Patents by Inventor Roger C. Wiegand

Roger C. Wiegand has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Small molecule inhibitors of dihydroorotate dehydrogenase
    Patent number: 8703811
    Abstract: Inhibitors of dihydroorotate dehydrogenase (DHODH) for the Plasmodium enzyme have been identified and characterized. The inhibitors have high specificity, submicromolar efficacy against cultured parasite strains, exhibit drug-like properties, and are not overtly cytotoxic.
    Type: Grant
    Filed: May 7, 2009
    Date of Patent: April 22, 2014
    Assignees: Genzyme Corporation, Massachusetts Institute of Technology, President and Fellows of Harvard College
    Inventors: Cecilia Bastos, Michael L. Booker, Cassandra A. Celatka, Jon C. Clardy, Joseph Cortese, Vishal P. Patel, Renato Skerlj, Roger C. Wiegand, Dyann F. Wirth
  • Plant polymorphic markers and uses thereof
    Publication number: 20110281765
    Abstract: The present invention is in the field of plant genetics. More specifically, the invention relates to nucleic acid markers associated with Arabidopsis thaliana ecotypes. The invention also relates to methods for detecting polymorphisms. The invention further relates to methods of using nucleic acid markers, for example, for genome mapping, gene identification, gene isolation and gene analysis.
    Type: Application
    Filed: December 29, 2003
    Publication date: November 17, 2011
    Inventors: David F. Bush, Steven D. Rounsley, Roger C. Wiegand
  • SMALL MOLECULE INHIBITORS OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE
    Publication number: 20110130381
    Abstract: Inhibitors of dihydroorotate dehydrogenase (DHODH) for the Plasmodium enzyme have been identified and characterized. The inhibitors have high specificity, submicromolar efficacy against cultured parasite strains, exhibit drug-like properties, and are not overtly cytotoxic.
    Type: Application
    Filed: May 7, 2009
    Publication date: June 2, 2011
    Inventors: Cecilia Bastos, Michael L. Booker, Cassandra A. Celatka, Jon C. Clardy, Joseph Cortese, Vishal P. Patel, Renato Skerlj, Roger C. Wiegand, Dyann F. Wirth
  • Plant polymorphic markers and uses thereof
    Publication number: 20090215647
    Abstract: The present invention is in the field of plant genetics. More specifically, the invention relates to nucleic acid markers associated with Arabidopsis thaliana ecotypes. The invention also relates to methods for detecting polymorphisms. The invention further relates to methods of using nucleic acid markers, for example, for genome mapping, gene identification, gene isolation and gene analysis.
    Type: Application
    Filed: June 24, 2008
    Publication date: August 27, 2009
    Inventors: David F. Bush, Steven D. Rounsley, Roger C. Wiegand
  • Plant polymorphic markers and uses thereof
    Publication number: 20090075829
    Abstract: The present invention is in the field of plant genetics. More specifically, the invention relates to nucleic acid markers associated with Arabidopsis thaliana ecotypes. The invention also relates to methods for detecting polymorphisms. The invention further relates to methods of using nucleic acid markers, for example, for genome mapping, gene identification, gene isolation and gene analysis.
    Type: Application
    Filed: June 24, 2008
    Publication date: March 19, 2009
    Inventors: David F. Bush, Steven D. Rounsley, Roger C. Wiegand
  • Myxococcus xanthus genome sequences and uses thereof
    Patent number: 6833447
    Abstract: The present invention relates to nucleic acid sequences from the bacterium, Myxococcus xanthus and, in particular, to genomic DNA sequences. The invention encompasses nucleic acid molecules present in non-coding regions as well as nucleic acid molecules that encode proteins and fragments of proteins. In addition, proteins and fragments of proteins so encoded and antibodies capable of binding the proteins are encompassed by the present invention. The invention also encompasses oligonucleotides including primers, e.g. useful for amplifying nucleic acid molecules, and collections of nucleic acid molecules and oligonucleotides, e.g. in microarrays. The invention also provides constructs and transgenic cells and organisms comprising nucleic acid molecules of the invention.
    Type: Grant
    Filed: July 10, 2001
    Date of Patent: December 21, 2004
    Assignee: Monsanto Technology, LLC
    Inventors: Barry S. Goldman, Gregory J. Hinkle, Steven C. Slater, Roger C. Wiegand
  • Human guanylin
    Patent number: 5969097
    Abstract: A novel pentadecapeptide is disclosed which is useful for the control of intestinal fluid absorption and that has the following amino acid sequencePro-Gly-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala- 1 5 10 - Ala-Cys-Thr-Gly-Cys (SEQ ID NO.
    Type: Grant
    Filed: June 23, 1992
    Date of Patent: October 19, 1999
    Assignee: G. D. Searle & Co.
    Inventors: Roger C. Wiegand, Mark G. Currie, Kam Fook Fok