Patents by Inventor Roland Maier

Roland Maier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4370327
    Abstract: The invention is directed to cephalosporins of the formula ##STR1## and the tautomers thereof, and, when E is a hydrogen atom, the pharmacologically acceptable salts thereof with inorganic or organic bases.
    Type: Grant
    Filed: February 23, 1981
    Date of Patent: January 25, 1983
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Bernd Wetzel, Eberhard Woitun, Wolfgang Reuter, Roland Maier, Uwe Lechner, Hanns Goeth
  • Patent number: 4364944
    Abstract: Compounds of the formula ##STR1## wherein Y is hydrogen or methoxy;A is ##STR2## or, when Y is methoxy, also phenyl, 4-hydroxy-phenyl, 2-thienyl, 3-thienyl of 3,4-dihydroxy-phenyl;A' is hydrogen, --COCH.sub.2 Cl, --COCH.sub.2 Br, --COOCH.sub.2 CCL.sub.3, formyl or trityl;D is hydrogen, acetoxy, aminocarbonyloxy, pyridinium, 4-aminocarbonyl-pyridinium or -S-Het, where Het is 3-methyl-1,2,4-thiadiazol-5-yl, 1,2,4-thiadiazol-5-yl, 1,3,4-thiadiazol-5-yl, 2-methyl-1,3,4-thiadiazol-5-yl, 4H-5,6-dioxo-1,2,4-triazine-3-yl, 4-methyl-5,6-dioxo-1,2,4-triazin-3-yl, 1-vinyl-tetrazol-5-yl, 1-allyl-tetrazol-5-yl or ##STR3## n is 1, 2 or 3; R.sub.1 is hydroxyl, amino, dimethylamino, acetylamino, aminocarbonyl, aminocarbonylamino, aminosulfonyl, aminosulfonylamino, methylcarbonyl, methylsulfonylamino, cyano, hydroxysulfonylamino, methylsulfonyl, methylsulfinyl, a carboxylic acid group or a sulfonic acid group; or--(CH.sub.2).sub.n R.sub.1 is alkyl of 1 to 4 carbon atoms or 2,3-dihydroxy-propyl;R.sub.
    Type: Grant
    Filed: November 20, 1981
    Date of Patent: December 21, 1982
    Assignee: Dr. Karl Thomae Gesellschaft mit beschrankter Haftung
    Inventors: Bernd Wetzel, Eberhard Woitun, Wolfgang Reuter, Roland Maier, Uwe Lechner, Hanns Goeth
  • Patent number: 4362725
    Abstract: Compounds of the formula ##STR1## wherein A is phenyl, 4-hydroxy-phenyl, 2-thienyl, 2-furyl or 3,4-dihydroxy-phenyl;Y is hydrogen or methoxy;Het is 4H-5,6-dioxo-1,2,4-triazin-3-yl,4-methyl-5,6-dioxo-1,2,4-triazin-3-yl,2-methyl-5,6-dioxo-1,2,4-triazin-3-yl,1-vinyl-tetrazol-5-yl, 1-allyl-tetrazol-5-yl or ##STR2## where n is an integer from 1 to 3, inclusiveR.sub.1 is hydroxyl, amino, dimethylamino, acetylamino, aminocarbonyl, aminocarbonylamino, aminosulfonyl, aminosulfonylamino, methylcarbonyl, methylsulfonylamino, cyano, hydroxysulfonylamino, methylsulfonyl, methylsulfinyl, a carboxylic acid group or a sulfonic acid group, and--(CH.sub.2).sub.n --R.sub.1 may also be alkyl of 2 to 4 carbon atoms or 2,3-dihydroxy-propyl;R is cyclopropyl, 4'-hydroxycyclohexyl-amino ##STR3## where R.sub.
    Type: Grant
    Filed: September 28, 1981
    Date of Patent: December 7, 1982
    Assignee: Dr. Karl Thomae Gesellschaft mit beschrankter Haftung
    Inventors: Bernd Wetzel, Eberhard Woitun, Wolfgang Reuter, Roland Maier, Uwe Lechner, Hanns Goeth
  • Patent number: 4316898
    Abstract: Cephalosporins of the formula ##STR1## wherein A is phenyl, 4-hydroxyphenyl, cyclohexyl, cyclohexene-1-yl, cyclohexa-1,4-diene-1-yl, 2-thienyl, 3-thienyl, 2-furyl, 3-furyl or 3,4-disubstituted phenyl, where the substituents, which may be identical to or different from each other, are each chlorine, hydroxyl or methoxy;Y is hydrogen or methoxy;D is hydrogen, hydroxyl, acetoxy, aminocarbonyloxy, pyridinium, aminocarbonyl-pyridinium or the group S-Het, where Het is 1-methyl-tetrazol-5-yl, tetrazol-5-yl, 3-methyl-1,2,4-thiadiazol-5-yl, 1,2,4-thiadiazol-5-yl, 1,3,4-thiadiazol-5-yl, 2-methyl-1,3,4-thiadiazol-5-yl, 2-methylamino-1,3,4-thiadiazol-5-yl, 2-dimethylamino-1,3,4-thiadiazol-5-yl, 2-formylamino-1,3,4-thiadiazol-5-yl, 2-acetylamino-1,3,4-thiadiazol-5-yl, 2-methyl-1,3,4-oxadiazol-5-yl, 1,2,3-triazol-4-yl or 1,2,4-triazol-3-yl;R is hydrogen, methyl, cyclopropyl, hydroxyl, methoxy, ethoxy, mercapto, morpholino, thiomorpholino, thiomorpholino-S-oxide, thiomorpholino-S,S-dioxide, ##STR2## E is hydrogen or a prote
    Type: Grant
    Filed: May 20, 1980
    Date of Patent: February 23, 1982
    Assignee: Boehringer Ingelheim KG
    Inventors: Bernd Wetzel, Eberhard Waitun, Roland Maier, Wolfgang Rueter, Uwe Lechner, Hans Goeth
  • Patent number: 4289775
    Abstract: Compounds of the formula ##STR1## wherein A is phenyl, p-hydroxy-phenyl, 2-thienyl, 3-thienyl or 3,4-disubstituted phenyl, where the substituents, which may be identical to or different from each other, are each chlorine, hydroxyl or methoxy;R is --NH--Z--X;Z is straight or branched alkylene of 1 to 6 carbon atoms or cycloalkylene of 3 to 6 carbon atoms;X is cyano, hydroxyl, mercapto, aminocarbonyl, aminosulfonyl, ##STR2## R.sub.1 is straight or branched alkyl of 1 to 4 carbon atoms or phenyl; R.sub.2 is hydrogen or alkyl of 1 to 4 carbon atoms; andR.sub.1 and R.sub.2, together with an adjacent nitrogen atom to which they are attached, form a 3- to 6-membered heterocyclic ring;and non-toxic, pharmacologically acceptable salts thereof formed with inorganic or organic bases.
    Type: Grant
    Filed: May 14, 1980
    Date of Patent: September 15, 1981
    Assignee: Karl Thomae GmbH
    Inventors: Bernd Wetzel, Eberhard Woitun, Wolfgang Reuter, Roland Maier, Uwe Lechner, Hanns Goeth
  • Patent number: 4256738
    Abstract: Compounds of the formulaR--NH--(CH.sub.2).sub.n --NH--EwhereinR is a pyrimidinyl, a quinazolinyl, a 5,6,7,8-tetrahydro-quinazolinyl, a thieno[3,2,-d]pyrimidinyl, a thieno[2,3-d]pyrimidyl, a pyrido[3,2-d]primidinyl, a 5,6-dihydro-4-pyrido[3,4-d]pyrimidinyl, an isothiazola [5,4-d]pyrimidinyl or a pyrimido[4,5-d]-pyrimidinyl group;n is 2 or 3; andE is the 9-erythromycyl group;and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as antibacterials.
    Type: Grant
    Filed: November 3, 1978
    Date of Patent: March 17, 1981
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Eberhard Woitun, Bernd Wetzel, Roland Maier, Wolfgang Reuter, Uwe Lechner, Rolf G. Werner, Hanns Goeth
  • Patent number: 4250765
    Abstract: A force transmitting arrangement, useable as force amplifier of drive arrangements, transmits the moment of a reversible electric motor, acting as a servo motor or as a drive motor, over a friction core and a looped spring cooperating therewith to an output shaft. The looped spring has a pair of outwardly bent ends, which at the outer sides thereof drive, while taking up a tension force, an output entrainment member connected to the output shaft, whereas an input entrainment member connected with a manually operated drive, for instance the steering wheel of a motor vehicle, is located between the outwardly bent ends of the looped spring.
    Type: Grant
    Filed: January 17, 1979
    Date of Patent: February 17, 1981
    Assignee: Robert Bosch GmbH
    Inventors: Bernd Niklaus, Manfred Braun, Roland Maier
  • Patent number: 4241056
    Abstract: Compounds of the formula ##STR1## wherein A is phenyl; 4-hydroxy-phenyl; 2- or 3-thienyl; cyclohexyl; cyclohexen-1-yl; cyclohexa-1, 4-dien-1-yl; or 3,4-disubstituted phenyl, where the substituents may be identical to or different from each other and are selected from the group consisting of chlorine, hydroxyl or methoxy; andR is an aliphatic, cycloaliphatic; aromatic or heterocyclic group of diverse types;and non-toxic, pharmacologically acceptable salts thereof formed with inorganic or organic bases. The compounds as well as their salts are useful as antibiotics.
    Type: Grant
    Filed: February 21, 1979
    Date of Patent: December 23, 1980
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Bernd Wetzel, Wolfgang Reuter, Eberhard Woitun, Roland Maier, Uwe Lechner, Hanns Goeth, Rolf Werner
  • Patent number: 4173647
    Abstract: The compound of the formula ##STR1## and non-toxic, pharmacologically acceptable acid addition salts thereof. The compound as well as its salts are useful as antimicrobials.
    Type: Grant
    Filed: December 4, 1978
    Date of Patent: November 6, 1979
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Roland Maier, Eberhard Woitun, Wolfgang Reuter, Bernd Wetzel, Hanns Goeth, Uwe Lechner
  • Patent number: 4048306
    Abstract: The invention relates to novel erythromycin derivatives, and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as the salts are useful as antibacterials.
    Type: Grant
    Filed: March 29, 1976
    Date of Patent: September 13, 1977
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Roland Maier, Eberhard Woitun, Bernd Wetzel, Wolfgang Reuter, Hanns Goeth, Uwe Lechner
  • Patent number: 4016263
    Abstract: Compounds of the formula ##STR1## wherein E is ##STR2## R.sub.1 is hydrogen; straight or branched alkyl of 1 to 3 carbon atoms; (alkoxy of 1 to 5 carbon atoms)-(alkyl of 1 to 3 carbon atoms); phenyl; or benzyl;R.sub.2 is hydrogen; hydroxyl; straight or branched alkyl of 1 to 3 carbon atoms; or phenyl;R.sub.
    Type: Grant
    Filed: March 29, 1976
    Date of Patent: April 5, 1977
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Bernd Wetzel, Eberhard Woitun, Roland Maier, Wolfgang Reuter, Hanns Goeth, Uwe Lechner