Patents by Inventor Roger Andrew Jeffs

Roger Andrew Jeffs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Buffer solutions having selective bactericidal activity against gram negative bacteria and methods of using same
    Patent number: 9327031
    Abstract: Buffer solutions for pharmaceutical preparations that have bactericidal activity preferentially against gram negative bacteria are provided. The buffers have a pH of greater than about 10 or less than about 4.5 with low buffer capacity. Methods of their use in reducing the occurrence of blood stream infections in a mammal is also provided.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: May 3, 2016
    Assignee: United Therapeutics Corporation
    Inventors: Roger Andrew Jeffs, David Zaccardelli
  • STABLE SOLUTIONS OF TREPROSTINIL
    Publication number: 20140288179
    Abstract: An improved method for administering treprostinil or a salt is described that allows for use of the diluted solution prior to administration for a longer period of time to avoid wasted medication.
    Type: Application
    Filed: June 12, 2014
    Publication date: September 25, 2014
    Inventors: David Zaccardelli, Roger Andrew Jeffs
  • BUFFER SOLUTIONS HAVING SELECTIVE BACTERICIDAL ACTIVITY AGAINST GRAM NEGATIVE BACTERIA AND METHODS OF USING SAME
    Publication number: 20140194520
    Abstract: Buffer solutions for pharmaceutical preparations that have bactericidal activity preferentially against gram negative bacteria are provided. The buffers have a pH of greater than about 10 or less than about 4.5 with low buffer capacity. Methods of their use in reducing the occurrence of blood stream infections in a mammal is also provided.
    Type: Application
    Filed: January 17, 2014
    Publication date: July 10, 2014
    Applicant: United Therapeutics Corporation
    Inventors: Roger Andrew Jeffs, David Zaccardelli
  • Buffer solutions having selective bactericidal activity against gram negative bacteria and methods of using same
    Patent number: 8658694
    Abstract: Buffer solutions for pharmaceutical preparations that have bactericidal activity preferentially against gram negative bacteria are provided. The buffers have a pH of greater than about 10 or less than about 4.5 with low buffer capacity. Methods of their use in reducing the occurrence of blood stream infections in a mammal is also provided.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: February 25, 2014
    Assignee: United Therapeutics Corporation
    Inventors: Roger Andrew Jeffs, David Zaccardelli
  • Buffer solutions having selective bactericidal activity against gram negative bacteria and methods of using same
    Patent number: 8653137
    Abstract: Buffer solutions for pharmaceutical preparations that have bactericidal activity preferentially against gram negative bacteria are provided. The buffers have a pH of greater than about 10 or less than about 4.5 with low buffer capacity. Methods of their use in reducing the occurrence of blood stream infections in a mammal is also provided.
    Type: Grant
    Filed: June 7, 2013
    Date of Patent: February 18, 2014
    Assignee: United Therapeutics Corporation
    Inventors: Roger Andrew Jeffs, David Zaccardelli
  • Use of treprostinil to treat neuropathic diabetic foot ulcers
    Patent number: 8563614
    Abstract: The present invention describes novel methods for using 9-deoxy-2?,9-?-methano-3-oxa-4,5,6-trinor-3,7-(1?,3?-interphenylene)-13,14-dihydro-prostaglandin F1 (also known as Treprostinil) or its derivative, or a pharmaceutically acceptable salt thereof, for the treatment and/or prevention of foot ulcers in subjects with diabetic neuropathy. The invention also relates to kits for treatment and/or prevention of foot ulcers, comprising an effective amount of Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: October 22, 2013
    Assignee: United Therapeutics Corporation
    Inventors: Michael Wade, Roger Andrew Jeffs, Deborah Strootman
  • BUFFER SOLUTIONS HAVING SELECTIVE BACTERICIDAL ACTIVITY AGAINST GRAM NEGATIVE BACTERIA AND METHODS OF USING SAME
    Publication number: 20130274340
    Abstract: Buffer solutions for pharmaceutical preparations that have bactericidal activity preferentially against gram negative bacteria are provided. The buffers have a pH of greater than about 10 or less than about 4.5 with low buffer capacity. Methods of their use in reducing the occurrence of blood stream infections in a mammal is also provided.
    Type: Application
    Filed: June 7, 2013
    Publication date: October 17, 2013
    Inventors: Roger Andrew Jeffs, David Zaccardelli
  • Use of Treprostinil to treat neuropathic diabetic foot ulcers
    Publication number: 20110092599
    Abstract: The present invention describes novel methods for using 9-deoxy-2?,9-?-methano-3-oxa-4,5,6-trinor-3,7-(1?,3?-interphenylene)-13,14-dihydro-prostaglandin F1 (also known as Treprostinil) or its derivative, or a pharmaceutically acceptable salt thereof, for the treatment and/or prevention of foot ulcers in subjects with diabetic neuropathy. The invention also relates to kits for treatment and/or prevention of foot ulcers, comprising an effective amount of Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: December 20, 2010
    Publication date: April 21, 2011
    Inventors: Michael Wade, Roger Andrew Jeffs, Deborah Strootman
  • Use of Treprostinil to treat neuropathic diabetic foot ulcers
    Patent number: 7879909
    Abstract: The present invention describes novel methods for using 9-deoxy-2?,9-?-methano-3-oxa-4,5,6-trinor-3,7-(1?,3?-interphenylene)-13,14-dihydro-prostaglandin F1 (also known as Treprostinil) or its derivative, or a pharmaceutically acceptable salt thereof, for the treatment and/or prevention of foot ulcers in subjects with diabetic neuropathy. The invention also relates to kits for treatment and/or prevention of foot ulcers, comprising an effective amount of Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 12, 2005
    Date of Patent: February 1, 2011
    Assignee: United Therapeutics Corporation
    Inventors: Michael Wade, Roger Andrew Jeffs, Deborah Strootman
  • Use of treprostinil to improve kidney functions
    Patent number: 7199157
    Abstract: The present invention describes novel methods for using Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof, for improving kidney functions, such as urine output, and treating symptoms associated with kidney malfunction or failure. The invention also relates to kits for the improvement of kidney functions and the treatment of symptoms associated with kidney malfunction or failure, comprising an effective amount of Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: December 16, 2004
    Date of Patent: April 3, 2007
    Assignee: United Therapeutics Corporation
    Inventors: Michael Wade, Roger Andrew Jeffs, Kathryn Bronstein, Deborah Strootman
  • Use of treprostinil to improve kidney functions
    Publication number: 20050165110
    Abstract: The present invention describes novel methods for using Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof, for improving kidney functions, such as urine output, and treating symptoms associated with kidney malfunction or failure. The invention also relates to kits for the improvement of kidney functions and the treatment of symptoms associated with kidney malfunction or failure, comprising an effective amount of Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: December 16, 2004
    Publication date: July 28, 2005
    Inventors: Michael Wade, Roger Andrew Jeffs, Kathryn Bronstein, Deborah Strootman