Abstract: The present invention relates to methods and compositions for increasing insulin sensitivity comprising the administration of anti-oxidized LDL antibodies.

Abstract: Methods and devices for coding a slot in a cellular radio system are described. The coding allows for increased robustness and can be designed to be backwards compatible with transmission for e.g. GSM, GPRS, EGPRS and EGPRS2.

Abstract: The invention provides binding molecules, including antibody molecules which selectively bind to a cell surface antigen of a target cell, and wherein the binding molecules, on binding the cell surface antigen, induce apoptosis of the target cell. There is also provided methods of and pharmaceutical compositions for apoptosis induction and uses thereof.

Abstract: An intermediary node is adapted for receiving a sequence of packets from a server, wherein the intermediary node comprises a time estimator adapted for performing the following steps—resolving the sequence number (k) and time of arrival to the intermediary node for at least a plurality (q) of incoming packets; establishing the frame period of the incoming packets (T); establishing a sequence of normalized packet arrival times (ek) as corresponding to the established frame period (T); calculating the relative arrival time (rtrec, k) of the plurality (q) of incoming packets in relation to the normalized packet arrival times; creating a cumulative density function (CDF) for a given sequence of packets; and establishing the threshold value for the relative arrival time (rtPL) yielding the predefined packet loss (PL) based on the cumulative density function (CDF).

Abstract: The invention provides a method for generating a polynucleotide sequence or population of sequences from parent single stranded polynucleotide sequences encoding one or more protein motifs, comprising the steps of a) providing single stranded DNA constituting plus and minus strands of parent polynucleotide sequences; b) digesting the single stranded polynucleotide sequences with a nuclease other than DNase I to generate populations of single stranded fragments; c) contacting the fragments generated from the plus strands with fragments generated from the minus strands and optionally, adding primer sequences that anneal to the 3? and 5? ends of at least one of the parent polynucleotides under annealing conditions; and d) amplifying the fragments that anneal to each other to generate at least one polynucleotide sequence encoding one or more protein motifs having altered characteristics as compared to the one or more protein motifs encoded by the parent polynucleotides.

Abstract: The invention relates to a scheduler for a TCP/IP based data communication system and a method for the scheduler. The communication system comprises a TCP/IP transmitter and a receiving unit (UE). The scheduler is associated with a Node comprising a rate measuring device for measuring a TCP/IP data rate from the TCP/IP transmitter and a queue buffer device for buffering data segments from the TCP/IP transmitter. The scheduler is arranged to receive information from the rate measuring device regarding the TCP/IP data rate and is arranged to adapt the permitted queue latency to a minimum value when the TCP/IP transmitter is in a slow start mode and to increase the permitted queue latency when the TCP/IP rate has reached a threshold value.

Abstract: Transmission unit comprising a first unit (CM_SCHDR) receiving scheduled first data (DATA2, DATA3) for transmission on at least a first channel, a power control unit (PWR_CTRL) for the first channel responsive to a respective closed loop power regulation signal (TCP_CMD), under which at least the transmit power rate of change is limited to a predetermined value per time unit, a packet data scheduler (HS_SCHDR) scheduling second data packets (DATA1), such as HSDPA data. A permitted power (P_PERM(t)) is defined as the maximum value of either the actual power of a previous instance (P_HS(t?1)) added with the predetermined value (d) or the determined possible power (P_POS(t)). Moreover, an available power is resolved. According to one aspect, the scheduling is performed within these limits. According to a further aspect the power level of the signaling and control channel (HS-SCCH) is further regulated during a transmission interval taking account of shared packet data channel (HS-PDSCH) power level.

Abstract: A transmitting unit comprising a first unit (CM_SCHDR) receiving scheduled first data (DATA2, DATA3) for transmission on at least a first channel, a power control unit (PWR_CTRL) for the first channel responsive to a respective closed loop power regulation signal (TCP_CMD), under which at least the transmit power rate of change is limited to a predetermined value per time unit, a packet data scheduler (HS_SCHDR) scheduling second data packets (DATA1), such as HSPDA data, for transmission on at least a second channel at an actual power level (P_H(t)), and a power amplifier (POWER_AMP) amplifying and outputting the scheduled first and second data, whereby the outputted first and second channels are subject to interference from one another, is shown.

Abstract: The invention provides a method for generating a polynucleotide sequence or population of sequences from parent single stranded polynucleotide sequences encoding one or more protein motifs, comprising the steps of a) providing single stranded DNA constituting plus and minus strands of parent polynucleotide sequences; b) digesting the single stranded polynucleotide sequences with a nuclease other than DNase I to generate populations of single stranded fragments; c) contacting said fragments generated from the plus strands with fragments generated from the minus strands and optionally, adding primer sequences that anneal to the 3? and 5? ends of at least one of the parent polynucleotides under annealing conditions; d) amplifying the fragments that anneal to each other to generate at least one polynucleotide sequence encoding one or more protein motifs having altered characteristics as compared to the one or more protein motifs encoded by said parent polynucleotides.

Abstract: The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.

Abstract: The use of immunotherapy against oxidised LDL to induce regression of pre-existing atherosclerotic lesions in an individual. The immunotherapy can be passive immunotherapy utilising antibodies that bind to epitopes present on oxidised LDL, or active immunotherapy utilising a vaccine composition for induction of an immune response against epitopes present on oxidised LDL.

Abstract: A single isolated antibody or antibody fragment thereof binds to multiple variant sequences within an epitope of HIV-1 Tat protein displayed in multiple strains and subtypes of HIV-1. This “pan-epitope” antibody is useful in therapeutic and prophylactic compositions and treatments of HIV-1 infection, regardless of strain. This pan-epitope antibody is useful in assays for the detection of levels of HIV-1 based on a measurement of the amount of Tat protein in a biological sample.

Abstract: The invention provides a method for generating a polynucleotide sequence or population of sequences from parent single stranded polynucleotide sequences encoding one or more protein motifs, comprising the steps of a) providing single stranded DNA constituting plus and minus strands of parent polynucleotide sequences; b) digesting the single stranded polynucleotide sequences with a nuclease other than DNase I to generate populations of single stranded fragments; c) contacting said fragments generated from the plus strands with fragments generated from the minus strands and optionally, adding primer sequences that anneal to the 3? and 5? ends of at least one of the parent polynucleotides under annealing conditions; d) amplifying the fragments that anneal to each other to generate at least one polynucleotide sequence encoding one or more protein motifs having altered characteristics as compared to the one or more protein motifs encoded by said parent polynucleotides.

Abstract: The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.

Abstract: An arrangement and a method for minimizing intracell and/or intercell interference for a data transmission system comprises a scheduler (2). A first base station (BS) receives information from user equipments (UE1-UE4) in a first cell (1) by means of a first antenna system (Rx, Tx). The scheduler (2) identifies the position of each user and allots a first time slot (TS1) to at least one user equipment (UE1) in a first cell segment (CS1) in the first cell (1). The scheduler (2) also allots the first time slot to at least one user (UE3) equipment in a second cell segment (CS2) in the first cell (1). The antenna system (Rx, Tx) then sends information from the base station (BS) simultaneously to all user equipments (UE1, UE3) allotted to the first time slot.

Abstract: The present invention relates to a method and arrangement for downlink power adjustment in a base station (210, 310, 610) comprising at least two similar hardware units: a first unit (231, 316a, 616a) and a second unit (232, 316b, 616b), in a communications network when moving a resource from said first unit to said second unit. The method comprises configuring said resource, providing a sample of a power level, transferring said power sample from said first unit to said second unit, and controlling the power level on the second unit towards a power value provided as a power level with turned off output power on said second unit.

Abstract: The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.

Abstract: The invention provides binding molecules, including antibody molecules which selectively bind to a cell surface antigen of a target cell, and wherein the binding molecules, on binding the cell surface antigen, induce apoptosis of the target cell. There is also provided methods of and pharmaceutical compositions for apoptosis induction and uses thereof.

Abstract: The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.

Abstract: The invention provides a method for generating a polynucleotide sequence or population of sequences from parent single stranded polynucleotide sequences encoding one or more protein motifs, comprising the steps of a) providing single stranded DNA constituting plus and minus strands of parent polynucleotide sequences; b) digesting the single stranded polynucleotide sequences with a nuclease other than DNase I to generate populations of single stranded fragments; c) contacting said fragments generated from the plus strands with fragments generated from the minus strands and optionally, adding primer sequences that anneal to the 3? and 5? ends of at least one of the parent polynucleotides under annealing conditions; d) amplifying the fragments that anneal to each other to generate at least one polynucleotide sequence encoding one or more protein motifs having altered characteristics as compared to the one or more protein motifs encoded by said parent polynucleotides.