Abstract: In a suturing instrument for remote suturing of the edges of tissue wherein a stationary and a pivotal jaw are arranged at the distal end of an instrument shaft and a suturing wire guide channel extends through the instrument shaft for supplying a suturing wire from the instrument's proximal end to the stationary jaw and wherein an outer tube is movably disposed on the instrument shaft for engaging the pivotal jaw to move it toward and from the stationary jaw and hold the jaws in an operating position in which they are arranged parallel to one another, the jaws have spaced wire guide grooves with groove bases defining, in the operating position of the jaws, a screw line which is followed by the suturing wire when it is advanced by advancing means operated by a handle disposed at the proximal end of the suturing instrument.