Abstract: A laboratory instrument for processing at least one sample is disclosed. The laboratory instrument includes at least one housing having at least one sample processing device disposed therein, at least one reagent storage compartment reversibly removable from the housing, and at least one safety indicator. The safety indicator is configured for indicating if the reagent storage compartment has been removed from the housing and reinserted into the housing. The laboratory instrument is configured for automatically altering a detectable state of the safety indicator during the process of removing and reinserting the reagent storage compartment.

Abstract: A method for detection of a bottom of a well of a multiwell plate for a pipetting device is disclosed. The pipetting device includes a pipetting head configured for being coupled to a plurality of pipetting tips. A force sensor configured for measuring a resistance force depending on a force on a pipetting tip exerted by the bottom is used. The method includes measuring the resistance force during movement of one of the pipetting tips from a start position downstream towards the bottom of the well and stopping the movement at a bottom position. The method further includes storing the bottom position together with a corresponding logical position of the well in the multiwell plate in a database. Further disclosed is a pipetting device, a laboratory instrument for processing and/or analyzing a sample and a computer program and a computer-readable storage medium for performing the method.

Abstract: A laboratory instrument for processing at least one sample is disclosed. The laboratory instrument includes at least one housing having at least one sample processing device disposed therein, at least one reagent storage compartment reversibly removable from the housing, and at least one safety indicator. The safety indicator is configured for indicating if the reagent storage compartment has been removed from the housing and reinserted into the housing. The laboratory instrument is configured for automatically altering a detectable state of the safety indicator during the process of removing and reinserting the reagent storage compartment.