Abstract: A composition comprising an aqueous dispersion of lipid vesicles encapsulating at least one compound which screens out UV radiation and contains at least one free or at least partially neutralized acidic function, wherein the lipid vesicles have a lipid membrane formed from at least one nonionic amphiphilic lipid (A) or from at least one saturated hydrocarbon ionic amphiphilic lipid (B) having an iodine number of less than 10, and from at least one totally neutralized ionic amphiphilic lipid (C) is disclosed. The use of this composition as a base for products to care for the skin, the scalp, the hair, the eyelashes or the eyebrows, as a base for make-up products, and more particularly as bases for compositions to protect the human epidermis, the hair, the eyelashes or the eyebrows against ultraviolet rays are also disclosed.