Patents by Inventor Roger G. Kern

Roger G. Kern has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detector using mass spectroscopy for characterization of biological community
    Patent number: 8116981
    Abstract: Provided are methods and systems for rapidly and effectively characterizing a cell as belonging to a particular genus, species, strain, or having a particular phenotype. The methods and systems utilize mass spectrometry and low-energy negative ionization to detect cell surface markers indicative of a particular cell.
    Type: Grant
    Filed: May 28, 2003
    Date of Patent: February 14, 2012
    Assignee: California Institute of Technology
    Inventors: Ara Chutjian, Murray R. Darrach, Roger G. Kern
  • Novel detector using mass spectroscopy for characterization of biological community
    Publication number: 20040049107
    Abstract: Provided are methods and systems for rapidly and effectively characterizing a cell as belonging to a particular genus, species, strain, or having a particular phenotype. The methods and systems utilize mass spectrometry and low-energy negative ionization to detect cell surface markers indicative of a particular cell.
    Type: Application
    Filed: May 28, 2003
    Publication date: March 11, 2004
    Inventors: Ara Chutjian, Murray R. Darrach, Roger G. Kern
  • Real-time biochemical assay telemetering system
    Patent number: 5891649
    Abstract: The present invention is an apparatus and a method of detecting a chemical released by perspiration, typically through sweat and broadcasting the detection to a receiver. The chemical may be a drug of abuse. The device which is attached to the skin of a subject contains labeled antibodies or label containing microspheres attached to antibodies. The labeled antibodies are bound to solid phase drug via antigen-antibody interaction. These labeled antibodies are displaced from the solid phase support to which they are bound by free drug molecules in the perspiration. These labeled antibodies then migrate through a spacer layer and are trapped by a layer containing a suitable selective binding material. The label is illuminated or excited by a light source and detected by a photodetector. The signal can be recorded, or transmitted to a remote radio monitor.
    Type: Grant
    Filed: December 19, 1996
    Date of Patent: April 6, 1999
    Assignee: California Institute of Technology
    Inventors: David A. Kidwell, Gil F. Richards, Roger G. Kern, Frederick W. Mintz
  • Synthetic analog of sialic Lewis antigen from bacterial capsular polysaccharide
    Patent number: 5861505
    Abstract: An analog of sialic Lewis antigen prepared from native capsular polysaccharide of Klebsiella 63 bacteria.
    Type: Grant
    Filed: October 1, 1996
    Date of Patent: January 19, 1999
    Assignee: California Institute of Technology
    Inventor: Roger G. Kern
  • Structurally altered capsular polysaccharides produced by mutant bacteria
    Patent number: 5432066
    Abstract: Structurally altered capsular polysaccharides are produced by mutant bacteria. These polysaccharides are isolated by selecting a wild type bacterial strain and a phage producing degradative enzymes that have substrate specificity for the capsular polysaccharides produced by the wild type bacteria. Phage-resistant mutants producing capsular polysaccharides are selected and the structurally altered capsular polysaccharide is isolated therefrom.
    Type: Grant
    Filed: June 10, 1994
    Date of Patent: July 11, 1995
    Assignee: California Institute of Technology, Jet Propulsion Laboratory
    Inventors: Roger G. Kern, Gene R. Petersen, Gil F. Richards
  • Method for producing capsular polysaccharides
    Patent number: 5330903
    Abstract: Structurally altered capsular polysaccharides are produced by mutant bacteria. These polysaccharides are isolated by selecting a wild type bacterial strain and a phage producing degradative enzymes that have substrate specificity for the capsular polysaccharides produced by the wild type bacteria. Phage-resistant mutants producing capsular polysaccharides are selected and the structurally altered capsular polysaccharide is isolated therefrom.
    Type: Grant
    Filed: November 27, 1991
    Date of Patent: July 19, 1994
    Assignee: California Institute of Technology
    Inventors: Roger G. Kern, Gene R. Petersen, Gil F. Richards