Abstract: The present invention provides a compound capable of binding to the ubiquinone binding site of DHODH which contains a non-aromatic ring system as a core structure, a group capable of interacting with structural elements of subsite 2 or 3 of the ubiquinone binding site of DHODH and a group capable of interacting hydrophobically with structural elements of subsite 1 of the ubiquinone binding site of DHODH. Furthermore, the present invention provides a compound capable of binding to the ubiquinone binding site of DHODH which contains an aromatic ring system as a core structure, a group capable of interacting with residues His 56 and/or Tyr 356 of subsite 3 of the ubiquinone binding site of DHODH and a group capable of interacting hydrophobically with structural elements of subsite 1 of the ubiquinone binding site of DHODH.

Abstract: The present invention provides a compound capable of binding to the ubiquinone binding site of DHODH which contains a non-aromatic ring system as a core structure, a group capable of interacting with structural elements of subsite 2 or 3 of the ubiquinone binding site of DHODH and a group capable of interacting hydrophobically with structural elements of subsite 1 of the ubiquinone binding site of DHODH. Furthermore, the present invention provides a compound capable of binding to the ubiquinone binding site of DHODH which contains an aromatic ring system as a core structure, a group capable of interacting with residues His 56 and/or Tyr 356 of subsite 3 of the ubiquinone binding site of DHODH and a group capable of interacting hydrophobically with structural elements of subsite 1 of the ubiquinone binding site of DHODH.

Abstract: A controllable drive (1) suitable for a motor vehicle coolant pump (2) comprises a rotatably mounted shaft (5), a driven member (7) which is rotationally fixedly mounted on the shaft (5), a driving member (9) which is mounted so as to be rotatable relative to the shaft (5), and a coupling region (7/8) which is arranged between the driving and driven members (9, 7) and holds a viscous fluid. At least one first flow path and at least one second flow path connect a fluid reservoir to the coupling region (7/8), and an actuation device (11a, 11b, 12, 13, 14) changes at least one passage opening of at least one flow path. A coupling housing (8, 8a, 8b) is connected to the driving member (9), and the actuator (14) is arranged within the coupling housing (8, 8a, 8b).

Abstract: A connector includes a plug connector and a mating connector. The plug connector includes a housing with an open front end, an insulated inner conductor disposed within the housing, a clamping sleeve, and an axially movable sliding sleeve disposed radially outside the clamping sleeve. The sliding sleeve can be positioned in a working position where it surrounds the clamping sleeve and exerts a radially inward-directed force. The mating connector, which is receivable within the housing, includes a clamping surface. A force Fr introduced radially from the sliding sleeve toward the clamping sleeve when the sliding sleeve is in the working position, is redirected by the clamping sleeve into an axial force component Fa which is introduced from the clamping sleeve toward the clamping surface.

Abstract: The invention concerns a coaxial connector plug and mating plug in which the connector plug has a connector housing that is open at the front end for plugging in the mating plug and contains a canal holding an insulated internal conductor contact, with a clamp sleeve and a sliding sleeve that can be moved axially to mechanically connect the connector housing with the mating plug, wherein the sliding sleeve surrounds the clamp sleeve in the operating position and exerts on it a force directed radially inward in the operating position, and wherein the clamp sleeve can be made to rest against the mating plug at a clamp surface, and wherein an outer conductor contact surface of the mating plug can be clamped axially against an outer conductor contact surface of the connector plug.

Abstract: A connector includes a plug connector and a mating connector. The plug connector includes a housing with an open front end, an insulated inner conductor disposed within the housing, a clamping sleeve and an axially movable sliding sleeve disposed radially outside the clamping sleeve. The sliding sleeve can be positioned in a working position where it surrounds the clamping sleeve and exerts a radially inward-directed force. The mating connector, which is receivable within the housing, includes a clamping surface. A force Fr introduced radially from the sliding sleeve toward the clamping sleeve when the sliding sleeve is in the working position is redirected by the clamping sleeve into an axial force component Fa which is introduced from the clamping sleeve toward the clamping surface.

Abstract: A regulatable drive for a motor vehicle, in particular for a water pump in a motor vehicle, has a rotatably mounted shaft, on which is located a rotatably mounted drive member and a rotationally fixed driven member. Between the drive member and driven member, a coupling region is defined, which can receive a viscous fluid for selectively coupling the drive member and driven member. The regulatable drive includes at least one first and at least one second flow path, which connect a fluid storage space to the coupling region, and it has a device which can be varied in its position by means of at least one actuator and which varies at least one passage orifice of at least one of the flow paths.

Abstract: An electrical plug connector has a flat insertion pin and a flat insertion sheath into which the flat insertion pin can be inserted. The flat insertion pin, in its end region pointing in the insertion direction, has a widened portion embodied in the shape of a hammerhead.

Abstract: The electrical plug connector has a flat insertion pin (10) and a flat insertion sheath (12) into which the flat insertion pin (10) can be inserted. The flat insertion pin (10), in its end region pointing in the insertion direction (20), has a widened portion (22). The end region of the flat insertion pin (10) having the widened portion (22) is embodied in the shape of a hammerhead.