Patents by Inventor Roger Lewis Whiting

Roger Lewis Whiting has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the treatment of neuronal damage associated with ischemia, hypoxia or neurodegeneration
    Patent number: 5733871
    Abstract: Intravenous administration and pharmaceutically acceptable compositions of neurotrophic factors for treating neuronal damage in the central nervous system of individuals in need of such treatment are disclosed. The neuronal damage associated with ischemia, hypoxia, or neurodegeneration may result from stroke or cardiac arrest. This invention provides for the intravenous administration of neurotrophic factors such as bFGF, aFGF, NGF, CNTF, BDNF, NT3, NT4, IGF-I and IGF-II.
    Type: Grant
    Filed: March 16, 1995
    Date of Patent: March 31, 1998
    Assignee: The General Hospital Corporation
    Inventors: Brian J. Alps, Christine Mary Brown, Franklin D. Collins, Caroline J. Emmett, Michael Spedding, Deborah Russell, Seth P. Finklestein, Michael A. Moskowitz, Roger Lewis Whiting
  • Benzocycloalkylazolethione derivatives and processes for preparing the same
    Patent number: 5719280
    Abstract: The present invention relates to novel benzocycloalkylazolethione compounds which are dopamine .beta.-hydroxylase inhibitors in which the benzocycloalkyl portion of the compound is selected from indanyl, 1,2,3,4-tetrahydronaphthalenyl and 6,7,8,9-tetrahydro-5H-benzocycloheptenyl (in which the benzo is optionally substituted with one to three substituents) and the azolethione portion of the compound is selected from 2-thioxo-2,3-dihydro-1H-imidazol-3-yl, 5-thioxo-4,5-dihydro-1H-?1,2,4!triazol-4-yl and 5-thioxo-4,5-dihydro-1H-?1,2,4!triazol-1-yl (each optionally substituted with one to three substituents); and the prodrugs, pharmaceutically acceptable salts, individual isomers and mixtures of isomers and the methods of using and preparing such benzocycloalkylazolethione compounds.
    Type: Grant
    Filed: April 7, 1997
    Date of Patent: February 17, 1998
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Gregory Ricardo Martinez, Owen Will Gooding, David Bruce Repke, Philip Jay Teitelbaum, Keith Adrian Murray Walker, Roger Lewis Whiting