Patents by Inventor Roger A. Laine
Roger A. Laine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10575520Abstract: Compositions are described comprising an amount of a toxicant comprising a compound of the formula HNR1R2, or a salt thereof, wherein R1 and R2 are independently hydrogen, a substituted or unsubstituted C4-C6-cycloalkyl group or a substituted or unsubstituted C6-C12-aryl group; wherein the amount of the toxicant is sufficient to control termites. Methods for controlling termites using such compositions are also described.Type: GrantFiled: March 15, 2017Date of Patent: March 3, 2020Assignee: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGEInventors: Roger A. Laine, Lucas Veillon, Gregg Henderson
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Patent number: 10435344Abstract: An inexpensive, stereoselective synthesis for nootkatone, tetrahydronootkatone, and their derivatives is disclosed utilizing ozonolysis. The starting materials used in the synthesis are inexpensive and the reactions are commercially feasible and amenable to scaling up. The principal starting material, (?)-?-Pinene, is on the GRAS list (generally recognized as safe).Type: GrantFiled: December 8, 2016Date of Patent: October 8, 2019Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical CollegeInventor: Roger Laine
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Publication number: 20180362431Abstract: An inexpensive, stereoselective synthesis for nootkatone, tetrahydronootkatone, and their derivatives is disclosed utilizing ozonolysis. The starting materials used in the synthesis are inexpensive and the reactions are commercially feasible and amenable to scaling up. The principal starting material, (?)-?-Pinene, is on the GRAS list (generally recognized as safe).Type: ApplicationFiled: December 8, 2016Publication date: December 20, 2018Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical CollegeInventor: Roger Laine
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Publication number: 20170265464Abstract: Compositions are described comprising an amount of a toxicant comprising a compound of the formula HNR1R2, or a salt thereof, wherein R1 and R2 are independently hydrogen, a substituted or unsubstituted C4-C6-cycloalkyl group or a substituted or unsubstituted C6-C12-aryl group; wherein the amount of the toxicant is sufficient to control termites. Methods for controlling termites using such compositions are also described.Type: ApplicationFiled: March 15, 2017Publication date: September 21, 2017Inventors: Roger A. Laine, Lucas Veillon, Gregg Henderson
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Publication number: 20080206294Abstract: Several derivatives of naphthalene, including 1?-acetonaphthone, 2?-acetonaphthone, 1-methoxynaphthalene, and 2-methoxynaphthalene, were discovered to be effective toxicants and repellents of termites, and resulted in significant reduction in termite feeding activity. For example, 2?-acetonaphthone was found to be an effective repellent and feeding deterrent of termites. Termites exposed to concentrations as low as 8 mg/kg sand exhibited a significant reduction in tunneling and feeding activity. Moreover, some of the dead termites had symptoms indicative of a failure to molt. At concentrations ?20 ?g/cm2, 2?-acetonaphthone was a strong repellent. Interestingly, at 160-fold lower concentration (0.125 ?g/cm2), 2?-acetonaphthone stimulated termite feeding activity. As a sand barrier, 2?-acetonaphthone significantly inhibited tunneling and feeding activity in concentrations from 8.33 to 35.0 mg/kg. Molting problems were also identified in termites exposed to 2?-acetonaphthone.Type: ApplicationFiled: February 1, 2008Publication date: August 28, 2008Inventors: Gregg Henderson, Sanaa A. Ibrahim, Rosemary Patton, Roger A. Laine, Betty C.R. Zhu, Feng Chen
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Patent number: 7351744Abstract: Several derivatives of naphthalene, including 1?-acetonaphthone, 2?-acetpnaphthone, 1-methoxynaphthalene, and 2-methoxynaphthalene, were discovered to be effective toxicants and repellents of termites, and resulted in significant reduction in termite feeding activity. For example, 2?-acetonaphthone was found to be an effective repellent and feeding deterrent of termites. Termites exposed to concentrations as low as 8 mg/kg sand exhibited a significant reduction in tunneling and feeding activity. Moreover, some of the dead termites had symptoms indicative of a failure to molt. At concentrations ?20 ?g/cm2, 2?-acetonaphthone was a strong repellent. Interestingly, at 160-fold lower concentration (0.125 ?g/cm2), 2?-acetonaphthone stimulated termite feeding activity. As a sand barrier, 2?-acetonaphthone significantly inhibited tunneling and feeding activity in concentrations from 8.33 to 35.0 mg/kg. Molting problems were also identified in termites exposed to 2?-acetonaphthone.Type: GrantFiled: August 14, 2003Date of Patent: April 1, 2008Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical CollegeInventors: Gregg Henderson, Sanaa A. Ibrahim, Rosemary Patton, Roger A. Laine, Betty C. R. Zhu, Feng Chen
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Publication number: 20060235247Abstract: An inexpensive, stereoselective synthesis for nootkatone, tetrahydronootkatone, and their derivatives is disclosed. The starting materials used in the synthesis are inexpensive. The principal starting material, (?)-?-Pinene, is on the GRAS list (generally recognized as safe).Type: ApplicationFiled: April 14, 2005Publication date: October 19, 2006Inventors: Anne Sauer, William Crowe, Roger Laine, Gregg Henderson
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Patent number: 7112700Abstract: An inexpensive, stereoselective synthesis for nootkatone, tetrahydronootkatone, and their derivatives is disclosed. The starting materials used in the synthesis are inexpensive. The principal starting material, (?)-?-Pinene, is on the GRAS list (generally recognized as safe).Type: GrantFiled: April 14, 2005Date of Patent: September 26, 2006Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical CollegeInventors: Anne M. Sauer, William E. Crowe, Roger A. Laine, Gregg Henderson
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Publication number: 20050171213Abstract: Two derivatives of nootkatone, tetrahydronootkatone and 1,10-dihydronootkatone, are surprisingly effective as repellents of termites and mosquitos. Tetrahydronootkatone and 1,10-dihydronootkatone were shown to effectively repel termites at concentrations as low as 2 ?g/ml and 12.5 ?g/ml, respectively. Tetrahydronootkatone was shown to repel mosquitos at a concentration of 5%. Tetrahydronootkatone is an effective repellent of termites either by itself or as an addition to other substrates, including mulches made from wood products or other cellulose-containing material. Tetrahydronootkatone or 1,10-dihydronootkatone can be used to protect construction wood from attack by Formosan subterranean termites, either alone or used in combination with other compounds known to repel termites. It is also believed that these compounds will prove effective in repelling ants, ticks, and cockroaches. These derivatives of nootkatone are non-toxic to humans and other mammals and environmentally safe.Type: ApplicationFiled: February 8, 2005Publication date: August 4, 2005Inventors: Betty Zhu, Gregg Henderson, Roger Laine
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Patent number: 6906108Abstract: Extracts of vetiver oil were found to be significant repellents and toxicants of ants, ticks, and cockroaches. Nootkatone was shown to significantly decrease ant invasion and increase mortality in fire ants. Nootkatone is an effective repellent and toxicant of ants either by itself or as an addition to other substrates, including mulches made from vetiver grass roots, diatomaceous earth, alumina, silica, clays; building materials made from either aluminum or wood; and other suitable solid substances. Nootkatone was also a repellent and toxicant to ticks; and a repellent to cockroaches. Nootkatone is non-toxic to humans and other mammals and is environmentally safe. In addition, it is believed that other extracts of vetiver oil, specifically ?-cedrene, zizanol and bicyclovetivenol, will be effective against ants, ticks, and cockroaches.Type: GrantFiled: August 17, 2001Date of Patent: June 14, 2005Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical CollegeInventors: Gregg Henderson, Donald O. Heumann, Roger A. Laine, Lara Maistrello, Betty C. R. Zhu, Feng Chen
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Patent number: 6897244Abstract: Two derivatives of nootkatone, tetrahydronootkatone and 1,10-dihydronootkatone, are surprisingly effective as repellents of termites and mosquitos. Tetrahydronootkatone and 1,10-dihydronootkatone were shown to effectively repel termites at concentrations as low as 2 ?g/ml and 12.5 ?g/ml, respectively. Tetrahydronootkatone was shown to repel mosquitos at a concentration of 5%. Tetrahydronootkatone is an effective repellent of termites either by itself or as an addition to other substrates, including mulches made from wood products or other cellulose-containing material. Tetrahydronootkatone or 1,10-dihydronootkatone can be used to protect construction wood from attack by Formosan subterranean termites, either alone or used in combination with other compounds known to repel termites. It is also believed that these compounds will prove effective in repelling ants, ticks, and cockroaches. These derivatives of nootkatone are non-toxic to humans and other mammals and environmentally safe.Type: GrantFiled: July 3, 2002Date of Patent: May 24, 2005Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical CollegeInventors: Betty C. R. Zhu, Gregg Henderson, Roger A. Laine
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Patent number: 6890960Abstract: Extracts of vetiver oil were found to significantly repel termites. In one extract, nootkatone was isolated and found to be a significant repellent and toxicant of termites. Nootkatone significantly decreased food consumption, decreased tunneling behavior, and increased mortality in termites. Nootkatone is an effective repellent and toxicant of termites either by itself or as an addition to other materials or substrates, including mulches made from vetiver grass roots or other wood products. Nootkatone can also be used to protect construction wood from attack by Formosan subterranean termites. Nootkatone as a repellent is non-toxic to humans and other mammals and is environmentally safe. In addition, ?-cedrene was found to be a weak termite repellent; and both zizanol and bicyclovetivenol were found to be repellents and toxicants of termites.Type: GrantFiled: October 18, 2000Date of Patent: May 10, 2005Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical CollegeInventors: Gregg Henderson, Roger A. Laine, Donald O. Heumann, Feng Chen, Betty C. R. Zhu
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Publication number: 20050037045Abstract: Several derivatives of naphthalene, including 1?-acetonaphthone, 2?-acetpnaphthone, 1-methoxynaphthalene, and 2-methoxynaphthalene, were discovered to be effective toxicants and repellents of termites, and resulted in significant reduction in termite feeding activity. For example, 2?-acetonaphthone was found to be an effective repellent and feeding deterrent of termites. Termites exposed to concentrations as low as 8 mg/kg sand exhibited a significant reduction in tunneling and feeding activity. Moreover, some of the dead termites had symptoms indicative of a failure to molt. At concentrations ?20 ?g/cm2, 2?-acetonaphthone was a strong repellent. Interestingly, at 160-fold lower concentration (0.125 ?g/cm2), 2?-acetonaphthone stimulated termite feeding activity. As a sand barrier, 2?-acetonaphthone significantly inhibited tunneling and feeding activity in concentrations from 8.33 to 35.0 mg/kg. Molting problems were also identified in termites exposed to 2?-acetonaphthone.Type: ApplicationFiled: August 14, 2003Publication date: February 17, 2005Inventors: Gregg Henderson, Sanaa Ibrahim, Rosemary Patton, Roger Laine, Betty Zhu, Feng Chen
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Publication number: 20040157935Abstract: Extracts of vetiver oil were found to be significant repellents and toxicants of ants, ticks, and cockroaches. Nootkatone was shown to significantly decrease ant invasion and increase mortality in fire ants. Nootkatone is an effective repellent and toxicant of ants either by itself or as an addition to other substrates, including mulches made from vetiver grass roots, diatomaceous earth, alumina, silica, clays; building materials made from either aluminum or wood; and other suitable solid substances. Nootkatone was also a repellent and toxicant to ticks; and a repellent to cockroaches. Nootkatone is non-toxic to humans and other mammals and is environmentally safe. In addition, it is believed that other extracts of vetiver oil, specifically &agr;-cedrene, zizanol and bicyclovetivenol, will be effective against ants, ticks, and cockroaches.Type: ApplicationFiled: February 2, 2004Publication date: August 12, 2004Inventors: Gregg Henderson, Donald O. Heumann, Roger A. Laine, Lara Maistrello, Betty C.R. Zhu, Feng Chen
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Publication number: 20040005343Abstract: Two derivatives of nootkatone, tetrahydronootkatone and 1,10-dihydronootkatone, are surprisingly effective as repellents of termites and mosquitos. Tetrahydronootkatone and 1,10-dihydronootkatone were shown to effectively repel termites at concentrations as low as 2 &mgr;g/ml and 12.5 &mgr;g/ml, respectively. Tetrahydronootkatone was shown to repel mosquitos at a concentration of 5%. Tetrahydronootkatone is an effective repellent of termites either by itself or as an addition to other substrates, including mulches made from wood products or other cellulose-containing material. Tetrahydronootkatone or 1,10-dihydronootkatone can be used to protect construction wood from attack by Formosan subterranean termites, either alone or used in combination with other compounds known to repel termites. It is also believed that these compounds will prove effective in repelling ants, ticks, and cockroaches. These derivatives of nootkatone are non-toxic to humans and other mammals and environmentally safe.Type: ApplicationFiled: July 3, 2002Publication date: January 8, 2004Inventors: Betty C. R. Zhu, Gregg Henderson, Roger A. Laine
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Publication number: 20030073748Abstract: Extracts of vetiver oil were found to be significant repellents and toxicants of ants, ticks, and cockroaches. Nootkatone was shown to significantly decrease ant invasion and increase mortality in fire ants. Nootkatone is an effective repellent and toxicant of ants either by itself or as an addition to other substrates, including mulches made from vetiver grass roots, diatomaceous earth, alumina, silica, clays; building materials made from either aluminum or wood; and other suitable solid substances. Nootkatone was also a repellent and toxicant to ticks; and a repellent to cockroaches. Nootkatone is non-toxic to humans and other mammals and is environmentally safe. In addition, it is believed that other extracts of vetiver oil, specifically &agr;-cedrene, zizanol and bicyclovetivenol, will be effective against ants, ticks, and cockroaches.Type: ApplicationFiled: August 17, 2001Publication date: April 17, 2003Inventors: Gregg Henderson, Donald O. Heumann, Roger A. Laine, Lara Maistrello, Betty C.R. Zhu, Feng Chen
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Patent number: 6352703Abstract: Significant concentrations of naphthalene were detected in carton nests of Formosan subterranean termites, Coptotermes formosanus Shiraki, collected from Florida, Hawaii, and Louisiana. This is the first report of naphthalene being associated with termites or any other insects. Naphthalene and other compounds associated with termite carton nests may be used to increase termite bait acceptance. New attractant molecules include 2-phenoxyethanol. New feeding stimulants include ergosterol. A list of volatile compounds associated with termite nests is presented, compounds that may be used to detect termite nests.Type: GrantFiled: June 7, 2000Date of Patent: March 5, 2002Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical CollegeInventors: Gregg Henderson, Jian Chen, Roger A. Laine
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Patent number: 6184027Abstract: Catalytically inactive murein binding enzyme diagnostic reagents and methods and kits for detecting eubacteria and fungus in biological samples.Type: GrantFiled: March 4, 1999Date of Patent: February 6, 2001Assignees: Anomeric, Inc., Board of Supervisors Louisiana State UniversityInventors: Roger A. Laine, Wai Chun.Jennifer Lo
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Patent number: 6159719Abstract: Murein binding polypeptide and antibiotic diagnostic reagents, methods and kits for detecting eubacteria and fungus in biological samples.Type: GrantFiled: March 3, 1999Date of Patent: December 12, 2000Assignees: Anomeri, Inc., Board of Supervisors Louisiana State UniversityInventors: Roger A. Laine, Wai Chun Jennifer Lo
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Patent number: 6121420Abstract: A 134 kDa, calcium-independent, chitin-binding lectin called chitovibrin is secreted by marine bacteria of the genus Vibnio. The secretion of chitovibrin is inducible by chitin or chitin-oligomers. Chitovibrin shows no apparent enzymatic activity, but has a strong affinity for chitin and for chito-oligomers dp9 and larger. The protein has an isoelectric pH of 3.6, shows thermal tolerance, binds chitin with an optimum at pH 6 and is active in 0-4 M NaCl. Chitovibrin is useful as a stain for fungi and other chitin-containing organisms. Chitovibrin may be used to detect the presence of chitin, particularly in diagnosing fungal infections in humans, animals, and plant materials. Fungal infections are a particular problem in immunocompromised hosts such as AIDS patients and bone marrow transplant patients, because they can cause opportunistic infections. The chitovibrin diagnostic method allows the convenient, broad spectrum diagnosis of fungal infections in tissue samples or in body fluids.Type: GrantFiled: April 13, 1999Date of Patent: September 19, 2000Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical CollegeInventor: Roger A. Laine