Patents by Inventor Rohit Nandkumar KARNIK

Rohit Nandkumar KARNIK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11612839
    Abstract: Systems, devices, and methods for detecting contamination (e.g., bacteria) in fluid are provided. The systems, devices, and methods allow for filtering a fluid sample using a filter to capture and concentrate cells (e.g., bacteria) to detect electrochemical properties thereof. The cells can be exposed to a reagent that diffuses into the cells to produce a product of interest that can be used in analysis of the fluid sample. The product of interest can diffuse out of the filter into a fluid storage component for detection and analysis by an analysis component. After the sampling is completed, the filter can be detached and discarded. Other aspects of the present disclosure, including enhancements and various systems and methods for concentrating cells and analyzing the same, are also provided.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: March 28, 2023
    Assignee: Massachusetts Institute of Technology
    Inventors: Michael S. Bono, Sydney B. Beasley, Emily Barret Hanhauser, Chintan Vaishnav, Anastasios John Hart, Rohit Nandkumar Karnik
  • Patent number: 11428618
    Abstract: Systems and methods for monitoring air particulate matter are provided herein that capture particles from the air for analysis. Particles are captured using electrostatic and/or mechanical means to deflect particles toward a substrate. Electrostatic precipitation causes charged carriers to deflect towards a charged substrate. Filtration-based means employ filters and/or fibers to capture particles from air flowing therethrough. A sensor such as a camera is used to read the captured particles. An illumination source directs light towards the substrate, causing the particles to scatter light, which the sensor can detect and derive information or imaging therefrom, which can also be used for further particle or pollution analyses. The substrate can be replenished using electrostatic techniques such as reverse electrostatic force, or mechanical means such as cleaning using a brush or replacing a tape substrate.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: August 30, 2022
    Assignee: Massachusetts Institute of Technology
    Inventors: Rohit Nandkumar Karnik, An Chang
  • Publication number: 20200047093
    Abstract: Systems, devices, and methods for detecting contamination (e.g., bacteria) in fluid are provided. The systems, devices, and methods allow for filtering a fluid sample using a filter to capture and concentrate cells (e.g., bacteria) to detect electrochemical properties thereof. The cells can be exposed to a reagent that diffuses into the cells to produce a product of interest that can be used in analysis of the fluid sample. The product of interest can diffuse out of the filter into a fluid storage component for detection and analysis by an analysis component. After the sampling is completed, the filter can be detached and discarded. Other aspects of the present disclosure, including enhancements and various systems and methods for concentrating cells and analyzing the same, are also provided.
    Type: Application
    Filed: October 18, 2017
    Publication date: February 13, 2020
    Inventors: Michael S. Bono, Sydney B. Beasley, Emily Barret Hanhauser, Chintan Vaishnav, Anastasios John Hart, Rohit Nandkumar Karnik
  • Publication number: 20190346356
    Abstract: Systems and methods for monitoring air particulate matter are provided herein that capture particles from the air for analysis. Particles are captured using electrostatic and/or mechanical means to deflect particles toward a substrate. Electrostatic precipitation causes charged carriers to deflect towards a charged substrate. Filtration-based means employ filters and/or fibers to capture particles from air flowing therethrough. A sensor such as a camera is used to read the captured particles. An illumination source directs light towards the substrate, causing the particles to scatter light, which the sensor can detect and derive information or imaging therefrom, which can also be used for further particle or pollution analyses. The substrate can be replenished using electrostatic techniques such as reverse electrostatic force, or mechanical means such as cleaning using a brush or replacing a tape substrate.
    Type: Application
    Filed: December 19, 2017
    Publication date: November 14, 2019
    Inventors: Rohit Nandkumar Karnik, An Chang
  • Patent number: 10011817
    Abstract: The present invention provides systems for cell separation based on cell rolling on surfaces along edges of regions coated with cell adhesion molecules. A variety of designs of coated regions and edges are disclosed.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: July 3, 2018
    Assignee: Massachusetts Institute of Technology
    Inventors: Rohit Nandkumar Karnik, Seungpyo Hong, Ying Mei, Daniel Griffith Anderson, Jeffrey Michael Karp, Robert S. Langer, Suman Bose
  • Publication number: 20170204367
    Abstract: The present invention provides systems for cell separation based on cell rolling on surfaces along edges of regions coated with cell adhesion molecules. A variety of designs of coated regions and edges are disclosed.
    Type: Application
    Filed: December 29, 2016
    Publication date: July 20, 2017
    Inventors: Rohit Nandkumar Karnik, Seungpyo Hong, Ying Mei, Daniel Griffith Anderson, Jeffrey Michael Karp, Robert S. Langer, Suman Bose
  • Patent number: 9555413
    Abstract: The present invention provides systems for cell separation based on cell rolling on surfaces along edges of regions coated with cell adhesion molecules. A variety of designs of coated regions and edges are disclosed.
    Type: Grant
    Filed: March 24, 2015
    Date of Patent: January 31, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: Rohit Nandkumar Karnik, Seungpyo Hong, Ying Mei, Daniel Griffith Anderson, Jeffrey Michael Karp, Robert S. Langer, Suman Bose
  • Publication number: 20150246354
    Abstract: The present invention provides systems for cell separation based on cell rolling on surfaces along edges of regions coated with cell adhesion molecules. A variety of designs of coated regions and edges are disclosed.
    Type: Application
    Filed: March 24, 2015
    Publication date: September 3, 2015
    Inventors: Rohit Nandkumar Karnik, Seungpyo Hong, Ying Mei, Daniel Griffith Anderson, Jeffrey Michael Karp, Robert S. Langer, Suman Bose
  • Publication number: 20150174549
    Abstract: A simple and versatile coaxial turbulent jet mixer can synthesize a range of nanoparticles at high throughput, while maintaining the advantages of homogeneity, reproducibility, and tunability that are normally accessible only in specialized microscale mixing devices. Rapid mixing down to a timescale of 7 ms can be achieved by controlling the Reynolds number, providing homogeneous and controllable environments for formation of nanoparticles, for example, by precipitation. The device fabrication does not require specialized machining, making it accessible for a wide range of biomedical laboratories.
    Type: Application
    Filed: October 25, 2014
    Publication date: June 25, 2015
    Applicants: THE BRIGHAM AND WOMEN'S HOSPITAL CORPORATION, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Jong-Min Lim, Laura Marie Gilson, Sunandini Chopra, Omid Cameron Farokhzad, Rohit Nandkumar Karnik, Archana Swami
  • Patent number: 8986988
    Abstract: The present invention provides systems for cell separation based on cell rolling on surfaces along edges of regions coated with cell adhesion molecules. A variety of designs of coated regions and edges are disclosed.
    Type: Grant
    Filed: September 29, 2008
    Date of Patent: March 24, 2015
    Assignee: Massachusetts Institute of Technology
    Inventors: Rohit Nandkumar Karnik, Seungpyo Hong, Ying Mei, Daniel Griffith Anderson, Jeffrey Michael Karp, Robert S. Langer, Suman Bose
  • Publication number: 20100304485
    Abstract: The present invention provides systems for cell separation based on cell rolling on surfaces along edges of regions coated with cell adhesion molecules. A variety of designs of coated regions and edges are disclosed.
    Type: Application
    Filed: September 29, 2008
    Publication date: December 2, 2010
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Rohit Nandkumar KARNIK, Seungpyo HONG, Ying MEI, Daniel Griffith ANDERSON, Jeffrey Michael KARP, Robert S. LANGER, Suman BOSE