Patents by Inventor Roger Hanselmann

Roger Hanselmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof
    Patent number: 10150734
    Abstract: Provided herein are solid forms comprising 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, methods of making the solid forms, methods of their use for the treatment of various diseases and/or disorders and pharmaceutical compositions comprising the solid forms.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: December 11, 2018
    Assignee: Akebia Therapeutics, Inc.
    Inventors: Roger Hanselmann, Anne Luong
  • DEUTERIUM-ENRICHED HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE ENZYME INHIBITORS
    Publication number: 20180065933
    Abstract: Provided herein are deuterium-enriched compounds of Formula (I), Formula (II), Formula (III), Formula (IV), Formula (V), and Formula (VI). Pharmaceutical compositions comprising the isotope-enriched compounds, and methods of using such compounds are also provided.
    Type: Application
    Filed: March 18, 2016
    Publication date: March 8, 2018
    Applicant: Akebia Therapeutics, Inc.
    Inventor: Roger HANSELMANN
  • Biaryl heterocyclic compounds and methods of making and using the same
    Patent number: 9550783
    Abstract: The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of compounds having both a biaryl moiety and at least one heterocylic moiety that are useful as such agents.
    Type: Grant
    Filed: May 19, 2014
    Date of Patent: January 24, 2017
    Assignee: MELINTA THERAPEUTICS, INC.
    Inventors: Jiacheng Zhou, Ashoke Bhattacharjee, Shili Chen, Yi Chen, Jay J. Farmer, Joel A. Goldberg, Roger Hanselmann, Rongliang Lou, Alia Orbin, Adegboyega K. Oyelere, Joseph M. Salvino, Dane M. Springer, Jennifer Tran, Deping Wang, Yusheng Wu
  • SOLID FORMS OF 2-(5-(3-FLUOROPHENYL)-3-HYDROXYPICOLINAMIDO)ACETIC ACID, COMPOSITIONS, AND USES THEREOF
    Publication number: 20160214939
    Abstract: Provided herein are solid forms comprising 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, methods of making the solid forms, methods of their use for the treatment of various diseases and/or disorders and pharmaceutical compositions comprising the solid forms.
    Type: Application
    Filed: January 22, 2016
    Publication date: July 28, 2016
    Inventors: ROGER HANSELMANN, ANNE LUONG
  • Process for the synthesis of triazoles
    Patent number: 9376400
    Abstract: The present invention relates to processes for the preparation of triazoles. These compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.
    Type: Grant
    Filed: July 7, 2014
    Date of Patent: June 28, 2016
    Assignee: MELINTA THERAPEUTICS, INC.
    Inventors: Shili Chen, Rongliang Lou, Yusheng Wu, Jiacheng Zhou, Roger Hanselmann
  • Crystalline Forms of D-Glucitol, 1-Deoxy-1-(Methylamino)-, 1-(6-Amino-3,5-Difluoropyridine-2-Yl)-8-Chloro-6-Fluoro-1,4-Dihydro-7-(3-Hydroxyazetidin-1-Yl)-4-Oxo-3-Quinolinecarboxylate
    Publication number: 20160046603
    Abstract: The present disclosure relates generally to crystalline forms of anhydrous D-glucitol, 1-deoxy-1-(methylamino)-, 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxyazetidin-1- yl)-4-oxo-3-quinolinecarboyxlate, compositions comprising the same, and methods of making the same. Delafloxacin is an fluoroquinolone antibiotic with the chemical structure and the chemical name 1-deoxy-1-(methylamino)-, 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxyazetidin-1-yl)-4-oxo-3-quinolinecarboyxlate. Studies have indicated the existence of three anhydrous polymorphs of delafloxacin, as well as a trihydrate and methanol and ethanol solvates.
    Type: Application
    Filed: March 7, 2014
    Publication date: February 18, 2016
    Inventors: Roger HANSELMANN, Maxwell M. REEVE
  • Process for the Synthesis of Triazoles
    Publication number: 20150158827
    Abstract: The present invention relates to processes for the preparation of triazoles. These compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.
    Type: Application
    Filed: July 7, 2014
    Publication date: June 11, 2015
    Inventors: Shili Chen, Rongliang Lou, Yusheng Wu, Jiacheng Zhou, Roger Hanselmann
  • BIARYL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20150072970
    Abstract: The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of compounds having both a biaryl moiety and at least one heterocylic moiety that are useful as such agents.
    Type: Application
    Filed: May 19, 2014
    Publication date: March 12, 2015
    Applicant: MELINTA THERAPEUTICS, INC.
    Inventors: Jiacheng Zhou, Ashoke Bhattacharjee, Shili Chen, Yi Chen, Jay J. Farmer, Joel A. Goldberg, Roger Hanselmann, Rongliang Lou, Alia Orbin, Adegboyega K. Oyelere, Joseph M. Salvino, Dane M. Springer, Jennifer Tran, Deping Wang, Yusheng Wu
  • Process for the synthesis of biaryl oxazolidinones
    Patent number: 8895741
    Abstract: The present invention relates to processes for the preparation of biaryl oxazolidinones. These compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: November 25, 2014
    Assignee: Melinta Therapeutics, Inc.
    Inventors: Yusheng Wu, Shili Chen, Yi Chen, Roger Hanselmann, Rongliang Lou, Jiacheng Zhou
  • Process for making quinolone compounds
    Patent number: 8871938
    Abstract: The present invention relates to the field of synthesizing anti-infective compounds. More particularly, the invention relates to synthesizing a family of quinolone compounds useful as anti-infective agents. The invention includes a process for preparing a quinolone compound wherein less than about 0.40% of dimeric impurity of the quinolone is produced.
    Type: Grant
    Filed: July 9, 2013
    Date of Patent: October 28, 2014
    Assignee: Melinta Therapeutics, Inc.
    Inventors: Roger Hanselmann, Maxwell M. Reeve, Graham Johnson
  • Process for the syntheses of triazoles
    Patent number: 8796465
    Abstract: The present invention relates to processes for the preparation of triazoles. These compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: August 5, 2014
    Assignee: Melinta Therapeutics, Inc.
    Inventors: Shili Chen, Rongliang Lou, Yusheng Wu, Jiacheng Zhou, Roger Hanselmann
  • PROCESS FOR MAKING QUINOLONE COMPOUNDS
    Publication number: 20140171648
    Abstract: The present invention relates to the field of synthesizing anti-infective compounds. More particularly, the invention relates to synthesizing a family of quinolone compounds useful as anti-infective agents. The invention includes a process for preparing a quinolone compound wherein less than about 0.40% of dimeric impurity of the quinolone is produced.
    Type: Application
    Filed: July 9, 2013
    Publication date: June 19, 2014
    Inventors: Roger HANSELMANN, Maxwell M. REEVE, Graham JOHNSON
  • Process for the Syntheses of Triazoles
    Publication number: 20140031402
    Abstract: The present invention relates to processes for the preparation of triazoles. These compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.
    Type: Application
    Filed: March 18, 2013
    Publication date: January 30, 2014
    Applicant: RIB-X PHARMACEUTICALS, INC.
    Inventors: Shili Chen, Rongliang Lou, Yusheng Wu, Jiacheng Zhou, Roger Hanselmann
  • Process for making quinolone compounds
    Patent number: 8497378
    Abstract: The present invention relates to the field of synthesizing anti-infective compounds. More particularly, the invention relates to synthesizing a family of quinolone compounds useful as anti-infective agents. The invention includes a process for preparing a quinolone compound wherein less than about 0.40% of dimeric impurity of the quinolone is produced.
    Type: Grant
    Filed: September 23, 2009
    Date of Patent: July 30, 2013
    Assignee: Rib-X Pharmaceuticals, Inc.
    Inventors: Roger Hanselmann, Maxwell M. Reeve, Graham Johnson
  • Process for the synthesis of triazoles
    Patent number: 8399660
    Abstract: The present invention relates to processes for the preparation of triazoles. These compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.
    Type: Grant
    Filed: June 8, 2006
    Date of Patent: March 19, 2013
    Assignee: Rib-X Pharmaceuticals, Inc.
    Inventors: Shili Chen, Rongliang Lou, Yusheng Wu, Jiacheng Zhou, Roger Hanselmann
  • Process for the Synthesis of Biaryl Oxazolidinones
    Publication number: 20130066076
    Abstract: The present invention relates to processes for the preparation of biaryl oxazolidinones. These compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.
    Type: Application
    Filed: September 14, 2012
    Publication date: March 14, 2013
    Inventors: Yusheng Wu, Shili Chen, Yi Chen, Roger Hanselmann, Rongliang Lou, Jiacheng Zhou
  • Process for the synthesis of biaryl oxazolidinones
    Patent number: 8324398
    Abstract: The present invention relates to processes for the preparation of biaryl oxazolidinones. These compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.
    Type: Grant
    Filed: July 28, 2004
    Date of Patent: December 4, 2012
    Assignee: Rib-X Pharmaceuticals, Inc.
    Inventors: Yusheng Wu, Shili Chen, Yi Chen, Roger Hanselmann, Rongliang Lou, Jiacheng Zhou
  • PROCESS FOR MAKING QUINOLONE COMPOUNDS
    Publication number: 20120041208
    Abstract: The present invention relates to the field of synthesizing anti-infective compounds. More particularly, the invention relates to synthesizing a family of quinolone compounds useful as anti-infective agents. The invention includes a process for preparing a quinolone compound wherein less than about 0.40% of dimeric impurity of the quinolone is produced.
    Type: Application
    Filed: September 23, 2009
    Publication date: February 16, 2012
    Applicant: RIB-X PHARMACEUTICALS, INC.
    Inventors: Roger Hanselmann, Maxwell M. Reeve, Graham Johnson
  • Biaryl Heterocyclic Compounds And Methods Of Making And Using The Same
    Publication number: 20120010200
    Abstract: The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of compounds having both a biaryl moiety and at least one heterocylic moiety that are useful as such agents.
    Type: Application
    Filed: September 22, 2011
    Publication date: January 12, 2012
    Inventors: Jiacheng Zhou, Ashoke Bhattacharjee, Shili Chen, Yi Chen, Jay J. Farmer, Joel A. Goldberg, Roger Hanselmann, Rongliang Lou, Alia Orbin, Adegboyega K. Oyelere, Joseph M. Salvino, Dane M. Springer, Jennifer Tran, Deping Wang, Yusheng Wu
  • Process for making quinolone compounds
    Patent number: RE46617
    Abstract: The present invention relates to the field of synthesizing anti-infective compounds. More particularly, the invention relates to synthesizing a family of quinolone compounds useful as anti-infective agents. The invention includes a process for preparing a quinolone compound wherein less than about 0.40% of dimeric impurity of the quinolone is produced.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: November 28, 2017
    Assignee: MELINTA THERAPEUTICS, INC.
    Inventors: Roger Hanselmann, Maxwell M. Reeve, Graham Johnson