Abstract: A method for treating hard tissue infection in a site-specific manner, comprising preparing a negative mold of the hard tissue using an impression material which contains a diagnostic additive which generates an identifiable signal on contact with infected tissue; applying a treatment agent to the negative mold at one or more of infected sites; and re-applying the negative mold on the originally molded hard tissue for a suitable period of time. Also disclosed are methods for making the negative mold, a mouthpiece corresponding to the negative mold, and a treatment device, as well as the treatment device and mouse piece so produced.

Abstract: The invention relates to a device for storing and dispensing a flowable composition. Said device comprises a first (1) and a second film (2), a dispensing zone (4), a first chamber (5), containing a first substance (A) and a second chamber (6), containing a second substance (B). Said chambers are interconnected by a transition zone (3) that can be selectively opened. At least one of the films is deep-drawn in the region of the chambers and at least one of the films is pre-formed in the region of the second chamber, in such a way that once the device has been activated by opening the transition zone, the first substance can to a great extent be completely transferred to a second chamber, increasing the volume of said chamber as a result.

Abstract: The invention relates to a device for storing and dispensing a flowable composition. Said device comprises a first (1) and a second film (2), a dispensing zone (4), a first chamber 5), containing a first substance (A) and a second chamber (6), containing a second substance (B). Said chambers are interconnected by a transition zone (3) that can be selectively opened. At least one of the films is deep-drawn in the region of the chambers and at least one of the films is pre-formed in the region of the second chamber, in such a way that once the device has been activated by opening the transition zone, the first substance can to a great extent by completely transferred to the second chamber, increasing the volume of said chamber as a result.

Abstract: A method for treating hard tissue infection in a site-specific manner, comprising preparing a negative mold of the hard tissue using an impression material which contains a diagnostic additive which generates an identifiable signal on contact with infected tissue; applying a treatment agent to the negative mold at one or more of infected sites; and re-applying the negative mold on the originally molded hard tissue for a suitable period of time. Also disclosed are methods for making the negative mold, a mouthpiece corresponding to the negative mold, and a treatment device, as well as the treatment device and mouse piece so produced.