Patents by Inventor Roger Malerbakken BJERKE

Roger Malerbakken BJERKE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LRRC15 ANTIBODIES AND CONJUGATES THEREOF
    Publication number: 20240108766
    Abstract: The present invention relates to conjugates comprising a chelator arranged for complexation of a radionuclide and a targeting moiety binding to LRRC15. For example, the conjugates according to the current invention can be targeted alpha therapeutics such as targeted thorium conjugates (TTCs), i.e. radioconjugates comprising an alpha emitter, such as 227Th. The present invention further relates to sequence-defined antibodies binding LRRC15 and antigen-binding fragments thereof. Also provided are conjugates comprising these antibodies or functional fragments thereof. The antibodies, functional fragments and conjugates according to the current invention can be used to treat cancer and other disorders and conditions associated with the expression of LRRC15.
    Type: Application
    Filed: January 17, 2022
    Publication date: April 4, 2024
    Inventors: Mark TRAUTWEIN, Urs Beat HAGEMANN, Phillipp ELLINGER, Stephan MAERSCH, Joachim SCHUHMACHER, Antje WENGNER, Roger Malerbakken BJERKE, Helge ROIDER