Patents by Inventor Roger DiPaolo

Roger DiPaolo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8391582
    Abstract: An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: March 5, 2013
    Assignee: Affymetrix, Inc.
    Inventors: Nathan K. Weiner, Patrick J. Odoy, Eric Schultz, Mark Jones, James T. Overbeck, Herman DeWeerd, David A. Stura, Albert K. Bukys, Tim J. Woolaver, Thomas P. Regan, David Bradbury, Eric E. McKenzie, Roger DiPaolo, Christopher Miles, Joel M. Katz, Oleinik-Ovod Ksenia
  • Publication number: 20120235016
    Abstract: An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values.
    Type: Application
    Filed: May 25, 2012
    Publication date: September 20, 2012
    Applicant: Affymetrix, Inc.
    Inventors: Nathan K. Weiner, Patrick J. Odoy, Eric Schultz, Mark Jones, James Overbeck, Herman Deweerd, David A. Stura, Albert Bukys, Tim Woolaver, Thomas P. Regan, David Bradbury, Eric Earl McKenzie, Roger DiPaolo, Christopher Miles, Joel Katz, Ksenia Oleinik-Ovod
  • Patent number: 8208710
    Abstract: An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values.
    Type: Grant
    Filed: June 9, 2011
    Date of Patent: June 26, 2012
    Assignee: Affymetrix, Inc.
    Inventors: Nathan K. Weiner, Patrick J. Odoy, Eric Schultz, Mark Jones, James T. Overbeck, Herman DeWeerd, David A. Stura, Albert K. Bukys, Tim J. Woolaver, Thomas P. Regan, David Bradbury, Eric E. McKenzie, Roger DiPaolo, Christopher Miles, Joel M. Katz, Ksenia Oleinik-Ovod
  • Publication number: 20110243411
    Abstract: An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values.
    Type: Application
    Filed: June 9, 2011
    Publication date: October 6, 2011
    Applicant: AFFYMETRIX, INC.
    Inventors: Nathan K. Weiner, Patrick J. Odoy, Eric Schultz, Mark Jones, James Overbeck, Herman DeWeerd, David A. Stura, Albert Bukys, Tim Woolaver, Thomas P. Regan, David Bradbury, Eric Earl McKenzie, Roger DiPaolo, Christopher Miles, Joel M. Katz, Ksenia Oleink-Ovod
  • Patent number: 7983467
    Abstract: An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values.
    Type: Grant
    Filed: February 11, 2010
    Date of Patent: July 19, 2011
    Assignee: Affymetrix, Inc.
    Inventors: Nathan K. Weiner, Patrick J. Odoy, Eric Schultz, Mark Jones, James Overbeck, Herman Deweerd, David A. Stura, Albert Bukys, Tim Woolaver, Thomas P. Regan, David Bradbury, Eric Earl McKenzie, Roger DiPaolo, Christopher Miles, Joel M. Katz, Ksenia Oleink-Ovod
  • Patent number: 7871812
    Abstract: An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values.
    Type: Grant
    Filed: October 27, 2004
    Date of Patent: January 18, 2011
    Assignee: Affymetrix, Inc.
    Inventors: Nathan K. Weiner, Patrick J. Odoy, Eric Schultz, Mark Jones, James Overbeck, Herman Deweerd, David A. Stura, Albert Bukys, Tim Woolaver, Thomas P. Regan, David Bradbury, Eric Earl McKenzie, Roger DiPaolo, Christopher Miles, Joel M. Katz, Ksenia Oleink-Ovod
  • Publication number: 20100142850
    Abstract: An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values.
    Type: Application
    Filed: February 11, 2010
    Publication date: June 10, 2010
    Applicant: Affymetrix, INC.
    Inventors: Nathan K. Weiner, Patrick J. Odoy, Eric Schultz, Mark Jones, James Overbeck, Herman Deweerd, David A. Stura, Albert Bukys, Tim Woolaver, Thomas P. Regan, David Bradbury, Eric Earl McKenzie, Roger DiPaolo, Christopher Miles, Joel Katz, Ksenia Oleink-Ovod
  • Patent number: 7689022
    Abstract: An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values.
    Type: Grant
    Filed: March 14, 2003
    Date of Patent: March 30, 2010
    Assignee: Affymetrix, Inc.
    Inventors: Nathan K. Weiner, Patrick J. Odoy, Erik Schultz, Mark Jones, James Overbeck, Herman Deweerd, David A. Stura, Albert Bukys, Tim Woolaver, Thomas P. Regan, David Bradbury, Eric Earl McKenzie, Roger DiPaolo, Christopher Miles, Joel Katz, Ksenia Oleink-Ovod
  • Publication number: 20050057676
    Abstract: An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values.
    Type: Application
    Filed: October 27, 2004
    Publication date: March 17, 2005
    Applicant: Affymetrix, INC.
    Inventors: Nathan Weiner, Patrick Odoy, Eric Schultz, Mark Jones, James Overbeck, Herman Deweerd, David Stura, Albert Bukys, Tim Woolaver, Thomas Regan, David Bradbury, Eric McKenzie, Roger DiPaolo, Christopher Miles, Joel Katz, Ksenia Oleink-Ovod
  • Publication number: 20040012676
    Abstract: An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values.
    Type: Application
    Filed: March 14, 2003
    Publication date: January 22, 2004
    Applicant: Affymetrix, Inc., a Corporation Organized under the Laws of Delaware
    Inventors: Nathan K. Weiner, Patrick J. Odoy, Eric Schultz, Mark Jones, James Overbeck, Herman Deweerd, David A. Stura, Albert Bukys, Tim Woolaver, Thomas P. Regan, David Bradbury, Eric Earl McKenzie, Roger DiPaolo, Christopher Miles, Joel Katz, Ksenia Oleink-Ovod