Patents by Inventor Roland Hjerpe

Roland Hjerpe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ubiquitin binding polypeptides
    Patent number: 8716441
    Abstract: The invention relates to Tandem Ubiquitin Affinity Entities (TUBES) which are fusion polypeptides comprising at least two ubiquitin binding domains connected to each other by non-naturally occurring spacer regions. The TUBES are capable of binding with high affinity to ubiquitin and to ubiquitylated polypeptides and are therefore suitable for the purification of ubiquitylated polypeptides from cellular extracts as well as for the identification of new ubiquitylated polypeptides.
    Type: Grant
    Filed: February 20, 2009
    Date of Patent: May 6, 2014
    Assignee: Centro de Investigation Cooperativa en Biociencias—CIC BIOGUNE
    Inventors: Manuel Salvador Rodriguez Medina, Roland Hjerpe
  • UBIQUITIN BINDING POLYPEPTIDES
    Publication number: 20090220470
    Abstract: The invention relates to Tandem Ubiquitin Affinity Entities (TUBES) which are fusion polypeptides comprising at least two ubiquitin binding domains connected to each other by non-naturally occurring spacer regions. The TUBES are capable of binding with high affinity to ubiquitin and to ubiquitylated polypeptides and are therefore suitable for the purification of ubiquitylated polypeptides from cellular extracts as well as for the identification of new ubiquitylated polypeptides.
    Type: Application
    Filed: February 20, 2009
    Publication date: September 3, 2009
    Applicant: CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS - CIC bioGUNE
    Inventors: Manuel Salvador Rodriguez Medina, Roland Hjerpe