Abstract: The invention relates to novel bispecific antigen binding molecules, comprising at least two antigen binding domains capable of specific binding to OX40 and a particular antigen binding domain capable of specific binding to Fibroblast Activation Protein (FAP), and to methods of producing these molecules and to methods of using the same.

Abstract: Filling line for heat-treating and filling a liquid into containers (e.g., bottles), comprising a pre-heater for pre-heating the liquid, a heater for heating the liquid after pre-heating, a cooler for cooling down the liquid after heating, and a filling unit for filling the liquid into the containers, where the filling line is suitable for hot filling and cold filling, where the liquid path from the pre-heater to the filling unit for hot filling differs from the liquid path from the pre-heater to the filling unit for cold filling, and the filling line comprises a switching option for switching between the two liquid paths; and a method for heat-treating and filling containers with a liquid in which such a filling line is used.

Abstract: Filling line for heat-treating and filling a liquid, comprising a pre-heater (1) for pre-heating the liquid, a heater (2) for heating the liquid after pre-heating, a cooler (3) for cooling down the liquid after heating, an a filling unit (4) for filling the liquid, where the filling line is suitable for hot filling and cold filling, where the liquid path from the pre-heater to the filling unit for hot filling differs from the liquid path from the pre-heater to the filling unit for cold filling, and the filling line comprises a switching option (5) for switching between the two liquid paths; and a method for heat-treating and filling a liquid in which such a filling line is used.