Abstract: A breath-actuated jet nebulizer is provided, having a body enclosing a gas jet that creates a Venturi effect. The Venturi requires a baffle in close proximity to the gas jet. The baffle is movable in response to the inhalation of the patient, such that the baffle has a default (resting) position distal to the gas jet such that no Venturi effect is created, and no nebulization occurs. During the inhalation phase of a breathing cycle, a diaphragm flexes and pushes the baffle into close proximity with the Venturi gas jet, such that a Venturi effect is created that causes a low pressure zone in proximity to one or more liquid orifices that draw a drug solution into the Venturi, where the solution is nebulized. Also disclosed is an exhalation filter to prevent infectious particles from the patient from escaping and endangering nearby caregivers.

Abstract: A breath-enhanced jet nebulizer is configured with a low liquid retention reservoir and a narrow liquid delivery passage to efficiently and efficiently aerosolize small drug volumes with minimal waste. Aerosol particles are directed through aerosol passage for delivery, although larger liquid particles are directed away from the aerosol outlet and recycled to the liquid reservoir.

Abstract: A breath actuated nebulizer for administration of an inhaled medication to a patient is provided with a generally cylindrical body in a horizontal orientation to the patient. Within the body is a Venturi configured to nebulizer a liquid medication in a reservoir. Within the body is a shaft integrated with a baffle and diaphragm that slides horizontally in response to the breathing of a patient. During inhalation by the patient, the diaphragm flexes shifting the baffle over the Venturi, allowing nebulization to occur. When the patient exhales, the diaphragm flexes to a default position in which the baffle is distal to the Venturi, thereby stopping the nebulization. The diaphragm is biased to rest in this default position until the patient inhales again.

Abstract: A breath actuated nebulizer for administration of an inhaled medication to a patient is provided with a generally cylindrical body in a horizontal orientation to the patient. Within the body is a Venturi configured to nebulizer a liquid medication in a reservoir. Within the body is a shaft integrated with a baffle and diaphragm that slides horizontally in response to the breathing of a patient. During inhalation by the patient, the diaphragm flexes shifting the baffle over the Venturi, allowing nebulization to occur. When the patient exhales, the diaphragm flexes to a default position in which the baffle is distal to the Venturi, thereby stopping the nebulization. The diaphragm is biased to rest in this default position until the patient inhales again.

Abstract: A breath actuated nebulizer for administration of an inhaled medication to a patient is provided with a generally cylindrical body in a horizontal orientation to the patient. Within the body is a Venturi configured to nebulize a liquid medication in a reservoir. Within the body is a shaft integrated with a baffle and diaphragm that slides horizontally in response to the breathing of a patient. During inhalation by the patient, the diaphragm flexes shifting the baffle over the Venturi, allowing nebulization to occur. When the patient exhales, the diaphragm flexes to a default position in which the baffle is distal to the Venturi, thereby stopping the nebulization. The diaphragm is biased to rest in this default position until the patient inhales again.

Abstract: A breath-enhanced jet nebulizer is configured with a low liquid retention reservoir and a narrow liquid delivery passage to efficiently and efficiently aerosolize small drug volumes with minimal waste. Aerosol particles are directed through aerosol passage for delivery, although larger liquid particles are directed away from the aerosol outlet and recycled to the liquid reservoir.

Abstract: The present disclosure relates to the treatment of tuberculosis and/or multi-drug resistant tuberculosis by inhalable pharmaceutical compositions that include an interferon and at least one therapeutic agent selected from the group of fluoroquinolone, aminoglycoside and nitroimidazole. The present disclosure also relates to an inhalable pharmaceutical composition that includes an interferon and at least one therapeutic agent selected from the group of fluoroquinolone, aminoglycoside and nitroimidazole.

Abstract: A breath actuated nebulizer for administration of an inhaled medication to a patient is provided with a generally cylindrical body in a horizontal orientation to the patient. Within the body is a Venturi configured to nebulize a liquid medication in a reservoir. Within the body is a shaft integrated with a baffle and diaphragm that slides horizontally in response to the breathing of a patient. During inhalation by the patient, the diaphragm flexes shifting the baffle over the Venturi, allowing nebulization to occur. When the patient exhales, the diaphragm flexes to a default position in which the baffle is distal to the Venturi, thereby stopping the nebulization. The diaphragm is biased to rest in this default position until the patient inhales again.

Abstract: This invention discloses a chamber adapted for the administration of medication from a source of aerosolized drug, such as a metered dose inhaler (MDI) or nebulizer, comprising a conduit with an oval cross section, a mounting for the MDI at the rear, an annular one-way valve at the front in fluid communication with the inhalation airway of the patient that permits air to flow out of the chamber during an inhalation by the patient, but prevents exhaled air from entering the chamber, an exhaust valve in the front section that provides an effective seal during inhalation, and a solid state whistle, wherein the whistle is adapted to making a sound if the air pressure within the chamber is below a predefined threshold. The inventive chamber may be used to directly administer inhaled medication to the mouth of a patient, or it may be used with an inhalation mask.