Abstract: The present invention relates to compositions for the delivery of molecules such as a peptide, a nucleic acid and/or a small molecule drug. In particular, the present invention relates to an extracellular vesicle (EV) loaded with a peptide, a nucleic acid and/or a small molecule drug, along with methods of producing said EV.

Abstract: A method of controlling a vehicle climate system having a plurality of zones, wherein the plurality of zones includes a primary zone for a driver of the vehicle and one or more secondary zones for one or more passengers of the vehicle, the method including determining whether one or more of the plurality of zones is occupied by a person, receiving data indicative of a target temperature of each of the occupied zones, receiving data indicative of a target temperature in the primary zone, determining when one or more of the occupied zones becomes unoccupied, and adjusting the target temperature of one or more of the unoccupied zones to an adjusted target temperature. The adjusted target temperature is a function of the target temperature in the primary zone.

Abstract: Automated inspection technology is integrated with a cylindrical container print decorator machine to optimize the decoration process by making critical process and machine information properly and immediately available for corrective adjustments to the process. With this information, a high speed decoration machine operator will be made directly aware of the portions or subsystems of the decorator machine not functioning properly. The information directly facilitates, and can even recommend, corrective adjustments that are necessary to the decorator to better optimize printing functions. It is possible to use this information to optimize the operation of the decorator. It is possible to use this information by way of a properly configured control system, after specific augmentation capabilities are added to the decorator machine, to automatically close the loops with specific decorator printing machine parts or subsystems to dramatically improve the decorating process even while the machine is printing.

Abstract: A method of controlling a vehicle climate system having a plurality of zones, wherein the plurality of zones includes a primary zone for a driver of the vehicle and one or more secondary zones for one or more passengers of the vehicle, the method including determining whether one or more of the plurality of zones is occupied by a person, receiving data indicative of a target temperature of each of the occupied zones, receiving data indicative of a target temperature in the primary zone, determining when one or more of the occupied zones becomes unoccupied, and adjusting the target temperature of one or more of the unoccupied zones to an adjusted target temperature. The adjusted target temperature is a function of the target temperature in the primary zone.

Abstract: A method for controlling a temperature regulated system within the cabin of a vehicle. The method comprises providing a first temperature sensor and a second temperature sensor, the temperature sensors being located within the cabin such that the first temperature sensor is located at a substantially higher level than the second temperature sensor when the vehicle is on a level surface. The method further comprises calculating TR, an estimated temperature, wherein TR is calculated using T1, the temperature measured by the first temperature sensor and T2, the temperature measured by the second temperature sensor. The method then comprises operating the temperature regulation system according to the calculated value TR for a predefined period of time after start up, and thereafter operating the temperature regulation system according to the measured value of T2.

Abstract: Embodiments of the invention provide air conditioning system for use in a motor vehicle, the air conditioning system comprising a controller, at least one primary vent and an air delivery apparatus for location in a dashboard of a motor vehicle, the apparatus comprising: at least one secondary vent; and means for moving the at least one secondary vent between a retracted position in which the at least one secondary vent lies rearward of an A surface of the dashboard and a deployed position in which the at least one secondary vent is exposed for delivery of air to a zone of the vehicle, the controller being operable to: control the air conditioning system to provide a flow of air from the at least one primary vent while the air delivery apparatus is in a retracted position; and control the at least one vent to assume the deployed position responsive to a demand for a flow of air from the at least one secondary vent.

Abstract: Embodiments of the invention provide air conditioning system for use in a motor vehicle, the air conditioning system comprising a controller, at least one primary vent and an air delivery apparatus for location in a dashboard of a motor vehicle, the apparatus comprising: at least one secondary vent; and means for moving the at least one secondary vent between a retracted position in which the at least one secondary vent lies rearward of an A surface of the dashboard and a deployed position in which the at least one secondary vent is exposed for delivery of air to a zone of the vehicle, the controller being operable to: control the air conditioning system to provide a flow of air from the at least one primary vent while the air delivery apparatus is in a retracted position; and control the at least one vent to assume the deployed position responsive to a demand for a flow of air from the at least one secondary vent.

Abstract: The invention relates to a modular pod mattress used for sleeping. The mattress includes a structural frame having bottom rails, guide rails and a dividing rail. A plurality of modular pods are secured to the frame to form the customized mattress that relates directly to the height and eight distribution of an individual's body parts to provide the maximum quality sleep environment unique to that individual. The modular pods include a plurality of spring members, which may have varying elasticity or resistant levels. The modular pods are supported by a support platform that prevents the pods from sagging or deflecting during use of the mattress. A horizontal scale system may be utilized to determine the specific weight of a particular body part, e.g., head, shoulders, thorax, buttocks, thighs, calves and feet, of the user.

Abstract: A modular pod mattress with an integral mattress subsurface platform rail system, a plurality of modular pods to be securely fitted into the mattress subsurface platform rail system, a first compartment to house a mattress lining, and a second compartment to house a mattress topper. The mattress subsurface platform rail system comprises a plurality of rails for forming a series of track mounting spaces for receiving and securing the plurality of modular pods. Each modular pod consists of a plurality of coils springs with varying elasticity that is dependent on the user's height and weight distribution. The modular pods may be removed and replaced pod by pod once worn as opposed to replacing the entire mattress.

Abstract: A method for controlling a temperature regulated system within the cabin of a vehicle. The method comprises providing a first temperature sensor and a second temperature sensor, the temperature senseors being located within the cabin such that the first temperature sensor is located at a substantially higher eve than the second temperature sensor when the vehicle is on a level surface. The method further comprises calculating TR, an estimated temperature, wherein TR is calculated using T1, the temperature measured by the first temperature sensor and T2, the temperature measured by the second temperature sensor. The method then comprises operating the temperature regulation system according to the calculated value TR for a predefined period of time after start up, and thereafter operating the temperature regulation system according to the measured value of T2.

Abstract: An air conditioning system for supplying air conditioned air to a passenger compartment of a motor vehicle has left and right hand side distribution ducts connected to a blower by a common distribution chamber. The blower causes air to flow through the common distribution chamber into the left and right hand side distribution ducts via an air conditioning unit. Each of the distribution ducts includes a distribution valve to vary the flow through the respective distribution duct and through a dump duct that exhausts air outside of the passenger compartment. Each of the dump ducts has the same resistance to flow as the respective distribution duct to which it is connected. The flow from the distribution ducts is adjusted by varying the proportion of air that flows through the cooperating dump duct without affecting the flow from the other distribution duct or requiring the blower speed to be altered.

Abstract: Embodiments of the invention provide air conditioning system for use in a motor vehicle, the air conditioning system comprising a controller, at least one primary vent and an air delivery apparatus for location in a dashboard of a motor vehicle, the apparatus comprising: at least one secondary vent; and means for moving the at least one secondary vent between a retracted position in which the at least one secondary vent lies rearward of an A surface of the dashboard and a deployed position in which the at least one secondary vent is exposed for delivery of air to a zone of the vehicle, the controller being operable to: control the air conditioning system to provide a flow of air from the at least one primary vent while the air delivery apparatus is in a retracted position; and control the at least one vent to assume the deployed position responsive to a demand for a flow of air from the at least one secondary vent.

Abstract: Systems and methods for improving the reliability of a hub-spoke communications system use a first antenna and a second antenna at the hub terminal. Spread spectrum transmission from the hub terminal uses the first antenna, and the second antenna is enabled when blockage between the first antenna and any one of the spoke terminals is present. The first antenna and the second antenna have substantially orthogonal polarizations. The spread spectrum transmissions from the first antenna and second antenna have different pseudonoise code timing so that the received transmissions are offset by at least one chip interval from each other.

Abstract: Automated inspection technology is integrated with a cylindrical container print decorator machine to optimize the decoration process by making critical process and machine information properly and immediately available for corrective adjustments to the process. With this information, a high speed decoration machine operator will be made directly aware of the portions or subsystems of the decorator machine not functioning properly. The information directly facilitates, and can even recommend, corrective adjustments that are necessary to the decorator to better optimize printing functions. It is possible to use this information to optimize the operation of the decorator. It is possible to use this information by way of a properly configured control system, after specific augmentation capabilities are added to the decorator machine, to automatically close the loops with specific decorator printing machine parts or subsystems to dramatically improve the decorating process even while the machine is printing.

Abstract: An air conditioning system 120 for supplying air conditioned air to a passenger compartment 116 of a motor vehicle 110 is disclosed having left and right hand side distribution ducts 111L, 111R connected to a blower 122 by a common distribution chamber 121. The blower 122 is used to cause air to flow through the common distribution chamber 121 into the left and right hand side distribution ducts 111L, 111R via an air conditioning unit 123. Each of the distribution ducts 111L, 111R includes a distribution valve 130L, 130R used to vary the flow through the respective distribution duct 111L, 111R and through a dump duct 112L, 112R that exhausts air outside of a passenger compartment 116 of the motor vehicle 110. Each of the dump ducts 112L, 112R has the same resistance to flow as the respective distribution duct 111L, 111R to which it is connected.

Abstract: A method of testing a mass flow rate meter functioning on the Coriolis principle, in which an apparatus of the mass flow rate meter is subjected to a predetermined oscillation excitation and the associated oscillation response is recorded. Then the recorded oscillation response is compared with a previously recorded oscillation response. Testing of the Coriolis mass flow rate meter with regard, for example, to error tolerances in the manufacturing or with regard to a calibration condition is thereby enabled.

Abstract: An electromagnetic flowmeter calibration verification device for a flow tube comprises a first electrode, attachable to the flow tube, for transmitting, in use, a test current into the flow tube, and a second electrode, attachable to the flow tube, for receiving, in use, the test current transmitted through the flow tube. The device is arranged such that, in use, the test current, when passing from one electrode to another, passes through liquid in the flow tube. The device further comprises a third electrode, attachable to the flow tube, such that, in use, a voltage generated due to current distribution within the flow tube when the test current is passing within the tube is determined, and means for generating an output signal to a user if the voltage generated is outside a predetermined range. A method of verifying the calibration of an electromagnetic flowmeter for a flow tube is also provided.

Abstract: A method of testing a mass flow rate meter functioning on the Coriolis principle, in which an apparatus of the mass flow rate meter is subjected to a predetermined oscillation excitation and the associated oscillation response is recorded. Then the recorded oscillation response is compared with a previously recorded oscillation response. Testing of the Coriolis mass flow rate meter with regard, for example, to error tolerances in the manufacturing or with regard to a calibration condition is thereby enabled.