Patents by Inventor Roger G. Ptak

Roger G. Ptak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-hydroxymethylcyclopropylidene methylpurines and -pyrimidines as antiviral agents
    Patent number: 6958345
    Abstract: Compounds which are active against viruses have the following Formulas: wherein B is a purine or pyrimidine heterocyclic ring and is preferably selected from the group consisting of 6-aminopurine (adenine), 2,6-diaminopurine, 2-amino-6-azidopurine, 2-amino-6-cyclopropylaminopurine, 6-hydroxypurine (hypoxanthine), 2-amino-6-halo substituted purines, 2-amino-6-alkoxy substituted purines, 2-amino-6-hydroxypurine (guanine), 3-deazapurines, 7-deaza-purines, 8-azapurines, cytosine, 5-halo substituted cytosines, 5-alkyl substituted cytosines, thymine, uracil and 6-azapyrimidines; X is O; and, R1 and R2 are alkyl or aryl groups. The compounds of the present invention also include the R- and S-enantiomers of the above compounds. The R1X and/or R2X can also be amino acid residues with X as NH.
    Type: Grant
    Filed: August 6, 2004
    Date of Patent: October 25, 2005
    Assignees: The Regents of the University of Michigan, Wayne State University
    Inventors: Jiri Zemlicka, Yao-Ling Qiu, John C. Drach, Roger G. Ptak
  • 2-hydroxymethylcyclopropylidenemethylpurines and -pyrimidines as antiviral agents
    Patent number: 6790841
    Abstract: Compounds which are active against viruses have the following Formulas: wherein B is a purine or pyrimidine heterocyclic ring and is preferably selected from the group consisting of 6-aminopurine (adenine), 2,6-diaminopurine, 2-amino-6-azidopurine, 2-amino-6-cyclopropylaminopurine, 6-hydroxypurine (hypoxanthine), 2-amino-6-halo substituted purines, 2-amino-6-alkoxy substituted purines, 2-amino-6-hydroxypurine (guanine), 3-deazapurines, 7-deaza-purines, 8-azapurines, cytosine, 5-halo substituted cytosines, 5-alkyl substituted cytosines, thymine, uracil and 6-azapyrimidines; X is O; and, R1 and R2 are alkyl or aryl groups. The compounds of the present invention also include the R- and S-enantiomers of the above compounds. The R1X and/or R2X can also be amino acid residues with X as NH.
    Type: Grant
    Filed: January 14, 2002
    Date of Patent: September 14, 2004
    Assignees: Wayne State University, The Regents of the University of Michigan
    Inventors: Jiri Zemlicka, Yao-Ling Qiu, John C. Drach, Roger G. Ptak
  • 2-hydroxymethylcyclopropylidenemethylpurines and -pyrimidines as antiviral agents
    Publication number: 20020193353
    Abstract: Compounds which are active against viruses have the following Formulas: 1
    Type: Application
    Filed: January 14, 2002
    Publication date: December 19, 2002
    Applicant: Wayne State University
    Inventors: Jiri Zemlicka, Yao-Ling Qiu, John C. Drach, Roger G. Ptak
  • 2-hydroxymethylcyclopropylidenemethylpurines and -pyrimidines as antiviral agents
    Patent number: 6352991
    Abstract: Compounds which are active against viruses have the following Formulas: wherein B is a purine or pyrimidine heterocyclic ring and is preferably selected from the group consisting of 6-aminopurine (adenine), 2,6-diaminopurine, 2-amino-6-azidopurine, 2-amino-6-cyclopropylaminopurine, 6-hydroxypurine (hypoxanthine), 2-amino-6-halo substituted purines, 2-amino-6-alkoxy substituted purines, 2-amino-6-hydroxypurine (guanine), 3-deazapurines, 7-deaza-purines, 8-azapurines, cytosine, 5-halo substituted cytosines, 5-alkyl substituted cytosines, thymine, uracil and 6-azapyrimidines; X is O; and, R1 and R2 are alkyl or aryl groups. The compounds of the present invention also include the R- and S-enantiomers of the above compounds. The R1X and/or R2X can also be amino acid residues with X as NH.
    Type: Grant
    Filed: March 12, 1999
    Date of Patent: March 5, 2002
    Assignees: Wayne State University, The Regents of the University of Michigan
    Inventors: Jiri Zemlicka, Yao-Ling Qiu, John C. Drach, Roger G. Ptak