Patents by Inventor Roland Gendron

Roland Gendron has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quinolinone compounds as 5-HTreceptor agonists
    Patent number: 7446114
    Abstract: The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Grant
    Filed: March 1, 2006
    Date of Patent: November 4, 2008
    Assignee: Theravance, Inc.
    Inventors: Adam A. Goldblum, Seok-ki Choi, Paul R. Fatheree, Roland Gendron, Lan Jiang, Daniel D. Long, Daniel Marquess, S. Derek Turner
  • Dual-acting antihypertensive agents
    Publication number: 20080269305
    Abstract: The invention is directed to compounds having the formula: wherein: Ar, r, Y, Z, Q, W, X, and R5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
    Type: Application
    Filed: April 23, 2008
    Publication date: October 30, 2008
    Inventors: Paul Allegretti, Seok-Ki Choi, Roland Gendron, Paul R. Fatheree, Keith Jendza, Robert Murray McKinnell, Darren McMurtrie, Brooke Olson
  • Indazole-carboxamide compounds
    Patent number: 7419989
    Abstract: The invention provides novel indazole-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: September 2, 2008
    Assignee: Theravance, Inc.
    Inventors: Paul Fatheree, Roland Gendron, Adam A Goldblum, Daniel D Long, Daniel Marquess, S. Derek Turner, Seok-Ki Choi
  • Quinolinone-carboxamide compounds
    Publication number: 20080167295
    Abstract: The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: March 13, 2008
    Publication date: July 10, 2008
    Inventors: Seok-Ki Choi, Paul Fatheree, Roland Gendron, Adam A. Goldblum, Lan Jiang, Daniel D. Long, Daniel Marquess
  • Quinolinone-carboxamide compounds
    Patent number: 7396933
    Abstract: The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Grant
    Filed: November 4, 2005
    Date of Patent: July 8, 2008
    Assignee: Theravance, Inc.
    Inventors: Seok-Ki Choi, Paul Fatheree, Roland Gendron, Adam A Goldblum, Lan Jiang, Daniel D Long, Daniel Marquess
  • Indazole-carboxamide compounds as 5-HT4 receptor agonists
    Publication number: 20080146807
    Abstract: The invention provides novel indazole-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: February 4, 2008
    Publication date: June 19, 2008
    Inventors: Daniel Marquess, Seok-Ki Choi, Paul R. Fatheree, Roland Gendron, Adam A. Goldblum, Daniel D. Long, S. Derek Turner, Jyanwei Liu
  • Indazole-carboxamide compounds
    Publication number: 20080132491
    Abstract: The invention provides novel indazole-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: January 15, 2008
    Publication date: June 5, 2008
    Inventors: Paul Fatheree, Roland Gendron, Adam A. Goldblum, Daniel D. Long, Daniel Marquess, S.Derek Turner, Seok-Ki Choi
  • Indazole-carboxamide compounds as 5-HTreceptor agonists
    Patent number: 7351704
    Abstract: The invention provides novel indazole-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Grant
    Filed: February 17, 2005
    Date of Patent: April 1, 2008
    Assignee: Theravance, Inc.
    Inventors: Daniel Marquess, Seok-Ki Choi, Paul R. Fatheree, Roland Gendron, Adam A. Goldblum, Daniel D. Long, S. Derek Turner, Jyanwei Liu
  • Benzoimidazolone-carboxamide compounds as 5-HT4 receptor agonists
    Publication number: 20080070923
    Abstract: The invention provides novel benzoimidazolone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: November 20, 2007
    Publication date: March 20, 2008
    Inventors: Roland Gendron, Seok-ki Choi, Paul Fatheree, Adam Goldblum, Daniel Long, Daniel Marquess, S. Turner
  • Benzoimidazolone-carboxamide compounds as 5-HTreceptors agonists
    Patent number: 7317022
    Abstract: The invention provides novel benzoimidazolone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Grant
    Filed: June 6, 2006
    Date of Patent: January 8, 2008
    Assignee: Theravance, Inc.
    Inventors: Roland Gendron, Seok-ki Choi, Paul R. Fatheree, Adam A. Goldblum, Daniel D. Long, Daniel Marquess, S. Derek Turner
  • Benzoimidazolone-carboxamide compounds as 5-HT4 receptors agonists
    Publication number: 20060276482
    Abstract: The invention provides novel benzoimidazolone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: June 6, 2006
    Publication date: December 7, 2006
    Inventors: Roland Gendron, Seok-ki Choi, Paul Fatheree, Adam Goldblum, Daniel Long, Daniel Marquess, S. Turner
  • Crystalline form of a benzimidazole-carboxamide medicinal compound
    Publication number: 20060270854
    Abstract: The invention provides crystalline forms of the novel benzimidazole-carboxamide 5-HT4 receptor agonist compound, 4-(4-{[(2-isopropyl-1H-benzoimidazole-4-carbonyl)amino]methyl}-piperidin-1-ylmethyl)piperidine-1-carboxylic acid methyl ester. The invention also provides pharmaceutical compositions comprising the crystalline compound, methods of using the compound to treat diseases associated with 5-HT4 receptor activity, and processes useful for preparing crystalline forms of the compound.
    Type: Application
    Filed: May 24, 2006
    Publication date: November 30, 2006
    Inventors: Sean Dalziel, Kirsten Phizackerley, Robert McKinnell, Roland Gendron, Seok-ki Choi, Daniel Long
  • Benzimidazole-carboxamide compounds as 5-HT4, receptor agonists
    Publication number: 20060270652
    Abstract: The invention relates to benzimidazole-carboxamide 5-HT4 receptor agonist compounds of formula (I) wherein R1 and X are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The invention also relates to pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: May 24, 2006
    Publication date: November 30, 2006
    Inventors: Robert McKinnell, Roland Gendron, Lan Jiang, Seok-ki Choi, Daniel Long, Paul Fatheree, Daniel Marquess
  • Quinolinone compounds as 5-HT4 receptor agonists
    Publication number: 20060199839
    Abstract: The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: March 1, 2006
    Publication date: September 7, 2006
    Inventors: Adam Goldblum, Seok-ki Choi, Paul Fatheree, Roland Gendron, Lan Jiang, Daniel Long, Daniel Marquess, S. Turner
  • Indazole-carboxamide compounds
    Publication number: 20060135764
    Abstract: The invention provides novel indazole-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: December 21, 2005
    Publication date: June 22, 2006
    Inventors: Paul Fatheree, Roland Gendron, Adam Goldblum, Daniel Long, Daniel Marquess, S. Derek Turner, Seok-Ki Choi
  • Quinolinone-carboxamide compounds
    Publication number: 20060100426
    Abstract: The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: November 4, 2005
    Publication date: May 11, 2006
    Inventors: Seok-Ki Choi, Paul Fatheree, Roland Gendron, Adam Goldblum, Lan Jiang, Daniel Long, Daniel Marquess
  • Indazole-carboxamide compounds as 5-HT4 receptor agonists
    Publication number: 20050197335
    Abstract: The invention provides novel indazole-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: February 17, 2005
    Publication date: September 8, 2005
    Inventors: Daniel Marquess, Seok-Ki Choi, Paul Fatheree, Roland Gendron, Adam Goldblum, Daniel Long, S. Derek Turner, Jyanwei Liu