Abstract: Embodiments described here are directed to novel methods for detecting commensal bacteria-specific antibodies, such as commensal bacteria-specific immunoglobulin antibodies, in a blood sample or tissue fluid from a subject suspected of or suffering from a B cell malignancy, where the methods are for early detection or diagnosis of B cell malignancies and for early detection of relapse or recurrence of a B cell malignancy in remission patients previously diagnosed as suffering from a B cell malignancy. Also, described are embodiments directed to apparatuses for use with the novel methods described here. Methods of treating a subject suspected of or suffering from a B cell malignancy or a relapse or a recurrence of a B cell malignancy that can be used in combination with or without the methods of detecting commensal bacteria-specific antibodies and/or standard of care treatment are also provided here.

Abstract: This invention relates to a method of treating acute myelogenous leukemia with TPA along with Dexamethasone and choline magnesium trisalicylate.

Abstract: This invention relates to a method of treating acute myelogenous leukemia with TPA along with Dexamethasone and choline magnesium trisalicylate.

Abstract: This invention pertains to a method for treating a human with human immunodeficiency virus infection which comprises administering to the human a therapeutically effective amount of a thymidine analog, which analog acts as an inhibitor of viral reverse transcriptase necessary for viral replication of human immunodeficiency virus, and a thymidylate synthase inhibitor, or pharmaceutically acceptable salts thereof.

Abstract: This invention pertains to a method for treating a human with human immunodeficiency virus infection which comprises administering to the human a therapeutically effective amount of a thymidine analog, which analog acts as an inhibitor of viral reverse transcriptase necessary for viral replication of human immunodeficiency virus, and a thymidylate synthase inhibitor, or pharmaceutically acceptable salts thereof.

Abstract: The present invention pertains to a genetically altered human immunodeficiency virus type 1 (HIV-1) which replicates only in human CD4+ cells that express the Tax protein of Human T-cell Lymphotropic Virus Type I (HTLV-I), wherein the HIV long terminal repeat (LTR) promoter and enhancer sequences (NF-kappa-B and Sp1 binding sites) of the genetically altered human immunodeficiency virus type 1 have been replaced by two copies of the HTLV-I LTR 21 base pair repeat Tax-responsive element (TRE). The present invention also pertains to methods for killing HTLV-1 infected cells in humans with HTLV-1 disease (HTLV-1 tumors and HAM/TSP) with the novel genetically altered human immunodeficiency virus type 1 (HIV-1).