Abstract: A pump dispenser for metered removal of a liquid from a container includes a housing for placement on the container to form a metering chamber, a rising tube connected to the metering chamber, and a pump head movable relative to the housing along a longitudinal axis of the dispenser to carry out a pump stroke. The pump dispenser has a piston secured to the pump head that is movable in the metering chamber to convey the liquid, a dispenser opening is connected to the metering chamber through which metered liquid can leave the pump dispenser, a spring that resets the pump head relative to the housing, and a valve that defines a conveying direction of the liquid from the rising tube into the dispenser opening and that blocks a conveying process in the opposite direction. The spring has a plurality of rings connected by respective connecting webs.

Abstract: The invention relates to a handle for a wet razor including a handle section as well as a coupling section for detachably attaching a cutting unit to the handle. The coupling section comprises a housing section including a housing cavity, which has an insertion opening at the end directed toward the cutting unit and an operating opening. The coupling section furthermore comprises a connector including fastening elements, which engage in the housing section, and including a peg, which protrudes beyond the plane of the insertion opening. The coupling section furthermore comprises an ejector, which is inserted into the housing cavity so as to be axially displaceable, including a spring element, which axially urges the ejector into the housing cavity, and a ram, which during axial displacement of the ejector in the direction toward the cutting unit extends beyond the plane of the insertion opening.

Abstract: The invention relates to a novel pump device for a fluid container for dispensing a fluid, which device has an operating element and a head part, wherein a piston-cylinder unit forming a pump chamber is provided between the operating element and the head part. An inlet valve is provided at the inlet of the pump chamber, and an outlet valve is provided at the outlet of the pump chamber, wherein the operating element has an outflow with an outflow opening. The outlet valve is also provided at the outflow, and the outflow opening forms a valve seat in such a way that the outlet valve closes the outlet opening from outside.

Abstract: The present invention relates to molecules interfering with the function of neuropilin-1 in the context of angiogenesis and the treatment of cancer. Molecules, polypeptides, antibodies, compositions and methods are provided that are useful for reducing, inhibiting or treating angiogenesis, the invasion of blood vessels into tumors, and/or the invasion or the metastatic potential of specific tumor cells. Additionally, a method is provided that allows identifying molecules, which interfere with the functionality of neuropilin-1. Furthermore, a method is provided that allows determining whether a naturally occurring tumor cell depends on functional neuropilin-1 for its invasiveness and/or metastatic potential.

Abstract: The invention relates to a dispenser pump (1), for the non-dropping, dosed dispensing of liquid to pasty products from containers, for example, from bottles, canisters, or tubes, comprising a pump lower section (6) with a suction opening (4) and a pump upper section (8) with a moving lid (10), for sucking up the product through the suction opening (4) of the pump lower section (6) into a suction chamber (14) and to dispense the product from said suction chamber (14), through a dispensing channel (3) with an application opening (24).

Abstract: The invention relates to a dispenser pump (1), for the non-dropping, dosed dispensing of liquid to pasty products from containers, for example, from bottles, canisters, or tubes, comprising a pump lower section (6) with a suction opening (4) and a pump upper section (8) with a moving lid (10), for sucking up the product through the suction opening (4) of the pump lower section (6) into a suction chamber (14) and to dispense the product from said suction chamber (14), through a dispensing channel (3) with an application opening (24).

Abstract: The present invention relates to molecules interfering with the function of neuropilin-1 in the context of angiogenesis and the treatment of cancer. Molecules, polypeptides, antibodies, compositions and methods are provided that are useful for reducing, inhibiting or treating angiogenesis, the invasion of blood vessels into tumors, and/or the invasion or the metastatic potential of specific tumor cells. Additionally, a method is provided that allows identifying molecules, which interfere with the functionality of neuropilin-1. Furthermore, a method is provided that allows determining whether a naturally occuring tumor cell depends on functional neuropilin-1 for its invasiveness and/or metastatic potential.