Abstract: A system includes a catheter (10) having a low pressure balloon (42) at of one end thereof, a precise, low pressure, low volume fluid infusion means (41) and a pressure sensor (43). The balloon (42) is introduced to a body lumen, such as a blood vessel, and inflated to a pressure at or just above physiologic, typically being below 200 mmhg. From the balloon volume at a particular pressure, the internal cross-sectional area and diameter of the vessel can be calculated. Additional calculations can be made at other pressures below 200 mmhg to determine compliance of the vessel.

Abstract: An optical pH sensor and a gas sensor utilizing the pH sensor. The pH sensor includes an indicator whose absorbance is a function of the concentration of hydronium ions in a media surrounding the indicator. Light transmitted and reflected through the indicator of the sensor undergoes an absorption that is characteristic of the concentration of the hydrogen ion. The pH sensor can be used as to sense the concenration of a gas in a sample by surrounding the indicator with a liquid or liquid-containing media that changes pH as it is exposed to the gas, and separating the indicator and liquid or liquid-containing media from the gas with a membrane that is permeable to the gas to be measured. A measuring system used with the sensors transmits coherent radiation to the sensor through an optical fiber, separates the radiation returning from the sample into two wavelength bands, and digitally samples the photocurrents produced within the two wavelength bands.