Patents by Inventor Roger Marquez ILAGAN

Roger Marquez ILAGAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENHANCEMENT OF MSC IMMUNOMODULATORY PROPERTIES BY TREPROSTINIL
    Publication number: 20230137713
    Abstract: Provided are methods for treating or preventing vasculopathy comprising administering to a subject in need thereof, ac composition comprising a mesenchymal stem cell (MSC), or a part of a culture medium that has been in contact with the MSC and comprises one or more components of the MSC, or an exosome derived from the MSC. Pharmaceutical compositions suitable for such treatment is also provided.
    Type: Application
    Filed: December 29, 2022
    Publication date: May 4, 2023
    Applicant: United Therapeutics Corporation
    Inventors: Roger Marquez ILAGAN, Sarah HOGAN, John B. CHEADLE
  • Enhancement of MSC immunomodulatory properties by treprostinil
    Patent number: 11571444
    Abstract: Provided are methods for treating or preventing vasculopathy comprising administering to a subject in need thereof , ac composition comprising a mesenchymal stem cell (MSC), or a part of a culture medium that has been in contact with the MSC and comprises one or more components of the MSC, or an exosome derived from the MSC. Pharmaceutical compositions suitable for such treatment is also provided.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: February 7, 2023
    Assignee: United Therapeutics Corporation
    Inventors: Roger Marquez Ilagan, Sarah Hogan, John B. Cheadle
  • EXTRACELLULAR VESICLES WITH ENHANCED POTENCY
    Publication number: 20210154238
    Abstract: Provided are methods for isolating potent extracellular vesicle or exosome populations from mesenchymal stromal cells, and the use of the isolated extracellular vesicles or exosomes in treating vasculopathy, including pulmonary hypertension, bronchopulmonary dysplasia, and disease and conditions associated with mitochondrial dysfunction.
    Type: Application
    Filed: February 1, 2021
    Publication date: May 27, 2021
    Applicant: United Therapeutics Corporation
    Inventors: Sarah HOGAN, Roger Marquez ILAGAN, Maria Pia RODRIGUEZ, Carolina MEDRANO, John CHEADLE
  • Extracellular vesicles with enhanced potency
    Patent number: 10946047
    Abstract: Provided are methods for isolating potent extracellular vesicle or exosome populations from mesenchymal stromal cells, and the use of the isolated extracellular vesicles or exosomes in treating vasculopathy, including pulmonary hypertension, bronchopulmonary dysplasia, and disease and conditions associated with mitochondrial dysfunction.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: March 16, 2021
    Assignee: United Therapeutics Corporation
    Inventors: Sarah Hogan, Roger Marquez Ilagan, Maria Pia Rodriguez, Carolina Medrano, John Cheadle
  • EXTRACELLULAR VESICLES WITH ENHANCED POTENCY
    Publication number: 20180296606
    Abstract: Provided are methods for isolating potent extracellular vesicle or exosome populations from mesenchymal stromal cells, and the use of the isolated extracellular vesicles or exosomes in treating vasculopathy, including pulmonary hypertension, bronchopulmonary dysplasia, and disease and conditions associated with mitochondrial dysfunction.
    Type: Application
    Filed: May 1, 2018
    Publication date: October 18, 2018
    Applicant: United Therapeutics Corporation
    Inventors: Sarah Hogan, Roger Marquez Ilagan, Maria Pia Rodriguez, Carolina Medrano, John Cheadle
  • ENHANCEMENT OF MSC IMMUNOMODULATORY PROPERTIES BY TREPROSTINIL
    Publication number: 20180110807
    Abstract: Provided are methods for treating or preventing vasculopathy comprising administering to a subject in need thereof , ac composition comprising a mesenchymal stem cell (MSC), or a part of a culture medium that has been in contact with the MSC and comprises one or more components of the MSC, or an exosome derived from the MSC. Pharmaceutical compositions suitable for such treatment is also provided.
    Type: Application
    Filed: October 23, 2017
    Publication date: April 26, 2018
    Applicant: United Therapeutics Corporation
    Inventors: Roger Marquez Ilagan, Sarah Hogan, John B. Cheadle
  • EXTRACELLULAR VESICLES WITH ENHANCED POTENCY
    Publication number: 20170360840
    Abstract: Provided are methods for isolating potent extracellular vesicle or exosome populations from mesenchymal stromal cells, and the use of the isolated extracellular vesicles or exosomes in treating vasculopathy, including pulmonary hypertension, bronchopulmonary dysplasia, and disease and conditions associated with mitochondrial dysfunction.
    Type: Application
    Filed: June 16, 2017
    Publication date: December 21, 2017
    Applicant: United Therapeutics Corporation
    Inventors: Sarah HOGAN, Roger Marquez ILAGAN, Maria Pia RODRIGUEZ, Carolina MEDRANO, John CHEADLE