Patents by Inventor Roger Smith, III

Roger Smith, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of identification of animals resistant or susceptible to disease such as ruminant brucellosis, tuberculosis, paratuberculosis and salmonellosis
    Patent number: 6114118
    Abstract: The present invention relates to materials and methods for identifying animals that are resistant or susceptible to diseases associated with intracellular parasites such as brucellosis, tuberculosis, paratuberculosis and salmonellosis. More particularly, the present invention relates to the identification of a gene, called NRAMP1, which is associated with the susceptibility or resistance of an animal, such as an artiodactyla to diseases such as brucellosis, tuberculosis, paratuberculosis and salmonellosis. Still more particularly, the present invention relates to the identification of specific sequences of bovine NRAMP1 which associate with resistance or susceptibility to ruminant brucellosis, tuberculosis, paratuberculosis and salmonellosis, and to the method of identifying said sequences to identify animals who are susceptible or resistant to disease.
    Type: Grant
    Filed: July 30, 1997
    Date of Patent: September 5, 2000
    Assignees: Texas A&M University System, McGill University
    Inventors: Joe W. Templeton, Jianwei Feng, L. Garry Adams, Erwin Schurr, Philippe Gros, Donald S. Davis, Roger Smith, III
  • Vaccine comprising Brucella abortus which has O polysaccharide antigen absent
    Patent number: 5718903
    Abstract: The present invention is an improved vaccine against Brucella abortus which permits differentiation between vaccinated and field strain infected cattle. The vaccine can be administered in two different forms: (1) cell envelopes isolated from an O polysaccharide antigen deficient, stable transposon mutant of B. abortus or (2) an O polysaccharide antigen deficient, stable transposon mutant of B. abortus.
    Type: Grant
    Filed: February 14, 1994
    Date of Patent: February 17, 1998
    Assignee: The Texas A&M University System
    Inventors: Leslie Garry Adams, Richard P. Crawford, Donald S. Davis, Thomas A. Ficht, Roger Smith, III, Blair A. Sowa, Joe W. Templeton, John D. Williams, Albert M. Wu
  • Differential diagnostic assay for brucellosis
    Patent number: 5190860
    Abstract: An immunoassay procedure is provided which exhibits increased specificity over current procedures. The procedure allows the differentiation of animals infected with Brucella abortus from animals vaccinated with Brucella abortus Strain 19. The invention employs unique monospecific monoclonal antibodies having particular affinity, specificity and binding characteristics directed to a B. abortus lipopolysaccharide antigen. The invention also concerns continuous hybrid cell lines for producing the unique monoclonal antibodies.
    Type: Grant
    Filed: October 30, 1989
    Date of Patent: March 2, 1993
    Assignee: The Texas A & M University System
    Inventors: Leslie G. Adams, Roger Smith, III, Joe W. Templeton, Kathleen A. Overholt