Patents by Inventor Roger Ariel Alberto

Roger Ariel Alberto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11690923
    Abstract: Multinuclear complexes and methods for preparing them are provided. The discrete multinuclear complexes include a one or more transition metals and a radioisotope having the same coordination geometry as the transition metal. A bridging ligand is coordinated to the transition metal and the radioisotope to link the transition metal and the radioisotope and pendent ligands are coordinated to each of the transition metal and the radioisotope to stabilise the complex. The multinuclear complexes may include a radioisotope or radioelement that can be detected by medical equipment and may find use in therapy and/or the diagnosis of disease in patients.
    Type: Grant
    Filed: July 19, 2021
    Date of Patent: July 4, 2023
    Assignees: UNIVERSITY OF THE FREE STATE, UNIVERSITAT ZURICH
    Inventors: Andreas Roodt, Roger Ariel Alberto, Angelo Frei, Petrus Pennie Mokolokolo, Robin Kim Bollinger, Alice Brink, Dumisani Vincent Kama
  • Publication number: 20210393813
    Abstract: Multinuclear complexes and methods for preparing them are provided. The discrete multinuclear complexes include a one or more transition metals and a radioisotope having the same coordination geometry as the transition metal. A bridging ligand is coordinated to the transition metal and the radioisotope to link the transition metal and the radioisotope and pendent ligands are coordinated to each of the transition metal and the radioisotope to stabilise the complex. The multinuclear complexes may include a radioisotope or radioelement that can be detected by medical equipment and may find use in therapy and/or the diagnosis of disease in patients.
    Type: Application
    Filed: July 19, 2021
    Publication date: December 23, 2021
    Applicants: UNIVERSITY OF THE FREE STATE, UNIVERSITÄT ZÜRICH
    Inventors: Andreas ROODT, Roger Ariel ALBERTO, Angelo FREI, Petrus Pennie MOKOLOKOLO, Robin Kim BOLLINGER, Alice BRINK, Dumisani Vincent KAMA
  • Publication number: 20200330623
    Abstract: Multinuclear complexes and methods for preparing them are provided. The discrete multinuclear complexes include a one or more transition metals and a radioisotope having the same coordination geometry as the transition metal. A bridging ligand is coordinated to the transition metal and the radioisotope to link the transition metal and the radioisotope and pendent ligands are coordinated to each of the transition metal and the radioisotope to stabilise the complex. The multinuclear complexes may include a radioisotope or radioelement that can be detected by medical equipment and may find use in therapy and/or the diagnosis of disease in patients.
    Type: Application
    Filed: December 21, 2018
    Publication date: October 22, 2020
    Applicants: UNIVERSITY OF THE FREE STATE, UNIVERSITÄT ZÜRICH
    Inventors: Andreas ROODT, Roger Ariel ALBERTO, Angelo FREI, Petrus Pennie MOKOLOKOLO, Robin Kim BOLLINGER, Alice BRINK, Dumisani Vincent KAMA
  • Patent number: 8753641
    Abstract: The invention relates to molecules for treatment and diagnosis of tumors and malignancies, comprising a tumor seeking biomolecule, which is coupled to an intercalating moiety, which is capable of complexing a metal, which metal is preferably a radioactive metal, to the use of these molecules and to therapeutic and diagnostic compositions containing them.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: June 17, 2014
    Assignee: University of Zurich
    Inventors: Roger Ariel Alberto, Pascal Jean-Marie Hafliger
  • Publication number: 20090280057
    Abstract: The invention relates to molecules for treatment and diagnosis of tumors and malignancies, comprising a tumor seeking biomolecule, which is coupled to an intercalating moiety, which is capable of complexing a metal, which metal is preferably a radioactive metal, to the use of these molecules and to therapeutic and diagnostic compositions containing them.
    Type: Application
    Filed: July 20, 2009
    Publication date: November 12, 2009
    Applicant: Mallinckrodt Inc.
    Inventors: Roger Ariel Alberto, Pascal Jean-Marie Hafliger
  • Patent number: 7582295
    Abstract: The invention relates to molecules for treatment and diagnosis of tumors and malignancies, comprising a tumor seeking biomolecule, which is coupled to an intercalating moiety, which is capable of complexing a metal, which metal is preferably a radioactive metal, to the use of these molecules and to therapeutic and diagnostic compositions containing them.
    Type: Grant
    Filed: January 30, 2004
    Date of Patent: September 1, 2009
    Assignee: University of Zurich
    Inventors: Roger Ariel Alberto, Pascal Jean-Marie Hafliger
  • Patent number: 6844425
    Abstract: The invention relates to molecules for treatment and diagnosis of tumors and malignancies, comprising a tumor seeking biomolecule, which is coupled to an intercalating moiety, which is capable of complexing a metal, which metal is preferably a radioactive metal, to the use of these molecules and to therapeutic and diagnostic compositions containing them.
    Type: Grant
    Filed: February 24, 2000
    Date of Patent: January 18, 2005
    Assignee: Mallinckrodt Inc.
    Inventors: Roger Ariel Alberto, Pascal Jean-Marie Hafliger