 to 35.0 mg/kg. Molting problems were also identified in termites exposed to 2?-acetonaphthone.
    Type: Grant
    Filed: August 14, 2003
    Date of Patent: April 1, 2008
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Gregg Henderson, Sanaa A. Ibrahim, Rosemary Patton, Roger A. Laine, Betty C. R. Zhu, Feng Chen
  • Publication number: 20060235247
    Abstract: An inexpensive, stereoselective synthesis for nootkatone, tetrahydronootkatone, and their derivatives is disclosed. The starting materials used in the synthesis are inexpensive. The principal starting material, (?)-?-Pinene, is on the GRAS list (generally recognized as safe).
    Type: Application
    Filed: April 14, 2005
    Publication date: October 19, 2006
    Inventors: Anne Sauer, William Crowe, Roger Laine, Gregg Henderson
  • Patent number: 7112700
    Abstract: An inexpensive, stereoselective synthesis for nootkatone, tetrahydronootkatone, and their derivatives is disclosed. The starting materials used in the synthesis are inexpensive. The principal starting material, (?)-?-Pinene, is on the GRAS list (generally recognized as safe).
    Type: Grant
    Filed: April 14, 2005
    Date of Patent: September 26, 2006
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Anne M. Sauer, William E. Crowe, Roger A. Laine, Gregg Henderson
  • Publication number: 20050171213
    Abstract: Two derivatives of nootkatone, tetrahydronootkatone and 1,10-dihydronootkatone, are surprisingly effective as repellents of termites and mosquitos. Tetrahydronootkatone and 1,10-dihydronootkatone were shown to effectively repel termites at concentrations as low as 2 ?g/ml and 12.5 ?g/ml, respectively. Tetrahydronootkatone was shown to repel mosquitos at a concentration of 5%. Tetrahydronootkatone is an effective repellent of termites either by itself or as an addition to other substrates, including mulches made from wood products or other cellulose-containing material. Tetrahydronootkatone or 1,10-dihydronootkatone can be used to protect construction wood from attack by Formosan subterranean termites, either alone or used in combination with other compounds known to repel termites. It is also believed that these compounds will prove effective in repelling ants, ticks, and cockroaches. These derivatives of nootkatone are non-toxic to humans and other mammals and environmentally safe.
    Type: Application
    Filed: February 8, 2005
    Publication date: August 4, 2005
    Inventors: Betty Zhu, Gregg Henderson, Roger Laine
  • Patent number: 6906108
    Abstract: Extracts of vetiver oil were found to be significant repellents and toxicants of ants, ticks, and cockroaches. Nootkatone was shown to significantly decrease ant invasion and increase mortality in fire ants. Nootkatone is an effective repellent and toxicant of ants either by itself or as an addition to other substrates, including mulches made from vetiver grass roots, diatomaceous earth, alumina, silica, clays; building materials made from either aluminum or wood; and other suitable solid substances. Nootkatone was also a repellent and toxicant to ticks; and a repellent to cockroaches. Nootkatone is non-toxic to humans and other mammals and is environmentally safe. In addition, it is believed that other extracts of vetiver oil, specifically ?-cedrene, zizanol and bicyclovetivenol, will be effective against ants, ticks, and cockroaches.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: June 14, 2005
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Gregg Henderson, Donald O. Heumann, Roger A. Laine, Lara Maistrello, Betty C. R. Zhu, Feng Chen
  • Patent number: 6897244
    Abstract: Two derivatives of nootkatone, tetrahydronootkatone and 1,10-dihydronootkatone, are surprisingly effective as repellents of termites and mosquitos. Tetrahydronootkatone and 1,10-dihydronootkatone were shown to effectively repel termites at concentrations as low as 2 ?g/ml and 12.5 ?g/ml, respectively. Tetrahydronootkatone was shown to repel mosquitos at a concentration of 5%. Tetrahydronootkatone is an effective repellent of termites either by itself or as an addition to other substrates, including mulches made from wood products or other cellulose-containing material. Tetrahydronootkatone or 1,10-dihydronootkatone can be used to protect construction wood from attack by Formosan subterranean termites, either alone or used in combination with other compounds known to repel termites. It is also believed that these compounds will prove effective in repelling ants, ticks, and cockroaches. These derivatives of nootkatone are non-toxic to humans and other mammals and environmentally safe.
    Type: Grant
    Filed: July 3, 2002
    Date of Patent: May 24, 2005
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Betty C. R. Zhu, Gregg Henderson, Roger A. Laine
  • Patent number: 6890960
    Abstract: Extracts of vetiver oil were found to significantly repel termites. In one extract, nootkatone was isolated and found to be a significant repellent and toxicant of termites. Nootkatone significantly decreased food consumption, decreased tunneling behavior, and increased mortality in termites. Nootkatone is an effective repellent and toxicant of termites either by itself or as an addition to other materials or substrates, including mulches made from vetiver grass roots or other wood products. Nootkatone can also be used to protect construction wood from attack by Formosan subterranean termites. Nootkatone as a repellent is non-toxic to humans and other mammals and is environmentally safe. In addition, ?-cedrene was found to be a weak termite repellent; and both zizanol and bicyclovetivenol were found to be repellents and toxicants of termites.
    Type: Grant
    Filed: October 18, 2000
    Date of Patent: May 10, 2005
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Gregg Henderson, Roger A. Laine, Donald O. Heumann, Feng Chen, Betty C. R. Zhu
  • Publication number: 20050037045
    Abstract: Several derivatives of naphthalene, including 1?-acetonaphthone, 2?-acetpnaphthone, 1-methoxynaphthalene, and 2-methoxynaphthalene, were discovered to be effective toxicants and repellents of termites, and resulted in significant reduction in termite feeding activity. For example, 2?-acetonaphthone was found to be an effective repellent and feeding deterrent of termites. Termites exposed to concentrations as low as 8 mg/kg sand exhibited a significant reduction in tunneling and feeding activity. Moreover, some of the dead termites had symptoms indicative of a failure to molt. At concentrations ?20 ?g/cm2, 2?-acetonaphthone was a strong repellent. Interestingly, at 160-fold lower concentration (0.125 ?g/cm2), 2?-acetonaphthone stimulated termite feeding activity. As a sand barrier, 2?-acetonaphthone significantly inhibited tunneling and feeding activity in concentrations from 8.33 to 35.0 mg/kg. Molting problems were also identified in termites exposed to 2?-acetonaphthone.
    Type: Application
    Filed: August 14, 2003
    Publication date: February 17, 2005
    Inventors: Gregg Henderson, Sanaa Ibrahim, Rosemary Patton, Roger Laine, Betty Zhu, Feng Chen
  • Publication number: 20040157935
    Abstract: Extracts of vetiver oil were found to be significant repellents and toxicants of ants, ticks, and cockroaches. Nootkatone was shown to significantly decrease ant invasion and increase mortality in fire ants. Nootkatone is an effective repellent and toxicant of ants either by itself or as an addition to other substrates, including mulches made from vetiver grass roots, diatomaceous earth, alumina, silica, clays; building materials made from either aluminum or wood; and other suitable solid substances. Nootkatone was also a repellent and toxicant to ticks; and a repellent to cockroaches. Nootkatone is non-toxic to humans and other mammals and is environmentally safe. In addition, it is believed that other extracts of vetiver oil, specifically &agr;-cedrene, zizanol and bicyclovetivenol, will be effective against ants, ticks, and cockroaches.
    Type: Application
    Filed: February 2, 2004
    Publication date: August 12, 2004
    Inventors: Gregg Henderson, Donald O. Heumann, Roger A. Laine, Lara Maistrello, Betty C.R. Zhu, Feng Chen
  • Publication number: 20040005343
    Abstract: Two derivatives of nootkatone, tetrahydronootkatone and 1,10-dihydronootkatone, are surprisingly effective as repellents of termites and mosquitos. Tetrahydronootkatone and 1,10-dihydronootkatone were shown to effectively repel termites at concentrations as low as 2 &mgr;g/ml and 12.5 &mgr;g/ml, respectively. Tetrahydronootkatone was shown to repel mosquitos at a concentration of 5%. Tetrahydronootkatone is an effective repellent of termites either by itself or as an addition to other substrates, including mulches made from wood products or other cellulose-containing material. Tetrahydronootkatone or 1,10-dihydronootkatone can be used to protect construction wood from attack by Formosan subterranean termites, either alone or used in combination with other compounds known to repel termites. It is also believed that these compounds will prove effective in repelling ants, ticks, and cockroaches. These derivatives of nootkatone are non-toxic to humans and other mammals and environmentally safe.
    Type: Application
    Filed: July 3, 2002
    Publication date: January 8, 2004
    Inventors: Betty C. R. Zhu, Gregg Henderson, Roger A. Laine
  • Publication number: 20030073748
    Abstract: Extracts of vetiver oil were found to be significant repellents and toxicants of ants, ticks, and cockroaches. Nootkatone was shown to significantly decrease ant invasion and increase mortality in fire ants. Nootkatone is an effective repellent and toxicant of ants either by itself or as an addition to other substrates, including mulches made from vetiver grass roots, diatomaceous earth, alumina, silica, clays; building materials made from either aluminum or wood; and other suitable solid substances. Nootkatone was also a repellent and toxicant to ticks; and a repellent to cockroaches. Nootkatone is non-toxic to humans and other mammals and is environmentally safe. In addition, it is believed that other extracts of vetiver oil, specifically &agr;-cedrene, zizanol and bicyclovetivenol, will be effective against ants, ticks, and cockroaches.
    Type: Application
    Filed: August 17, 2001
    Publication date: April 17, 2003
    Inventors: Gregg Henderson, Donald O. Heumann, Roger A. Laine, Lara Maistrello, Betty C.R. Zhu, Feng Chen
  • Patent number: 6352703
    Abstract: Significant concentrations of naphthalene were detected in carton nests of Formosan subterranean termites, Coptotermes formosanus Shiraki, collected from Florida, Hawaii, and Louisiana. This is the first report of naphthalene being associated with termites or any other insects. Naphthalene and other compounds associated with termite carton nests may be used to increase termite bait acceptance. New attractant molecules include 2-phenoxyethanol. New feeding stimulants include ergosterol. A list of volatile compounds associated with termite nests is presented, compounds that may be used to detect termite nests.
    Type: Grant
    Filed: June 7, 2000
    Date of Patent: March 5, 2002
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Gregg Henderson, Jian Chen, Roger A. Laine
  • Patent number: 6184027
    Abstract: Catalytically inactive murein binding enzyme diagnostic reagents and methods and kits for detecting eubacteria and fungus in biological samples.
    Type: Grant
    Filed: March 4, 1999
    Date of Patent: February 6, 2001
    Assignees: Anomeric, Inc., Board of Supervisors Louisiana State University
    Inventors: Roger A. Laine, Wai Chun.Jennifer Lo
  • Patent number: 6159719
    Abstract: Murein binding polypeptide and antibiotic diagnostic reagents, methods and kits for detecting eubacteria and fungus in biological samples.
    Type: Grant
    Filed: March 3, 1999
    Date of Patent: December 12, 2000
    Assignees: Anomeri, Inc., Board of Supervisors Louisiana State University
    Inventors: Roger A. Laine, Wai Chun Jennifer Lo
  • Patent number: 6121420
    Abstract: A 134 kDa, calcium-independent, chitin-binding lectin called chitovibrin is secreted by marine bacteria of the genus Vibnio. The secretion of chitovibrin is inducible by chitin or chitin-oligomers. Chitovibrin shows no apparent enzymatic activity, but has a strong affinity for chitin and for chito-oligomers dp9 and larger. The protein has an isoelectric pH of 3.6, shows thermal tolerance, binds chitin with an optimum at pH 6 and is active in 0-4 M NaCl. Chitovibrin is useful as a stain for fungi and other chitin-containing organisms. Chitovibrin may be used to detect the presence of chitin, particularly in diagnosing fungal infections in humans, animals, and plant materials. Fungal infections are a particular problem in immunocompromised hosts such as AIDS patients and bone marrow transplant patients, because they can cause opportunistic infections. The chitovibrin diagnostic method allows the convenient, broad spectrum diagnosis of fungal infections in tissue samples or in body fluids.
    Type: Grant
    Filed: April 13, 1999
    Date of Patent: September 19, 2000
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: Roger A. Laine