Abstract: In an off-set printing device suited to multi-colored printing the printing plate support and the printing carrier support are arranged on a common carrier plate between two parallel racks connected with the carrier plate and extending in the printing direction. The printing roller is freely removable from the carrier plate and has at each of its axial ends a spur gear or pinion for engagement with an associated one of the racks, and the roll of the printing roller is freely rotatable relative to a shaft provided with hand grips. On the carrier plate--in the printing direction--in front of the printing plate support and on the printing roller at least one projection and a complementary recess are provided which in the presenting of the printing roller to the carrier plate engage with one another.