Abstract: Systems and methods for generating a three-dimensional image of an object from multiple two-dimensional images acquired using a magnetic resonance imaging (“MRI”) system are provided. The three-dimensional image has high spatial resolution in all three spatial dimensions. The multiple two-dimensional images can be acquired in one or more orientations (e.g., axial, coronal, sagittal, oblique). The in-plane resolution of these images can be several times finer than the through-plane resolution (i.e., the slice thickness). The images are Fourier transformed along their respective slice orientation direction and processed using the slice profile to generate a Fourier representation of the three-dimensional image with the target spatial resolution. Inverse Fourier transforming this Fourier representation generates the desired three-dimensional image.

Abstract: Systems and methods for generating a three-dimensional image of an object from multiple two-dimensional images acquired using a magnetic resonance imaging (“MRI”) system are provided. The three-dimensional image has high spatial resolution in all three spatial dimensions. The multiple two-dimensional images can be acquired in one or more orientations (e.g., axial, coronal, sagittal, oblique). The in-plane resolution of these images can be several times finer than the through-plane resolution (i.e., the slice thickness). The images are Fourier transformed along their respective slice orientation direction and processed using the slice profile to generate a Fourier representation of the three- dimensional image with the target spatial resolution. Inverse Fourier transforming this Fourier representation generates the desired three-dimensional image.

Abstract: A series of MR examinations of a patient are performed and the acquired images are aligned with each other so that small anatomic changes can be detected when images are compared. Alignment is achieved by acquiring navigator signals during each examination which are analyzed to measure patient misalignment from one examination to the next. The rotational and translational misalignment information is used to either prospectively or retrospectively align the MR images.