Patents by Inventor Roger Léger

Roger Léger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Long lasting growth hormone releasing factor derivatives
    Publication number: 20030073630
    Abstract: This invention relates to growth hormone releasing factor (GRF) derivatives. In particular, this invention relates to GRF peptide derivatives having an extended in vivo half-life, for promoting the endogenous production or release of growth hormone in humans and animals.
    Type: Application
    Filed: August 12, 2002
    Publication date: April 17, 2003
    Inventors: Dominique P. Bridon, Nissab Boudjellab, Roger Leger, Martin Robitaille, Lucie Jette, Corinne Benquet
  • Uridyl peptide antibiotic (UPA) derivatives, their synthesis and use
    Patent number: 6482921
    Abstract: The present invention relates to dihydro derivatives of the uridyl peptide antibiotics mureidomycin, pacidimycin and napsamycin which have antibiotic activity against a number of bacterial strains including strains resistant to current therapeutic antibiotics.
    Type: Grant
    Filed: June 11, 1999
    Date of Patent: November 19, 2002
    Assignee: Essential Therapeutics, Inc.
    Inventors: Constantine G. Boojamra, Rémy C. Lemoine, Scott Hecker, Ving J. Lee, Roger Léger
  • Hydrolytic enzyme substrates and assay method
    Patent number: 6455268
    Abstract: Compounds of the invention have the structure D—L—A*, where L is a linking moiety that maintains D and A in a configuration compatible with FRET, D is a fluorescent donor moiety capable of causing an acceptor moiety to fluoresce by FRET, and A* is a fluorescent acceptor moiety capable of accepting energy from the donor moiety by FRET and fluorescing only after cleavage of one or more labile groups to provide acceptor A. These compounds are useful as fluorescent substrates for detection of enzymes in vivo.
    Type: Grant
    Filed: November 3, 2000
    Date of Patent: September 24, 2002
    Assignee: Iconix Pharmaceuticals Inc.
    Inventors: Kurt Jarnigan, Roger Leger, Ving J. Lee, David Morgans
  • Peptidomimetic efflux pump inhibitors
    Patent number: 6436980
    Abstract: Compounds are described which have efflux pump inhibitor activity. Also described are methods of using such efflux pump inhibitor compounds and pharmaceutical compositions which include such compounds.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: August 20, 2002
    Assignee: Essential Therapeutics, Inc.
    Inventors: Roger Leger, Ving J. Lee, Miles She
  • Efflux pump inhibitors
    Patent number: 6399629
    Abstract: Compounds are described which have efflux pump inhibitor activity. Also described are methods of using such efflux pump inhibitor compounds and pharmaceutical compositions which include such compounds.
    Type: Grant
    Filed: July 1, 1998
    Date of Patent: June 4, 2002
    Assignee: Microcide Pharmaceuticals, Inc.
    Inventors: Suzanne Chamberland, Yohei Ishida, Ving J Lee, Roger Leger, Kiyoshi Nakayama, Toshiharu Ohta, Masami Ohtsuka, Thomas E. Renau, William J. Watkins, Zhijia J. Zhang
  • Efflux pump inhibitors
    Patent number: 6245746
    Abstract: Compounds are described which have efflux pump inhibitor activity. Also described are methods of using such efflux pump inhibitor compounds and pharmaceutical compositions which include such compounds.
    Type: Grant
    Filed: February 4, 1998
    Date of Patent: June 12, 2001
    Assignee: Microcide Pharmaceuticals, Inc.
    Inventors: Suzanne Chamberland, May Lee, Roger Leger, Ving J. Lee, Thomas Renau, Zhijia J. Zhang
  • Pacidamycins produced by Streptomyces coeruleorubidus
    Patent number: 6228842
    Abstract: The invention provides novel antibiotics of the pacidamycin group of uridyl peptide antibiotics and methods of preparing and using those compounds.
    Type: Grant
    Filed: November 6, 1998
    Date of Patent: May 8, 2001
    Assignee: Microcide Pharmaceuticals, Inc.
    Inventors: Richard Fronko, May Lee, Ving J. Lee, Roger Leger
  • Peptidomimetic efflux pump inhibitors
    Patent number: 6204279
    Abstract: Compounds are described which have efflux pump inhibitor activity. Also described are methods of using such efflux pump inhibitor compounds and pharmaceutical compositions which include such compounds.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: March 20, 2001
    Assignee: Microcide Pharmaceuticals, Inc.
    Inventors: Roger Leger, Ving J. Lee, Miles She
  • Efflux pump inhibitors
    Patent number: 6114310
    Abstract: Compounds are described which have efflux pump inhibitor activity. Also described are methods of using such efflux pump inhibitor compounds and pharmaceutical compositions which include such compounds.
    Type: Grant
    Filed: January 23, 1998
    Date of Patent: September 5, 2000
    Assignee: Microcide Pharmaceuticals, Inc.
    Inventors: Suzanne Chamberland, May Lee, Roger Leger, Ving J. Lee, Thomas Renau, Zhijia J. Zhang