Patents by Inventor Roland L. Dunbrack

Roland L. Dunbrack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimera of bone morphogenic protein 2 and the Müllerian-inhibiting substance type II receptor binding region of Müllerian-inhibiting substance
    Patent number: 11261225
    Abstract: Recombinant proteins that comprise a bone morphogenic protein 2 backbone onto which was grafted a Müllerian-inhibiting substance type II receptor binding region of the Müllerian-inhibiting substance protein are provided. These proteins bind to this receptor on the surface of epithelial cancer cells, and induce apoptosis of such cells. These proteins are useful, for example, in the treatment of cancers such as ovarian, uterine, endometrial, fallopian tube, breast, prostate, and lung cancers.
    Type: Grant
    Filed: February 12, 2018
    Date of Patent: March 1, 2022
    Assignee: INSTITUTE FOR CANCER RESEARCH
    Inventors: Roland L. Dunbrack, Jared Adolf-Bryfogle, Gregory P. Adams, Matthew K. Robinson
  • Chimera of Bone Morphogenic Protein 2 and the Mullerian-Inhibiting Substance Type II Receptor Binding Region of Mullerian-Inhibiting Substance
    Publication number: 20200010523
    Abstract: Recombinant proteins that comprise a bone morphogenic protein 2 backbone onto which was grafted a Müllerian-inhibiting substance type II receptor binding region of the Müllerian-inhibiting substance protein are provided. These proteins bind to this receptor on the surface of epithelial cancer cells, and induce apoptosis of such cells. These proteins are useful, for example, in the treatment of cancers such as ovarian, uterine, endometrial, fallopian tube, breast, prostate, and lung cancers.
    Type: Application
    Filed: February 12, 2018
    Publication date: January 9, 2020
    Inventors: Roland L. Dunbrack, Jared Adolf-Bryfogle, Gregory P. Adams, Matthew K. Robinson