Patents by Inventor Roger Harper
Roger Harper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220288875Abstract: A method of moulding includes positioning a fibre between a hard mould face and flexible contra mould face, sealing the space between the two mould faces, deforming the flexible contra mould face to produce a channel, introducing a thermosetting resin into the space between the two mould faces, and returning the flexible contra mould face to its undeformed condition before the onset of resin gel.Type: ApplicationFiled: February 16, 2022Publication date: September 15, 2022Inventor: Alan Roger Harper
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Publication number: 20170341319Abstract: A method of moulding includes placing reinforcing fibre between a mould surface and a flexible diaphragm, and causing upward movement of the diaphragm to produce a resin flow channel along which resin is caused to flow.Type: ApplicationFiled: May 31, 2017Publication date: November 30, 2017Inventor: Alan Roger Harper
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Patent number: 7938018Abstract: A liquid flow sensing system for sensing the flow of liquid within a supply line (2) of a metering pumping machine, the system including a magnetic member (4) arranged for movement relative to a pneumatic switch (8) operated by the presence or absence of a magnetic field, the magnetic member (4) being contained within a sealed unit (5) located within the supply line (2) and the arrangement being such that, when the liquid flow rate falls below a predetermined level, the magnetic member (4) moves downwardly from a first operative position into a second operative position.Type: GrantFiled: April 23, 2009Date of Patent: May 10, 2011Assignee: GSSC, Inc.Inventor: Alan Roger Harper
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Patent number: 7833712Abstract: Methods are provided for detecting a cell proliferative disorder associated with TSLC1 by contacting a proliferating cell of a subject suspected of having the disorder with a reagent that detects TSLC1 and detecting the level of TSLC1 in the proliferating cell. TSLC1 is a single gene whose expression is reduced or absent in A549 and some other NSCLC, hepatocellular carcinoma and pancreatic cancer cell lines. It has further been discovered that TSLC1 expression or suppression is perfectly correlated with promoter methylation state. Restoration of TSLC1 expression to normal or higher levels is sufficient by itself to suppress tumor formation. The invention further provides methods of treating such disorders by contacting cells of a patient suffering from the disorder with a therapeutically effective amount of a reagent that modulates TSLC1 level in the proliferating cells.Type: GrantFiled: September 18, 2006Date of Patent: November 16, 2010Assignees: The John Hopkins University School of Medicine, National Cancer Center Research InstituteInventors: Roger Harper Reeves, Yoshinori Murakami
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Publication number: 20100230860Abstract: A sensing system is provided for sensing the pressure of liquid in a vacuum chamber (7). The system includes a pneumatic microswitch (14) having an operating element (15) arranged for movement in response to movement of a diaphragm (10) operated by a change in pressure and a plate means (16) in contact with the diaphragm (10) and with the operating element (15).Type: ApplicationFiled: March 12, 2010Publication date: September 16, 2010Inventor: Alan Roger Harper
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Patent number: 7745497Abstract: An electrically neutral composition in the form of a water-in-oil or an oil-in-water emulsion is imparted with a unipolar electrostatic charge on spraying from an aerosol spray device by incorporating into the composition a non-ionic surfactant and at least one polar or ionic or aromatic or linearly conjugated compound. The amount of the polar or ionic or aromatic or linearly conjugated compound included in the composition is about 0.01 to about 80% w/w based on the non-ionic surfactant, but is such that the theoretical conductivity of the emulsion is less than the bulk conductivity of the emulsion.Type: GrantFiled: March 5, 2002Date of Patent: June 29, 2010Assignees: Reckitt Benckiser (UK) Limited, Reckitt Benckiser (Australia) Pty LimitedInventors: Duncan Roger Harper, Neale Harrison, John Douglas Morgan, John Howard Clint, Mario Abela
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Publication number: 20100024566Abstract: A liquid flow sensing system for sensing the flow of liquid within a supply line (2) of a metering pumping machine, the system including a magnetic member (4) arranged for movement relative to a pneumatic switch (8) operated by the presence or absence of a magnetic field, the magnetic member (4) being contained within a sealed unit (5) located within the supply line (2) and the arrangement being such that, when the liquid flow rate falls below a predetermined level, the magnetic member (4) moves downwardly from a first operative position into a second operative position.Type: ApplicationFiled: April 23, 2009Publication date: February 4, 2010Inventor: Alan Roger Harper
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Publication number: 20090224929Abstract: A level sensing system for sensing the level of liquid in a container (19) includes a magnetic member (12) arranged for movement relative to a pneumatic switch (18) operated by the presence or absence of a magnetic field, a spring (13) acting on the magnetic member (12) and urging it towards a first operative position, and a weight (16) suspended from the magnetic member (12), the weight being positioned, in use, within the liquid in the container (19) such that, when the level of liquid in the container (19) falls to a predetermined level, the magnetic member (12) is caused to move from its first operative position (FIG. 1) into a second operative position (FIG. 2).Type: ApplicationFiled: March 9, 2009Publication date: September 10, 2009Inventor: Alan Roger Harper
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Patent number: 7438767Abstract: Cleaning compositions including a photocatalytic material and a sensitiser employ a photocatalytic material and a sensitiser at a locus, for example on a surface. The residue combats soils and/or undesired microorganisms at the locus. The addition of a monohydric or polyhydric alcohol, preferably having humectant properties, gives benefits in terms of smear avoidance on application and soil removal thereafter.Type: GrantFiled: June 27, 2002Date of Patent: October 21, 2008Assignee: Reckitt Benckiser (UK) LimitedInventors: Malcolm Tom Mckechnie, Duncan Roger Harper
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Patent number: 7153657Abstract: Methods are provided for detecting a cell proliferative disorder associated with TSLC1 by contacting a proliferating cell of a subject suspected of having the disorder with a reagent that detects TSLC1 and detecting the level of TSLC1 in the proliferating cell. TSLC1 is a single gene whose expression is reduced or absent in A549 and some other NSCLC, hepatocellular carcinoma and pancreatic cancer cell lines. It has further been discovered that TSLC1 expression or suppression is perfectly correlated with promoter methylation state. Restoration of TSLC1 expression to normal or higher levels is sufficient by itself to suppress tumor formation. The invention further provides methods of treating such disorders by contacting cells of a patient suffering from the disorder with a therapeutically effective amount of a reagent that modulates TSLC1 level in the proliferating cells.Type: GrantFiled: March 28, 2003Date of Patent: December 26, 2006Assignees: The Johns Hopkins University School of Medicine, National Cancer Center Research InstituteInventors: Roger Harper Reeves, Yoshinori Murakami
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Patent number: 7141125Abstract: Cleaning compositions including a photocatalytic material and a sensitiser employ a photocatalytic material and a sensitiser at a locus, for example on a surface. The residue combats soils and/or undesired microorganisms at the locus. The photocatalytic material is peroxo modified titania, preferably in its anatase form, or peroxo modified titanic acid, or a mixture thereof. The compositions are preferably alkaline.Type: GrantFiled: June 27, 2002Date of Patent: November 28, 2006Assignee: Reckitt Benckiser (UK) LimitedInventors: Malcolm Tom McKechnie, Duncan Roger Harper, Neil Campbell Muir
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Patent number: 7096730Abstract: An assembly that can be used in conjunction with a resin moulding apparatus includes means defining a chamber containing a pressure sensor, and an entry passage leading upwardly into the chamber. The arrangement is such that, when the assembly is mounted in an upper section of a mould and a moulding operation is being carried out, the resin enters the entry passage so that the level of resin in the entry passage increases producing an increase in the pressure within the chamber, and the configuration of the entry passage is such that the cross-sectional area thereof reduces with height.Type: GrantFiled: May 20, 2003Date of Patent: August 29, 2006Inventor: Alan Roger Harper
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Publication number: 20040266654Abstract: Cleaning compositions including a photocatalytic material and a sensitiser employ a photocatalytic material and a sensitiser at a locus, for example on a surface. The residue combats soils and/or undesired microorganisms at the locus. The addition of a monohydric or polyhydric alcohol, preferably having humectant properties, gives benefits in terms of smear avoidance on application and soil removal thereafter.Type: ApplicationFiled: July 19, 2004Publication date: December 30, 2004Inventors: Malcolm Tom Mckechnie, Duncan Roger Harper
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Publication number: 20040198625Abstract: Cleaning compositions including a photocatalytic material and a sensitiser employ a photocatalytic material and a sensitiser at a locus, for example on a surface. The residue combats soils and/or undesired microorganisms at the locus. The photocatalytic material is peroxo modified titania, preferably in its anatase form, or peroxo modified titanic acid, or a mixture thereof. The compositions are preferably alkaline.Type: ApplicationFiled: December 18, 2003Publication date: October 7, 2004Inventors: Malcolm Tom Mckechnie, Duncan Roger Harper, Neil Campbell Muir
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Publication number: 20040169300Abstract: An assembly that can be used in conjunction with a resin moulding apparatus includes means defining a chamber containing a pressure sensor, and an entry passage leading upwardly into the chamber. The arrangement is such that, when the assembly is mounted in an upper section of a mould and a moulding operation is being carried out, the resin enters the entry passage so that the level of resin in the entry passage increases producing an increase in the pressure within the chamber, and the configuration of the entry passage is such that the cross-sectional area thereof reduces with height.Type: ApplicationFiled: May 20, 2003Publication date: September 2, 2004Inventor: Alan Roger Harper
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Patent number: 6705791Abstract: A resin applicator comprises a roller mounted on a shank connected to a handgrip, and a hose for feeding the resin to the roller under the action of a prime mover. A normally open air bleed switch is positioned so that it is accessible to a thumb or finger of a hand holding the handgrip and is operable to control operation of the prime mover.Type: GrantFiled: July 23, 2002Date of Patent: March 16, 2004Inventor: Alan Roger Harper
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Patent number: 6645307Abstract: Cleaning compositions including a photocatalytic material and a sensitiser employ a photocatalytic material and a sensitiser at a locus, for example on a surface. The residue combats soils and/or undesired microorganisms at the locus.Type: GrantFiled: December 21, 2000Date of Patent: November 11, 2003Assignee: Reckitt Benckiser (UK) LimitedInventors: Rod Thomas Fox, Duncan Roger Harper
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Publication number: 20030165974Abstract: Methods are provided for detecting a cell proliferative disorder associated with TSLC1 by contacting a proliferating cell of a subject suspected of having the disorder with a reagent that detects TSLC1 and detecting the level of TSLC1 in the proliferating cell. TSLC1 is a single gene whose expression is reduced or absent in A549 and some other NSCLC, hepatocellular carcinoma and pancreatic cancer cell lines. It has further been discovered that TSLC1 expression or suppression is perfectly correlated with promoter methylation state. Restoration of TSLC1 expression to normal or higher levels is sufficient by itself to suppress tumor formation. The invention further provides methods of treating such disorders by contacting cells of a patient suffering from the disorder with a therapeutically effective amount of a reagent that modulates TSLC1 level in the proliferating cells.Type: ApplicationFiled: March 28, 2003Publication date: September 4, 2003Inventors: Roger Harper Reeves, Yoshinori Murakami
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Patent number: 6612510Abstract: A method of improving the spraying of liquid droplets from a spray device onto a surface which method comprises imparting a unipolar charge to the said liquid droplets by double layer charging during the spraying of the liquid droplets from the spray device, the unipolar charge being at a level such that the said droplets have a charge to mass ratio of at least ±1×10−4 C/kg, whereby the charged droplets of the liquid are mutually repelled thereby increasing the spread of the droplets from a central spray line extending from the head of the spray device and avoiding coalescence of the droplets, thus providing a more even coverage of the surface which is to be sprayed. In particular, the method enables liquid droplets to be sprayed onto a surface which is obscured by all object located between the surface and the spray device.Type: GrantFiled: June 8, 2001Date of Patent: September 2, 2003Assignees: University of Southampton, Reckitt Benckiser (UK) LimitedInventors: Rodney Thomas Fox, Neale Harrison, John Farrell Hughes, Duncan Roger Harper, Lindsey Faye Whitmore
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Patent number: 6596493Abstract: Methods are provided for detecting a cell proliferative disorder associated with TSLC1 by contacting a proliferating cell of a subject suspected of having the disorder with a reagent that detects TSLC1 and detecting the level of TSLC1 in the proliferating cell. TSLC1 is a single gene whose expression is reduced or absent in A549 and some other NSCLC, hepatocellular carcinoma and pancreatic cancer cell lines. It has further been discovered that TSLC1 expression or suppression is perfectly correlated with promoter methylation state. Restoration of TSLC1 expression to normal or higher levels is sufficient by itself to suppress tumor formation. The invention further provides methods of treating such disorders by contacting cells of a patient suffering from the disorder with a therapeutically effective amount of a reagent that modulates TSLC1 level in the proliferating cells.Type: GrantFiled: August 15, 2001Date of Patent: July 22, 2003Assignees: The Johns Hopkins University School of Medicine, National Cancer Center Research InstituteInventors: Roger Harper Reeves, Yoshinori Murakami