Abstract: A cutting guide having a seam allowance recess and methods of cutting a piece of material with such cutting guide.

Abstract: Titanium alloys formed into a part or component used in applications where a key design criterion is the energy absorbed during deformation of the part when exposed to impact, explosive blast, and/or other forms of shock loading is described. The titanium alloys generally comprise a titanium base with added amounts of aluminum, an isomorphous beta stabilizing element such as vanadium, a eutectoid beta stabilizing element such as silicon and iron, and incidental impurities. The titanium alloys exhibit up to 70% or more improvement in ductility and up to a 16% improvement in ballistic impact resistance over a Ti-6Al-4V alloy, as well as absorbing up to 50% more energy than the Ti-6Al-4V alloy in Charpy impact tests. A method of forming a part that incorporates the titanium alloys and uses a combination of recycled materials and new materials is also described.

Abstract: The present invention relates to topical pharmaceutical emulsion compositions comprising a therapeutically effective amount of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a pharmaceutically acceptable salt thereof, an oil phase, a water phase, a surfactant, and an antioxidant, and wherein the emulsion composition is homogeneous and/or the active is solubilized in the oil phase. The invention also relates to methods of treating a dermatological condition or disorder in a patient by administering the present compositions to the skin of the patient.

Abstract: The invention relates to antibody molecules having specificity for antigenic determinants of human IL-13, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.

Abstract: A cutting guide having a seam allowance recess and methods of cutting a piece of material with such cutting guide.

Abstract: The invention relates to antibody molecules having specificity for antigenic determinants of human IL-13, therapeutic uses of the antibody molecules and methods for producing antibody molecules.

Abstract: The invention relates to a contouring device for a seat base, backrest, or mattress. The device comprises a substrate having a first surface and an opposing second surface, the first and second surfaces each comprising a plurality of pockets adapted to receive one or more inserts therein. Inserts of various sizes and shapes can be placed within selected pockets of the device to provide a contoured surface that suits the needs of the user of the device. For example, the device can be adapted to provide contours that encourage a user to adopt a preferred posture when seated or lying down.

Abstract: An alpha-beta titanium alloy comprises Al at a concentration of from about 4.7 wt. % to about 6.0 wt. %; V at a concentration of from about 6.5 wt. % to about 8.0 wt. %; Si at a concentration of from about 0.15 wt. % to about 0.6 wt. %; Fe at a concentration of up to about 0.3 wt. %; O at a concentration of from about 0.15 wt. % to about 0.23 wt. %; and Ti and incidental impurities as a balance. The alpha-beta titanium alloy has an Al/V ratio of from about 0.65 to about 0.8, where the Al/V ratio is defined as the ratio of the concentration of Al to the concentration of V in the alloy, with each concentration being in weight percent (wt %).

Abstract: A cutting guide having a seam allowance recess and methods of cutting a piece of material with such cutting guide.

Abstract: One embodiment is directed to a system for controllably managing unproductive cough in a patient having a tissue structure that has been genetically modified to have light sensitive protein, comprising: a light delivery element configured to direct radiation to at least a portion of a targeted tissue structure; a light source configured to provide light to the light delivery element; and a controller operatively coupled to light source; wherein the controller is configured to be operated by an operator to illuminate the targeted tissue structure with radiation such that a membrane potential of cells comprising the targeted tissue structure is modulated at least in part due to exposure of the light sensitive protein to the radiation.

Abstract: One embodiment is directed to a method for controllably managing unproductive cough in a patient having a tissue structure that has been genetically modified to have light sensitive protein, comprising: providing a light delivery element configured to direct radiation to at least a portion of a targeted tissue structure, a light source configured to provide light to the light delivery element, and a controller operatively coupled to light source; and operating the controller to illuminate the targeted tissue structure with radiation such that a membrane potential of cells comprising the targeted tissue structure is modulated at least in part due to exposure of the light sensitive protein to the radiation.

Abstract: One embodiment is directed to a method for managing unproductive cough in a patient, comprising: providing an applicator comprising a resistive heating element and being configured to be positioned adjacent a portion of a targeted nerve tissue for treatment; providing a power source configured to provide electrical current to the resistive heating element; providing a current controller operatively coupled to the power source and configured to raise the temperature of the portion of the targeted nerve tissue to inhibit nerve conduction; and modulating the temperature of the portion of the targeted nerve tissue to inhibit nerve conduction.

Abstract: One embodiment is directed to a system for managing unproductive cough in a patient, comprising: an applicator comprising a resistive heating element and being configured to be positioned adjacent a portion of a targeted nerve tissue for treatment; a power source configured to provide electrical current to the resistive heating element; and a current controller operatively coupled to the power source and configured to raise the temperature of the portion of the targeted nerve tissue to inhibit nerve conduction.

Abstract: A cutting guide having a seam allowance recess and methods of cutting a piece of material with such cutting guide.

Abstract: Certain aspects of the present disclosure generally relate to voltage-controlled oscillators (VCOs) using a lowered or an adjustable negative transconductance (?gm) compared to conventional VCOs. This ?gm degeneration technique suppresses the noise injected into an inductor-capacitor (LC) tank of the VCO, thereby providing lower signal-to-noise ratio (SNR) for a given VCO voltage swing, lower power consumption, and decreased phase noise. One example VCO generally includes a resonant tank circuit, an active negative transconductance circuit connected with the resonant tank circuit, and a bias current circuit for sourcing or sinking a bias current through the resonant tank circuit and the active negative transconductance circuit to generate an oscillating signal. The active negative transconductance circuit includes cross-coupled transistors and an impedance connected between the cross-coupled transistors and a reference voltage.

Abstract: This invention is a novel air supply register that modulates the incoming air supply from the under floor air duct. This air register is able to monitor the air temperature leaving the server stack thereby improving the response time of the HVAC system. Since the register has adjustable louvers that can modulate the inlet air flow into the server stack; it will save energy by reducing the supply air to the server stack when the cool incoming air is not needed. This reduces hot spots in the data center because the cool incoming air can be directed to server racks that need cooling. This self-modulation of the air register is not available in conventional floor registers.

Abstract: One embodiment is directed to a system for treating hypertension within the eye of a patient, comprising a light delivery element optically intercoupled between a light source and a targeted tissue structure of the eye; wherein the targeted tissue structure has been genetically modified to have light sensitive protein; and wherein exposure of the genetically modified targeted tissue structure to radiation delivered through the light delivery element modulates the contractility of the genetically modified targeted tissue structure to reduce an intraocular pressure within the eye.

Abstract: One embodiment is directed to a method for treating hypertension within the eye of a patient, comprising: delivering an effective amount of polynucleotide comprising an exogenous receptor genetic material which is expressed in a targeted tissue structure of the eye, wherein the targeted tissue structure has been genetically modified to have light sensitive protein; waiting for a period of time to ensure that sufficient portions of the targeted tissue structure of the eye will express the desired light sensitive protein; and causing controlled mechanical changes to the permeability of the eye by directing light to the targeted tissue structure through a light deliver element optically intercoupled between a light source and the targeted tissue structure of the eye.

Abstract: An ultrasonic detector suitable for mounting in a position for surveying an area for a source of airborne ultrasound, which detector comprises a sensor for detecting an ultrasonic sound signal, characterised by a transducer configured to produce a broadband ultrasonic sound signal for reception by said sensor enabling said ultrasonic detector to perform a self-test.