Patents by Inventor Roland W. Bürli

Roland W. Bürli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibacterial compounds having a (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) motif
    Patent number: 7129214
    Abstract: Compounds of the formula (I) where Ar and R are as defined herein, possess antibacterial properties.
    Type: Grant
    Filed: December 9, 2003
    Date of Patent: October 31, 2006
    Assignee: Oscient Pharmaceuticals Corporation
    Inventors: Wenhao Hu, Roland W. Bürli
  • Halogen-substitued thienyl compounds
    Patent number: 7122626
    Abstract: Halogen substituted thienyl compounds exhibit potential as nucleic acid (especially double stranded DNA) binders and as antibiotic compounds.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: October 17, 2006
    Assignee: GeneSoft Pharmceuticals, Inc.
    Inventors: Yigong Ge, Matthew J. Taylor, Eldon E. Baird, Roland W. Bürli, Jacob A. Kaizerman, Amanda E. Martin, Brie Cadman
  • Charged compounds comprising a nucleic acid binding moiety and uses therefor
    Patent number: 7078536
    Abstract: Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing such compounds, methods of screening such compounds to identify those having anti-infective activity, and methods of using such compounds to prevent or inhibit infections. These compounds, and compositions containing them, have multiple applications, including use in human and animal medicine and in agriculture.
    Type: Grant
    Filed: October 22, 2002
    Date of Patent: July 18, 2006
    Assignee: Genesoft Pharmaceuticals, Inc.
    Inventors: Yigong Ge, Matthew J. Taylor, Eldon E. Baird, Heinz E. Moser, Roland W. Bürli
  • Benzothiophene compounds having antiinfective activity
    Patent number: 6825228
    Abstract: Benzothiophene compounds such as are DNA binding compounds exhibiting antibacterial activity.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: November 30, 2004
    Assignee: Genesoft Pharmaceuticals, Inc.
    Inventors: Roland W. Bürli, Eldon E. Baird, Matthew J. Taylor, Jacob A. Kaizerman, Wenhao Hu
  • Isoquinoline compounds having antiinfective activity
    Patent number: 6777425
    Abstract: Isoquinoline compounds having the formula where R1, R2, Y, m, n, and Z are as defined herein, bind to the minor groove of DNA and have antifungal and antibacterial activity.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: August 17, 2004
    Assignee: Genesoft Pharmaceuticals, Inc.
    Inventors: Roland W. Bürli, Peter Jones, Jacob A. Kaizerman, Wenhao Hu
  • Aryl-benzimidazole compounds having antiinfective activity
    Patent number: 6716866
    Abstract: Aryl-benzimidazole compounds according to the formula where Ar1, R1, R2, Y, W, and N are as defined herein, bind to DNA and have antibacterial activity.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: April 6, 2004
    Assignee: GeneSoft Pharmaceuticals, Inc.
    Inventors: Dustin L. McMinn, Roland W. Bürli, Jacob Kaizerman, Eldon E. Baird, Matthew J. Taylor
  • Charged compounds comprising a nucleic acid binding moiety and uses therefor
    Patent number: 6555693
    Abstract: Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing such compounds, methods of screening such compounds to identify those having anti-infective activity, and methods of using such compounds to prevent or inhibit infections. These compounds, and compositions containing them, have multiple applications, including use in human and animal medicine and in agriculture.
    Type: Grant
    Filed: March 14, 2001
    Date of Patent: April 29, 2003
    Assignee: Genesoft, Inc.
    Inventors: Yigong Ge, Matthew J. Taylor, Eldon E. Baird, Heinz E. Moser, Roland W. Bürli