Patents by Inventor Roland Jaunin

Roland Jaunin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ylidene sulfonamide derivatives
    Patent number: 4994612
    Abstract: Dihydropyridine derivatives of the formula ##STR1## wherein the symbols R and R.sup.1 to R.sup.6 have the significance given in claim 1, have a pronounced calcium-antagonist activity and can accordingly be used as medicaments, especially in the control or prevention of angina pectoris, ischemia, high blood pressure and/or migraine.
    Type: Grant
    Filed: April 11, 1989
    Date of Patent: February 19, 1991
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Roland Jaunin, Henri Ramuz
  • Dihydropyridine derivatives
    Patent number: 4847273
    Abstract: Dihydropyridine derivatives of the formula ##STR1## wherein the symbols R and R.sup.1 to R.sup.6 have the significance given in claim 1, have a pronounced calcium-antagonist activity and can accordingly be used as medicaments, especially in the control or prevention of angina pectoris, ischemia, high blood pressure and/or migraine.
    Type: Grant
    Filed: June 5, 1986
    Date of Patent: July 11, 1989
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Roland Jaunin, Henri Ramuz
  • Tetrahydronaphthalene derivatives as calcium antagonists
    Patent number: 4808605
    Abstract: Compounds of the formula ##STR1## wherein R is lower-alkyl, R.sup.1 is halogen, R.sup.2 is C.sub.1 -C.sub.12 -alkyl, R.sup.3 is hydroxy, lower-alkoxy, lower-alkyl-carbonyloxy, lower-alkoxy-lower-alkylcarbonoyloxy, lower-alkylaminocarbonyloxy, arylaminocarbonyloxy or aryl-lower alkylaminocarbonyloxy, X is C.sub.1 -C.sub.18 -alkylene which optionally can be interrupted by 1,4-phenylene or interrupted or lengthened by 1,4-cyclohexylene, A is di- or tri-substituted 2-imidazolyl attached via an ethylene group or a substituted or unsubstituted heterocycle selected from the group consisting of benzimidazolyl, benzimidazolonyl, imidazo[4,5-c]pyridinyl, imidazo[4,5-c]pyridinonyl, benzthiazolyl, benzodiazepine-2,5-dion-1-yl and pyrrolo[2,1-c]-[1,4]benzodiazepine-5,11-dion-10-yl and n is the number 0 or 1, in the form of racemates and optical antipodes, as well as N-oxides and pharmaceutically usable acid addition salts thereof.
    Type: Grant
    Filed: November 10, 1987
    Date of Patent: February 28, 1989
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Quirico Branca, Roland Jaunin, Hans P. Maki, Franzi Marti, Henri Ramuz
  • Sulfonamide containing dihydropyridine derivatives, intermediates and medicinal use
    Patent number: 4742069
    Abstract: Dihydropyridine derivatives of the formula ##STR1## wherein the symbols A, R and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 are as described herein.Compounds of formula I have a pronounced calcium-antagonistic activity and can accordingly be used as medicaments, especially for the control or prevention of angina pectoris, ischemia, high blood pressure and/or migraine.
    Type: Grant
    Filed: June 17, 1985
    Date of Patent: May 3, 1988
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Roland Jaunin, Henri Ramuz
  • Derivatives of 3-phenylisoindole-1-carboxylic acid
    Patent number: 4167632
    Abstract: Isoindole derivatives of the formula ##STR1## wherein A, Z, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8 and n are as hereinafter set forth, as well as intermediates, are described. The end products of formula I are useful as appetite-suppressants.
    Type: Grant
    Filed: July 26, 1978
    Date of Patent: September 11, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Roland Jaunin
  • Process and intermediates for isoindole derivatives
    Patent number: 4130717
    Abstract: A process for the preparation of isoindole derivatives which comprises heating a compound of the formula ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are as hereinafter set forth, in the presence of a suitable imidazole, is described.
    Type: Grant
    Filed: February 17, 1978
    Date of Patent: December 19, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Roland Jaunin
  • Derivatives of 3-phenylisoindole-1-carboxylic acid
    Patent number: 4122265
    Abstract: Isoindole derivatives of the formula ##STR1## wherein A, Z, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8 and n are as hereinafter set forth, as well as intermediates, are described. The end products of formula I are useful as appetite-suppressants.
    Type: Grant
    Filed: April 22, 1977
    Date of Patent: October 24, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Roland Jaunin
  • Process and intermediates for isoindole derivatives
    Patent number: 4089875
    Abstract: A process for the preparation of isoindole derivatives which comprises heating a compound of the formula ##STR1## wherein R,R.sub.1,R.sub.2,R.sub.3,R.sub.4 and R.sub.5 are hereinafter set forth, in the presence of a suitable imidazole, is described.
    Type: Grant
    Filed: July 7, 1977
    Date of Patent: May 16, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Roland Jaunin
  • Isoindole derivatives
    Patent number: 4090027
    Abstract: Isoindole derivatives of the formula ##STR1## wherein R.sub.1 -R.sub.6, A and Z are as hereinafter described. The isoindole derivatives are useful as appetite suppressants.
    Type: Grant
    Filed: August 25, 1976
    Date of Patent: May 16, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Roland Jaunin
  • Isoindole derivatives
    Patent number: 4077978
    Abstract: Isoindole derivatives of the formula ##STR1## wherein R.sub.1 -R.sub.6, A and Z are as hereinafter described. The isoindole derivatives are useful as appetite suppressants.
    Type: Grant
    Filed: August 25, 1976
    Date of Patent: March 7, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Roland Jaunin
  • Isoindole derivatives as appetite suppressants
    Patent number: 3996374
    Abstract: Isoindole derivatives of the formula ##STR1## wherein R.sub.1 -R.sub.6, A and Z are as hereinafter described. The isoindole derivatives are useful as appetite suppressants.
    Type: Grant
    Filed: November 20, 1975
    Date of Patent: December 7, 1976
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Roland Jaunin