Abstract: A method for coating catheter balloons with a defined amount of a pharmacologically active agent, uses a coating device having a volume measuring device for releasing a measurable amount of a coating solution by means of a dispensing device specifically onto the surface of the catheter balloon.

Abstract: The embodiments described herein are directed to biodegradable stents comprising an inner biodegradable metal scaffold and an outer polymeric coating. The biodegradable coating consists preferentially of biodegradable polymers and may additionally include at least one pharmacologically active substance such as an anti-inflammatory, cytostatic, cytotoxic, antiproliferative, anti-microtubuli, antiangiogenic, antirestenotic (anti-restenosis), antifungicide, antineoplastic, antimigrative, athrombogenic and/or antithrombogenic agent.

Abstract: The invention relates to stents and catheter balloons having optimized coatings for eluting rapamycin as well as methods for manufacturing these coatings.

Abstract: The present invention relates to methods for coating the entire surface of lattice-like or mesh-like endoprostheses, wherein the endoprostheses initially are being provided with a thin layer covering the material surface of the endoprosthesis and subsequently, the surface of the entire endoprosthesis is being coated, wherein said coating of the entire surface covers the struts as well as the interstices between the individual struts.

Abstract: The invention concerns oligosaccharides and polysaccharides as well as the use of these oligosaccharides and/or polysaccharides, which contain the sugar unit N-acylglucosamine or N-acylgalactosamine for the production of hemocompatible surfaces as well as methods for the hemocompatible coating of surfaces with said oligosaccharides and/or polysaccharides, which imitate the common biosynthetic precursor substance of heparin, heparan sulphates and chitosan. The invention further describes methods for producing said oligosaccharides and/or polysaccharides and discloses various possibilities of using hemocompatibly coated surfaces. The invention relates particularly to the use of said oligosaccharides and/or polysaccharides on stents with at least one according to invention deposited hemocompatible coating, which contains an antiproliferative, antiinflammatory and/or antithrombotic active agent, methods for the preparation of said stents as well as the use of said stents for the prevention of restenosis.

Abstract: The invention relates to medical products with at least one biocompatible biostable polysulfone coating with which the elution kinetics of the incorporated and/or deposited at least one antiproliferative, antiinflammatory, antiphlogistic and/or antithrombotic active agent can be controlled via the admixing of at least one hydrophilic polymer in a suitable amount and as well as an local separation of different active agents and active agent combinations respectively can be achieved by means of the layer system of biostable polymers, methods of manufacturing these medical products as well as their use especially in the form of stents for prevention of restenosis.

Abstract: The invention relates to stents with at least one hemocompatible coating which contains an antiproliferative, antiinflammatory and/or antithrombotic active agent, methods for the preparation of said stents as well as the use of said stents for the prevention of restenosis.

Abstract: The invention relates to anti-thrombogenic surfaces and a process for making said surfaces. The process is primarily used for the anti-thrombogenic coating of hydrophobic surfaces of medical products coming into direct contact with blood and coagulable blood products.

Abstract: The invention relates to the use of polysaccharides, that comprise the sugar building unit N-acylglucosamine, for the preparation of hemocompatible surfaces as well as methods for the hemocompatible coating of surfaces with these polysaccharides, which are classified to be the common biosynthetic precursor substances of heparin and heparansulphates. Described are medical devices coated according to invention, especially stents, which comprise paclitaxel as antiproliferative active agent as well as the use of these stents for the prevention of restenosis.

Abstract: An adsorbent for whole blood in the form of essentially spherical non-aggregated particles. The adsorbent comprises a porous carrier material having an average pore size of ≦1.5 &mgr;m, whereby a maximum of 50% of the pore volume may be in pores having a pore size of >1.5 &mgr;m, whereby the outer surfaces of the porous carrier material have at least one surface modification M1 so that the outer surface essentially does not interact with blood cells, and the inner surfaces of the porous carrier material, e.g., the surfaces of the pores of the porous carrier material, have at least one surface modification M2 which interacts with substances present in blood.