Abstract: A display system includes a display screen, a light source to generate a light beam to be modulated in accordance with image data, and a beam scanning module to receive the light beams and to direct the light beam onto an associated display region of the display screen. The beam scanning module includes a resonant scanning mirror configured to scan the light beam along a first scanning direction across the associated display region, and a polygon scanning mirror to scan the light beam along a second scanning direction across the associated display region.

Abstract: A display system includes a display screen, a light source to generate a light beam to be modulated in accordance with image data, and a beam scanning module to receive the light beams and to direct the light beam onto an associated display region of the display screen. The beam scanning module includes a resonant scanning mirror configured to scan the light beam along a first scanning direction across the associated display region, and a polygon scanning mirror to scan the light beam along a second scanning direction across the associated display region.

Abstract: The present invention relates to methods of administration of rAAV vectors in a single administration method comprising a series of sub-administrations of sub-doses of rAAV vectors. The present invention also relates to rAAV vectors comprising cardiac-specific promoters, cardiac-cell specific promoters, multi-cell cardiac specific promoters, and elements thereof. The invention also relates to rAAV vectors, pharmaceutical compositions and uses thereof in methods for treating cardiovascular disease, heart diseases and heart failure in subjects in need thereof.

Abstract: A display system includes a display screen, a light source to generate a light beam to be modulated in accordance with image data, and a beam scanning module to receive the light beams and to direct the light beam onto an associated display region of the display screen. The beam scanning module includes a resonant mirror configured to scan the light beam along a first scanning direction across the associated display region, and a linear scanning mirror to scan the light beam along a second scanning direction across the associated display region. The beam scanning module also includes an integral fold mirror positioned to reflect the light beam from the light source to the resonant mirror.

Abstract: A display system includes a display screen, a light source to generate a light beam to be modulated in accordance with image data, and a beam scanning module to receive the light beams and to direct the light beam onto an associated display region of the display screen. The beam scanning module includes a resonant scanning mirror configured to scan the light beam along a first scanning direction across the associated display region, and a polygon scanning mirror to scan the light beam along a second scanning direction across the associated display region.

Abstract: A display system includes a display screen with at least one servo feedback mark in each of a plurality of display regions, and a plurality of subsystems each subsystem configured to generate an image on an associated display region. Each subsystem generate a plurality of scanning beams including an excitation beam and a servo beam, a beam scanning module, a servo feedback detector, and a controller. The beam scanning module includes a resonant scanning mirror configured to scan the scanning beams along a first scanning direction and a linear scanning mirror to scan the scanning beams along a second scanning direction. The controller is configured to receive image data, to modulate the excitation beam in accordance with the image data, and to control timing of modulation of the excitation beam based on the monitor signal to align the modulation with corresponding pixel positions on the display screen.

Abstract: A display system includes a display screen with at least one servo feedback mark in each of a plurality of display regions, and a plurality of subsystems each subsystem configured to generate an image on an associated display region. Each subsystem generate a plurality of scanning beams including an excitation beam and a servo beam, a beam scanning module, a servo feedback detector, and a controller. The beam scanning module includes a resonant scanning mirror configured to scan the scanning beams along a first scanning direction and a linear scanning mirror to scan the scanning beams along a second scanning direction. The controller is configured to receive image data, to modulate the excitation beam in accordance with the image data, and to control timing of modulation of the excitation beam based on the monitor signal to align the modulation with corresponding pixel positions on the display screen.

Abstract: A display system includes a display screen with at least one servo feedback mark in each of a plurality of display regions, and a plurality of subsystems each subsystem configured to generate an image on an associated display region. Each subsystem generate a plurality of scanning beams including an excitation beam and a servo beam, abeam scanning module, a servo feedback detector, and a controller. The beam scanning module includes a resonant scanning mirror configured to scan the scanning beams along a first scanning direction and a linear scanning mirror to scan the scanning beams along a second scanning direction. The controller is configured to receive image data, to modulate the excitation beam in accordance with the image data, and to control timing of modulation of the excitation beam based on the monitor signal to align the modulation with corresponding pixel positions on the display screen.

Abstract: A display system includes a display screen with at least one servo feedback mark in each of a plurality of display regions, and a plurality of subsystems each subsystem configured to generate an image on an associated display region. Each subsystem generate a plurality of scanning beams including an excitation beam and a servo beam, abeam scanning module, a servo feedback detector, and a controller. The beam scanning module includes a resonant scanning mirror configured to scan the scanning beams along a first scanning direction and a linear scanning mirror to scan the scanning beams along a second scanning direction. The controller is configured to receive image data, to modulate the excitation beam in accordance with the image data, and to control timing of modulation of the excitation beam based on the monitor signal to align the modulation with corresponding pixel positions on the display screen.

Abstract: Provided are SUMO activators, which can enhance SUMOylation of SERCA2a, which are useful in the treatment of heart failure, cardiovascular diseases, cancer, neurodegenerative disorders, viral infection, bacterial infection, liver disease, inflammation, and other diseases.

Abstract: A display system includes a display screen, a light source to generate a light beam to be modulated in accordance with image data, and a beam scanning module to receive the light beams and to direct the light beam onto an associated display region of the display screen. The beam scanning module includes a resonant scanning mirror configured to scan the light beam along a first scanning direction across the associated display region, and a polygon scanning mirror to scan the light beam along a second scanning direction across the associated display region.

Abstract: A scanning beam display system includes an optical module, an image control module, and a display screen on which optical beams are scanned. The optical module includes a vertical adjuster placed in the optical paths of the beams to control and adjust positions of the optical beams along a generally vertical direction on the display screen, and a control unit configured to receive control instructions for the vertical adjuster and to control the vertical adjuster to be at one of a predetermined number of orientations to place the scanning optical beams at a corresponding distinct position on the display screen. The control unit is further configured to apply an adjustment offset to each orientation of the vertical adjuster such that each immediately vertically adjacent pair of beam footprints projected on the display screen resulting from the plurality of positions have a vertical overlap that is larger than a first threshold.

Abstract: In one embodiment, the modular display includes aggregates of individual panel tiles arranged between two large plastic sheets. The footprint of the large plastic sheet sandwich becomes the dimension of the display screen. The tilettes are phosphor emission panels with a full complement of emittable pixels. By separating the tilettes from the final full dimension sheet, the tilettes can be manufactured in transportable sizes and the outer full dimension sheets can be rolled for easy transport to the final install location.

Abstract: Implementations described herein generally relate to scanning beam display systems and more specifically, to systems and methods for improved image alignment of such scanning beam display systems. The method comprises providing a display system comprising a display screen having a plurality of display screen region each with a corresponding light engine module having a servo laser beam and an excitation laser beam, scanning the servo laser beam of a light engine module in an outer scanning region outside of the light engine module's corresponding display screen region, detecting servo laser beam feedback light to measure an alignment error of the light engine module relative to the light engine module's corresponding display screen region, and adjusting alignment of the excitation laser beam based on the measured alignment error.

Abstract: A scanning beam display system includes an optical module, an image control module, and a display screen on which optical beams are scanned. The optical module includes a vertical adjuster placed in the optical paths of the beams to control and adjust positions of the optical beams along a generally vertical direction on the display screen, and a control unit configured to receive control instructions for the vertical adjuster and to control the vertical adjuster to be at one of a predetermined number of orientations to place the scanning optical beams at a corresponding distinct position on the display screen. The control unit is further configured to apply an adjustment offset to each orientation of the vertical adjuster such that each immediately vertically adjacent pair of beam footprints projected on the display screen resulting from the plurality of positions have a vertical overlap that is larger than a first threshold.

Abstract: A multi-layer display screen capable of being tiled without a visible gap between tiled screens and methods of using said device are described herein. In one embodiment, a system includes a light generator configured to produce light and a multi-layer screen with a plurality of layers. The multi-layer screen can be configured to permit the light from the light generator to propagate therethrough. The plurality of layers can include an opaque region layer having a plurality of opaque regions and a first layer comprising one or more abutted layers disposed within a common plane, the abutted layers spaced apart by a gap, wherein the gap is coincident with the opaque region.

Abstract: A scanning beam display system includes an optical module, an image control module, and a display screen on which optical beams are scanned. The optical module includes a vertical adjuster placed in the optical paths of the beams to control and adjust positions of the optical beams along a generally vertical direction on the display screen, and a control unit configured to receive control instructions for the vertical adjuster and to control the vertical adjuster to be at one of a predetermined number of orientations to place the scanning optical beams at a corresponding distinct position on the display screen. The control unit is further configured to apply an adjustment offset to each orientation of the vertical adjuster such that each immediately vertically adjacent pair of beam footprints projected on the display screen resulting from the plurality of positions have a vertical overlap that is larger than a first threshold.

Abstract: Implementations described herein generally relate to scanning beam display systems and more specifically, to systems and methods for improved image alignment of such scanning beam display systems. The method comprises providing a display system comprising a display screen having a plurality of display screen region each with a corresponding light engine module having a servo laser beam and an excitation laser beam, scanning the servo laser beam of a light engine module in an outer scanning region outside of the light engine module's corresponding display screen region, detecting servo laser beam feedback light to measure an alignment error of the light engine module relative to the light engine module's corresponding display screen region, and adjusting alignment of the excitation laser beam based on the measured alignment error.

Abstract: Implementations described herein generally relate to scanning beam display systems and more specifically, to systems and methods for improved image alignment of such scanning beam display systems. The method comprises providing a display system comprising a display screen having a plurality of display screen region each with a corresponding light engine module having a servo laser beam and an excitation laser beam, scanning the servo laser beam of a light engine module in an outer scanning region outside of the light engine module's corresponding display screen region, detecting servo laser beam feedback light to measure an alignment error of the light engine module relative to the light engine module's corresponding display screen region, and adjusting alignment of the excitation laser beam based on the measured alignment error.

Abstract: Systems and techniques for scanning-beam display are provided to use local dimming on the optical energy of at least one optical beam to minimize the non-uniform image brightness across the screen. This local dimming during the beam scanning can be achieved by adjusting optical energy of at least one optical beam during the scanning based on (1) the location of the scanning optical beam and (2) the predetermined distortion information at the location.