Patents by Inventor Roger Isaac
Roger Isaac has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11688488Abstract: An analytic method for improving the efficiency in identifying protein molecular effect information using low resolution x-ray crystallography, by selecting and imaging a protein sample with low resolution x-ray crystallography and assaying the data thus generated as to local ligand strain energy value, followed by calculating a real-space difference density Z for each element and compiling ZDD data therefrom, followed by determining the true protomer/tautomer state of the protein sample by calculating Scorei according to the following equation so that the highest Scorei signifies the molecular effect information: Scorei={((ZDDi??ZDD)/?ZDD)+((SEi??SE)/?SE)}.Type: GrantFiled: February 26, 2020Date of Patent: June 27, 2023Assignee: Quantumbio, Inc.Inventors: Lance Michael Westerhoff, Oleh Y. Borbulevych, Roger Isaac Martin
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Publication number: 20210407620Abstract: The invention is a diagnostic which overlays quantum mechanical analysis to x-ray crystallography or Cryo-EM data from one or more molecules, to assess and identify the real world conformation, protonation and solvent effects of one or more moieties in said molecule. This “overlay” occurs by scoring and identifying the protomer/tautomer or conformational states of the moieties using quantum mechanical analysis. The diagnostic results of the present invention accurately identify protein-ligand binding, rendered as an output to a user of a computer in which the x-ray crystallography or Cryo-EM data is analysed with semi-empirical Hamiltonian quantum mechanics.Type: ApplicationFiled: June 15, 2021Publication date: December 30, 2021Applicant: QuantumBio Inc.Inventors: Lance Michael Westerhoff, Oleh Y. Borbulevych, Roger Isaac Martin
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Publication number: 20200194096Abstract: An analytic method for improving the efficiency in identifying protein molecular effect information using low resolution x-ray crystallography, by selecting and imaging a protein sample with low resolution x-ray crystallography and assaying the data thus generated as to local ligand strain energy value, followed by calculating a real-space difference density Z for each element and compiling ZDD data therefrom, followed by determining the true protomer/tautomer state of the protein sample by calculating Scorei according to the following equation so that the highest Scorei signifies the molecular effect information: Scorei={((ZDDi??ZDD)/?ZDD)+((SEi??SE)/?SE)}.Type: ApplicationFiled: February 26, 2020Publication date: June 18, 2020Applicant: QuantumBio Inc.Inventors: Lance Michael Westerhoff, Oleh Y. Borbulevych, Roger Isaac Martin
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Patent number: 10614909Abstract: An analytic method for improving the efficiency in identifying protein molecular effect information using low resolution x-ray crystallography, by selecting and imaging a protein sample with low resolution x-ray crystallography and assaying the data thus generated as to local ligand strain energy value, followed by calculating a real-space difference density Z for each element and compiling ZDD data therefrom, followed by determining the true protomer/tautomer state of the protein sample by calculating Scorei according to the following equation so that the highest Scorei signifies the molecuar effect information: Scorei={((ZDDi ??ZDD)/?ZDD)+((SEi ??SE)/?SE)}.Type: GrantFiled: February 5, 2016Date of Patent: April 7, 2020Assignee: QuantumBio Inc.Inventors: Lance Michael Westerhoff, Oleh Y. Borbulevych, Roger Isaac Martin
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Patent number: 10523278Abstract: A computing device includes an integrated unit having a plurality of functional components, and an extremely high frequency (EHF) communication unit operatively coupled to the integrated unit. The EHF communication unit includes a transducer configured to transmit and receive EHF electromagnetic signals, and convert between electrical signals and electromagnetic signals. The computing device includes a transceiver operatively coupled to the transducer. The EHF communication unit may enable at least one of the functional components of the computing device to be supplemented by a functional component of an external computing device.Type: GrantFiled: June 15, 2018Date of Patent: December 31, 2019Assignee: Keyssa, Inc.Inventors: Gary D. McCormack, Roger Isaac, Ian A. Kyles
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Patent number: 10334082Abstract: An extremely high frequency (EHF) protocol converter may include a transducer, an EHF communication circuit, a protocol conversion circuit, and a circuit port. The transducer may be configured to convert between an electromagnetic EHF data signal and an electrical EHF signal. The EHF communication circuit may be configured to convert between a baseband data signal and the electrical EHF signal. The protocol conversion circuit may be adapted to convert between the baseband data signal having data formatted according to a first data protocol associated with a first external device and a second baseband data signal having data formatted according to a second data protocol associated with a second external device. The second data protocol may be different from the first data protocol. The circuit port may conduct the second baseband data signal to the second external device.Type: GrantFiled: October 25, 2017Date of Patent: June 25, 2019Assignee: Keyssa, Inc.Inventors: Gary D. McCormack, Roger Isaac, Eric Almgren
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Publication number: 20190103898Abstract: A computing device includes an integrated unit having a plurality of functional components, and an extremely high frequency (EHF) communication unit operatively coupled to the integrated unit. The EHF communication unit includes a transducer configured to transmit and receive EHF electromagnetic signals, and convert between electrical signals and electromagnetic signals. The computing device includes a transceiver operatively coupled to the transducer. The EHF communication unit may enable at least one of the functional components of the computing device to be supplemented by a functional component of an external computing device.Type: ApplicationFiled: June 15, 2018Publication date: April 4, 2019Inventors: Gary D. McCormack, Roger Isaac, Ian A. Kyles
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Publication number: 20190026421Abstract: The invention is a diagnostic which overlays quantum mechanical analysis to x-ray crystallography data from one or more proteins to assess and identify the real world conformation, protonation and solvent effects of one or more moieties in said protein. This “overlay” occurs by scoring and identifying the protomer/tautomer states of the moieties using quantum mechanical analysis.Type: ApplicationFiled: February 5, 2016Publication date: January 24, 2019Applicant: QuantumBio Inc.Inventors: Lance Michael Westerhoff, Oleh Y. Borbulevych, Roger Isaac Martin
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Patent number: 10097341Abstract: A device comprises a clock data recovery (CDR) circuit. The CDR circuit has an input node to receive an input data signal, an output node, a data recovery circuit, and a self-test circuit. The CDR circuit supports a first mode of operation and a second mode of operation. In the first mode, the CDR circuit receives the input data signal at the input node and provides the input data signal to an input of the data recovery circuit, the data recovery circuit recovers first data from the input data signal, and the CDR circuit provides the first data for output at the output node. In the second mode, the self-test circuit generates a test data pattern which is provided to the output node and looped back to the input of the data recovery circuit, the data recovery circuit recovers second data from the test data pattern, and the self-test circuit checks the second data for errors.Type: GrantFiled: August 30, 2017Date of Patent: October 9, 2018Assignee: Keyssa Systems, Inc.Inventors: Jerome Jean Ribo, Bruno Tourette, Roger Isaac
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Patent number: 10033439Abstract: A computing device includes an integrated unit having a plurality of functional components, and an extremely high frequency (EHF) communication unit operatively coupled to the integrated unit. The EHF communication unit includes a transducer configured to transmit and receive EHF electromagnetic signals, and convert between electrical signals and electromagnetic signals. The computing device includes a transceiver operatively coupled to the transducer. The EHF communication unit may enable at least one of the functional components of the computing device to be supplemented by a functional component of an external computing device.Type: GrantFiled: October 11, 2016Date of Patent: July 24, 2018Assignee: Keyssa, Inc.Inventors: Gary D. McCormack, Roger Isaac, Ian A. Kyles
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Patent number: 10031160Abstract: A test fixture has a flexible plastic cable that acts as a waveguide. The Device-Under-Test (DUT) is a small transceiver and antenna that operate in the Extremely High-Frequency (EHF) band of 30-300 GHz. The size of the DUT transceiver is very small, limiting the power of emitted electromagnetic radiation so that close-proximity communication is used. The envelope for reception may only extend for about a centimeter from the DUT transceiver, about the same size as the test socket. A slot is formed in the test socket very near to the antenna. The slot receives one end of the plastic waveguide. The slot extends into the envelope by the DUT transceiver so that close-proximity radiation is captured by the plastic waveguide. The waveguide has a high relative permittivity and reflective metalized walls so that the radiation may be carried to a receiver that is outside the envelope.Type: GrantFiled: October 10, 2017Date of Patent: July 24, 2018Assignee: Keyssa, Inc.Inventors: Roger Isaac, Bhupendra Sarhad, Gary Davis McCormack, Ian A. Kyles, Frederick George Weiss, Christopher Scott Sansom
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Publication number: 20180063293Abstract: An extremely high frequency (EHF) protocol converter may include a transducer, an EHF communication circuit, a protocol conversion circuit, and a circuit port. The transducer may be configured to convert between an electromagnetic EHF data signal and an electrical EHF signal. The EHF communication circuit may be configured to convert between a baseband data signal and the electrical EHF signal. The protocol conversion circuit may be adapted to convert between the baseband data signal having data formatted according to a first data protocol associated with a first external device and a second baseband data signal having data formatted according to a second data protocol associated with a second external device. The second data protocol may be different from the first data protocol. The circuit port may conduct the second baseband data signal to the second external device.Type: ApplicationFiled: October 25, 2017Publication date: March 1, 2018Inventors: Gary D. McCormack, Roger Isaac, Eric Almgren
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Publication number: 20180031606Abstract: A test fixture has a flexible plastic cable that acts as a waveguide. The Device-Under-Test (DUT) is a small transceiver and antenna that operate in the Extremely High-Frequency (EHF) band of 30-300 GHz. The size of the DUT transceiver is very small, limiting the power of emitted electromagnetic radiation so that close-proximity communication is used. The envelope for reception may only extend for about a centimeter from the DUT transceiver, about the same size as the test socket. A slot is formed in the test socket very near to the antenna. The slot receives one end of the plastic waveguide. The slot extends into the envelope by the DUT transceiver so that close-proximity radiation is captured by the plastic waveguide. The waveguide has a high relative permittivity and reflective metalized walls so that the radiation may be carried to a receiver that is outside the envelope.Type: ApplicationFiled: October 10, 2017Publication date: February 1, 2018Inventors: Roger Isaac, Bhupendra Sarhad, Gary Davis McCormack, Ian A. Kyles, Frederick George Weiss, Christopher Scott Sansom
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Patent number: 9832288Abstract: An extremely high frequency (EHF) protocol converter may include a transducer, an EHF communication circuit, a protocol conversion circuit, and a circuit port. The transducer may be configured to convert between an electromagnetic EHF data signal and an electrical EHF signal. The EHF communication circuit may be configured to convert between a baseband data signal and the electrical EHF signal. The protocol conversion circuit may be adapted to convert between the baseband data signal having data formatted according to a first data protocol associated with a first external device and a second baseband data signal having data formatted according to a second data protocol associated with a second external device. The second data protocol may be different from the first data protocol. The circuit port may conduct the second baseband data signal to the second external device.Type: GrantFiled: August 1, 2016Date of Patent: November 28, 2017Assignee: KEYSSA, INC.Inventors: Gary D. McCormack, Roger Isaac, Eric Almgren
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Patent number: 9817025Abstract: A test fixture has a flexible plastic cable that acts as a waveguide. The Device-Under-Test (DUT) is a small transceiver and antenna that operate in the Extremely High-Frequency (EHF) band of 30-300 GHz. The size of the DUT transceiver is very small, limiting the power of emitted electromagnetic radiation so that close-proximity communication is used. The envelope for reception may only extend for about a centimeter from the DUT transceiver, about the same size as the test socket. A slot is formed in the test socket very near to the antenna. The slot receives one end of the plastic waveguide. The slot extends into the envelope by the DUT transceiver so that close-proximity radiation is captured by the plastic waveguide. The waveguide has a high relative permittivity and reflective metalized walls so that the radiation may be carried to a receiver that is outside the envelope.Type: GrantFiled: February 9, 2017Date of Patent: November 14, 2017Assignee: Keyssa, Inc.Inventors: Roger Isaac, Bhupendra Sarhad, Gary Davis McCormack, Ian A. Kyles, Frederick George Weiss, Christopher Scott Sansom
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Publication number: 20170228495Abstract: The invention is a diagnostic which overlays quantum mechanical analysis to x-ray crystallography data from one or more proteins to assess and identify the real world conformation, protonation and solvent effects of one or more moieties in said protein. This “overlay” occurs by scoring and identifying the protomer/tautomer states of the moieties using quantum mechanical analysis.Type: ApplicationFiled: February 5, 2016Publication date: August 10, 2017Applicant: QuantumBio Inc.Inventors: Lance Michael Westerhoff, Oleh Y. Borgulevych, Roger Isaac Martin
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Publication number: 20170160310Abstract: A test fixture has a flexible plastic cable that acts as a waveguide. The Device-Under-Test (DUT) is a small transceiver and antenna that operate in the Extremely High-Frequency (EHF) band of 30-300 GHz. The size of the DUT transceiver is very small, limiting the power of emitted electromagnetic radiation so that close-proximity communication is used. The envelope for reception may only extend for about a centimeter from the DUT transceiver, about the same size as the test socket. A slot is formed in the test socket very near to the antenna. The slot receives one end of the plastic waveguide. The slot extends into the envelope by the DUT transceiver so that close-proximity radiation is captured by the plastic waveguide. The waveguide has a high relative permittivity and reflective metalized walls so that the radiation may be carried to a receiver that is outside the envelope.Type: ApplicationFiled: February 9, 2017Publication date: June 8, 2017Inventors: Roger Isaac, Bhupendra Sarhad, Gary Davis McCormack, Ian A. Kyles, Frederick George Weiss, Christopher Scott Sansom
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Patent number: 9588173Abstract: A test fixture has a flexible plastic cable that acts as a waveguide. The Device-Under-Test (DUT) is a small transceiver and antenna that operate in the Extremely High-Frequency (EHF) band of 30-300 GHz. The size of the DUT transceiver is very small, limiting the power of emitted electromagnetic radiation so that close-proximity communication is used. The envelope for reception may only extend for about a centimeter from the DUT transceiver, about the same size as the test socket. A slot is formed in the test socket very near to the antenna. The slot receives one end of the plastic waveguide. The slot extends into the envelope by the DUT transceiver so that close-proximity radiation is captured by the plastic waveguide. The waveguide has a high relative permittivity and reflective metalized walls so that the radiation may be carried to a receiver that is outside the envelope.Type: GrantFiled: December 17, 2013Date of Patent: March 7, 2017Assignee: Keyssa, Inc.Inventors: Roger Isaac, Bhupendra Sarhad, Gary Davis McCormack, Ian A. Kyles, Frederick George Weiss, Christopher Scott Sansom
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Publication number: 20170033841Abstract: A computing device includes an integrated unit having a plurality of functional components, and an extremely high frequency (EHF) communication unit operatively coupled to the integrated unit. The EHF communication unit includes a transducer configured to transmit and receive EHF electromagnetic signals, and convert between electrical signals and electromagnetic signals. The computing device includes a transceiver operatively coupled to the transducer. The EHF communication unit may enable at least one of the functional components of the computing device to be supplemented by a functional component of an external computing device.Type: ApplicationFiled: October 11, 2016Publication date: February 2, 2017Inventors: Gary D. McCormack, Roger Isaac, Ian A. Kyles
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Patent number: 9535115Abstract: A test fixture has a flexible plastic cable that acts as a waveguide. The Device-Under-Test (DUT) is a small transceiver and antenna that operate in the Extremely High-Frequency (EHF) band of 30-300 GHz. The size of the DUT transceiver is very small, limiting the power of emitted electromagnetic radiation so that close-proximity communication is used. The envelope for reception may only extend for about a centimeter from the DUT transceiver, about the same size as the test socket. A slot is formed in the test socket very near to the antenna. The slot receives one end of the plastic waveguide. The slot extends into the envelope by the DUT transceiver so that close-proximity radiation is captured by the plastic waveguide. The waveguide has a high relative permittivity and reflective metalized walls so that the radiation may be carried to a receiver that is outside the envelope.Type: GrantFiled: December 17, 2013Date of Patent: January 3, 2017Assignee: Keyssa, Inc.Inventors: Roger Isaac, Bhupendra Sarhad, Gary Davis McCormack, Ian A. Kyles, Frederick George Weiss