Patents by Inventor Roger A. Parker

Roger A. Parker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5039695
    Abstract: This invention relates to the method of using aryl- or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds to treat interleukin-1 mediated conditions.
    Type: Grant
    Filed: February 27, 1990
    Date of Patent: August 13, 1991
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Roger A. Parker, George Ku
  • Patent number: 5021461
    Abstract: The present invention relates to a method of lowering blood glucose in a patient afflicted with diabetes mellitus comprising administering to said patient a therapeutically effective glucose lowering amount of a 4,4'-bis(2,6-di-alkylphenol). The present invention also relates to a process for making 4,4'-bis(2,6-di-alkyl-phenol).
    Type: Grant
    Filed: August 21, 1990
    Date of Patent: June 4, 1991
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Keith M. Robinson, Simon J. T. Mao, Roger A. Parker, Richard L. Jackson
  • Patent number: 5001282
    Abstract: The present invention relates to a method of lowering blood glucose in a patient afflicted with diabetes mellitus comprising administering to said patient a therapeutically effective glucose lowering amount of a 4,4'-bis(2,6-di-alkyl-phenol). The present invention also relates to a process for making 4,4'-bis(2,6-di-alkyl-phenol).
    Type: Grant
    Filed: July 26, 1989
    Date of Patent: March 19, 1991
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Keith M. Robinson, Simon J. T. Mao, Roger A. Parker, Richard L. Jackson
  • Patent number: 4980371
    Abstract: Furan ketone derivatives thereof having antiretrovirus activity and effective in a method of treatment of a retrovirus infection, have the formula ##STR1## wherein Y is a bond, oxygen or divalent sulfur; n is 0 or 1; R is a straight or branched C.sub.8-20 alkyl chain or a straight or branched C.sub.8-20 alkenyl chain having from 1 to 4 double bonds; and R.sub.1 is C.sub.1-6 alkyl.
    Type: Grant
    Filed: November 27, 1989
    Date of Patent: December 25, 1990
    Assignee: Merrell Dow Pharmaceuticals
    Inventors: Roger A. Parker, Sai P. Sunkara
  • Patent number: 4977185
    Abstract: Novel furan ketone derivatives having antiretrovirus activity and effective in a method of treatment of a retrovirus infection, have the formula ##STR1## wherein Y represents a bond, oxygen or divalent sulfur; Ar represents phenyl or naphthylenyl; n is 0 or 1; m is an integer of from 4 to 10; and R.sub.1 represents C.sub.1-6 alkyl.
    Type: Grant
    Filed: November 27, 1989
    Date of Patent: December 11, 1990
    Assignee: Merrell Dow Pharmaceuticals
    Inventors: Roger A. Parker, Sai P. Sunkara
  • Patent number: 4939173
    Abstract: Aryloxyalkanol derivatives having the formulaAr--O(CH.sub.2).sub.n OHwherein n is an integer from 3 to 8 and Ar is (1) 1- or 2-naphthylenyl, (2) phenyl optionally substituted by from 1 to 3 C.sub.1-4 lower alkyl groups, or (3) a diphenyl moiety of structure ##STR1## wherein Y is a bond, CH.sub.2 or CH.sub.2 O, and esters thereof have antiretrovirus activity and are effective in a method for treating a retrovirus infection.
    Type: Grant
    Filed: December 14, 1988
    Date of Patent: July 3, 1990
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Roger A. Parker, Sai P. Sunkara
  • Patent number: 4738984
    Abstract: Compounds of the following general structure are useful as antirhinovirus agents: ##STR1## wherein R is a straight or branched hydrocarbon chain having from 12 to 16 carbon atoms and is saturated or is unsaturated having from 1 to 4 double bonds.
    Type: Grant
    Filed: July 10, 1986
    Date of Patent: April 19, 1988
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventor: Roger A. Parker
  • Patent number: 4602099
    Abstract: Compounds of the following general structure are useful as antirhinovirus agents: ##STR1## wherein R is a straight or branched hydrocarbon chain having from 12 to 16 carbon atoms and is saturated or is unsaturated having from 1 to 4 double bonds.
    Type: Grant
    Filed: September 16, 1982
    Date of Patent: July 22, 1986
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventor: Roger A. Parker
  • Patent number: 4335098
    Abstract: This invention relates to acylated furanyl acrylic acids, salts, esters and amides, to acylated thienyl acrylic acids, salts, esters and amides, and to their use as hypolipidemic agents, and to the processes for producing said compounds.
    Type: Grant
    Filed: May 26, 1981
    Date of Patent: June 15, 1982
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventor: Roger A. Parker
  • Patent number: 4229467
    Abstract: Compounds of the Formula ##STR1## wherein R is H or C.sub.1-4 alkyl; R.sub.1 is H or C.sub.1-4 alkyl; and R.sub.2 is straight or branched chain alkyl of 10-20 carbon atoms, straight or branched chain alkenyl of 10-20 carbon atoms, straight or branched chain alkadienyl of 10-20 carbon atoms or straight or branched chain alkatrienyl of 10-20 carbon atoms and the pharmaceutically acceptable salts thereof, are useful as hypolipidemic agents.
    Type: Grant
    Filed: August 16, 1979
    Date of Patent: October 21, 1980
    Assignee: Richardson-Merrell Inc.
    Inventor: Roger A. Parker
  • Patent number: 4192895
    Abstract: Compounds of the following general structure are useful as antirhinovirus agents: ##STR1## wherein Y is a bond, oxygen or divalent sulfur; R is a straight or branched hydrocarbon chain having from 6 to 20 carbon atoms and is saturated or unsaturated having from 1 to 4 double bonds when R has from 10 to 20 carbon atoms and 1 or 2 double bonds when R has from 6 to 9 carbon atoms; and R.sub.1 is hydrogen or a straight or branched alkyl group of from 1 to 4 carbon atoms.
    Type: Grant
    Filed: July 31, 1978
    Date of Patent: March 11, 1980
    Assignee: Richardson-Merrell Inc.
    Inventor: Roger A. Parker
  • Patent number: 4187319
    Abstract: Substituted benzaldehydes of the following general structure are useful as hypolipidemic agents: ##STR1## wherein Y is selected from oxygen and divalent sulfur; R is selected from a straight or branched saturated hydrocarbon chain having from 10 to 20 carbon atoms and a straight or branched unsaturated hydrocarbon chain having from 10 to 20 carbon atoms and from 1 to 4 double bonds.
    Type: Grant
    Filed: June 2, 1977
    Date of Patent: February 5, 1980
    Assignee: Richardson-Merrell Inc.
    Inventors: Thomas R. Blohm, J. Martin Grisar, Roger A. Parker
  • Patent number: 4146623
    Abstract: Substituted furoic acids and esters and pharmaceutically acceptable salts thereof of the following general structure are useful as hypolipidemic agents: ##STR1## wherein Y represents oxygen or divalent sulfur; R represents a straight or branched alkyl chain containing from 10 to 20 carbon atoms and may be saturated or may be unsaturated containing from 1 to 4 double bonds; R.sup.1 represents hydrogen, straight or branched lower alkyl of from 1 to 6 carbon atoms, benzyl, phenethyl, pyridylmethyl, alkane-poly-yl containing from 3 to 6 carbon atoms, 1,2,3,4,5,6-cyclohexanehexayl, or Z; Z represents ##STR2## wherein n is an integer of 2 or 3; R.sup.2 represents straight or branched lower alkyl of from 1 to 4 carbon atoms, or acyl; R.sup.3 represents hydrogen or straight or branched lower alkyl of from 1 to 4 carbon atoms with the proviso that when R.sup.3 is hydrogen, R.sup.2 is acyl; or when R.sup.2 is other than acyl, R.sup.2 and R.sup.
    Type: Grant
    Filed: April 24, 1978
    Date of Patent: March 27, 1979
    Assignee: Richardson-Merrell Inc.
    Inventor: Roger A. Parker
  • Patent number: 4114038
    Abstract: A sensing head for use in turbidity measurements has a body with a sensing surface, for example a photocell enclosure, which is immersed in liquid in use of the head. Periodic cleaning of the sensing surface is effected by powered movement, for example under control of an electric motor, of the body relative to a housing in which a wiping element such as an O-ring is seated. As applied to a photoelectric head a further body enclosing a light source may be mounted for movement with the photocell enclosure to be wiped clean by a separate wiping element in the housing.
    Type: Grant
    Filed: April 4, 1977
    Date of Patent: September 12, 1978
    Assignee: Partech (Electronics) Limited
    Inventor: Adrian Roger Parker
  • Patent number: 4110351
    Abstract: Substituted furoic acids and esters and pharmaceutically acceptable salts thereof of the following general structure are useful as hypolipidemic agents: ##STR1## wherein Y represents oxygen or divalent sulfur; R represents a straight or branched alkyl chain containing from 10 to 20 carbon atoms and may be saturated or may be unsaturated containing from 1 to 4 double bonds; R.sup.1 represents hydrogen, straight or branched lower alkyl of from 1 to 6 carbon atoms, benzyl, phenethyl, pyridylmethyl, alkane-poly-yl containing from 3 to 6 carbon atoms, 1,2,3,4,5,6-cyclohexanehexayl, or Z; Z represents(A) the group ##STR2## wherein n is an integer of 2 or 3; R.sup.2 represents straight or branched lower alkyl of from 1 to 4 carbon atoms, or acyl; R.sup.3 represents hydrogen or straight or branched lower alkyl of from 1 to 4 carbon atoms with the proviso that when R.sup.3 is hydrogen, R.sup.2 is acyl; or when R.sup.2 is other than acyl, R.sup.2 and R.sup.
    Type: Grant
    Filed: April 2, 1973
    Date of Patent: August 29, 1978
    Assignee: Richardson-Merrell Inc.
    Inventor: Roger A. Parker
  • Patent number: 3990795
    Abstract: A turbidity measuring instrument has a chamber through which liquid to be examined flows, the chamber having a constant head inlet and a weir overflow outlet so that a static liquid level is maintained in the chamber, light being directed vertically into the liquid from above and back-scattered light from particles suspended in the liquid being measured photoelectrically by a detector head located in a sealed housing with a light source above the liquid level.
    Type: Grant
    Filed: October 4, 1974
    Date of Patent: November 9, 1976
    Assignee: Partech (Electronics) Limited
    Inventor: Adrian Roger Parker