Abstract: The present disclosure is directed to capsules, for example, softgel capsules for oral administration that have on their surface laser etching that penetrates at least partially into the surface of the capsule, reduces the structural integrity of the capsule while preventing exposure of the interior contents to the outside environment, and increases the rate of release of active ingredients contained within.

Abstract: A composition is made by melt-mixing pellets and a further propylene-based polymer, wherein the pellets are pellets of a glass fiber-reinforced thermoplastic polymer composition having a sheathed continuous multifilament strand including a core that extends in the longitudinal direction and a polymer sheath which intimately surrounds said core, wherein the core includes at least one continuous glass multifilament strand, the polymer sheath has a thermoplastic polymer composition containing a polyolefin and having a melt flow index as measured according to ISO 1133-1:2011 (2.16 kg/230° C.) of at least 1.0 dg/min and less than 47 dg/min, wherein the length of the glass filaments in the pellets is substantially the same as the pellet length, and is 10 to 55 mm, wherein the further polyolefin has a melt flow index as measured according to ISO 1133-1:2011 (2.16 kg/230° C.) of less than 20 dg/min.

Abstract: A protective housing for a microtome blade (4) includes a frame that holds the microtome blade (4) and a clip (2) that can be pivoted relative to the frame. In a first position, the clip (2) covers a cutting edge of the microtome blade (4) received in the frame. A microtome blade holder (6) is configured to receive an arrangement (100) composed of the protective housing and the microtome blade (4).

Abstract: A method of producing thin sections using a microtome is disclosed. A hand wheel (32) is manually driven for producing a first thin section, and wherein the rotational movement of the hand wheel (32) is detected by an encoder (38), and a profile of the rotational movement is determined. The determined profile is stored and selected for production of at least a second thin section. A motor (24) is driven for generating a cutting movement between a cutting unit (16) and a sample holder (12) in accordance with the respective stored profile selected for producing the second thin section. A microtome (10) to carry out this method is also disclosed.

Abstract: The present invention relates to a microtome (10) for cutting thin sections, including a sample holder (12), a cutting unit (16), and a drive unit (16) for producing a feed movement between the sample holder (12) and the cutting unit (16) for setting the thickness of the sample sections. The drive unit (22) includes a piezoelectric linear actuator (50) for producing the feed movement.

Abstract: The present invention relates to a method of producing thin sections by means of a microtome, wherein a hand wheel (32) is manually driven for producing a first thin section, and wherein the rotational movement of the hand wheel (32) is detected by means of an encoder (38), and a profile of the rotational movement is determined. The determined profile is stored and selected for production of at least a second thin section. A motor (24) is driven for generating a cutting movement between a cutting unit (16) and a sample holder (12) in accordance with the respective stored profile selected for producing the second thin section. The invention further relates to a microtome (10) by means of which the above method is carried out.

Abstract: A pipe cutting apparatus (10), especially for cutting or machining a plastics, resin or soft-metallic pipe (20), comprises a frame (30a, 30b; 32a, 32b) for receiving the pipe (20) to be cut, and cutting means (102) rotatable by externally powered drive means (60) with respect to the pipe (20) to perform a cut, wherein the cutting means (102) comprises a cutting tool (102) carried on a pivotally mounted tool holder (100) and biased into cutting relationship with the outer surface of the pipe (20) by biasing means such as a coil spring (104).

Abstract: The invention relates to a knife holder (100) having a blade changing apparatus (102). The knife holder has a first blade receptacle (111) defining a cutting position, a securing device (130, 141, 142) for securing a blade (201) received in the first blade receptacle (111), a second blade receptacle (112) defining an output position, and an ejection device (141, 143, 144a) for ejecting a blade (201) received in the first blade receptacle (111) out of the first blade receptacle (111). The first and the second blade receptacles are arranged in the knife holder in such a way that a blade ejected from the first blade receptacle (111) can travel by gravity into the second blade receptacle (112).

Abstract: A blade dispenser (100) has a blade supply container (110), a blade disposal container (120), and a detachable and reconnectable connecting means (130, 131, 132) that is embodied to connect the blade supply container (110) and blade disposal container (120) detachably to one another. The blade supply container (110) has a blade supply container upper side and a blade supply container underside, and is embodied to receive a blade stack (111) made up of multiple mutually abutting blades (112, 115). The blade supply container (110) also has a removal opening (116) through which at least one blade (112, 115) of the blade stack (111) is removable from the blade supply container (110). The blade disposal container (120) has a blade disposal container upper side and a blade disposal container underside, and is embodied to receive blades (120) to be disposed of.

Abstract: The present invention relates to a microtome (10) including a sample holder (12) a cutting unit (16), and a drive unit (22) capable of producing a relative movement between the sample holder (12) and the cutting unit (16) for cutting the sample. In addition, the microtome (10) has a handwheel (32) and an encoder (38). A control unit (40) controls the drive unit (22) as a function of the rotational movement of the handwheel (32) detected by the encoder (38) and in such a way that, in a first operating mode, the relative movement produced between the sample holder (12) and the cutting element (16) by the drive unit (22) when the handwheel (32) is rotated through a full revolution has a maximum first stroke length and that, in a second operating mode, the relative movement has a preset second stroke length shorter than the maximum first stroke length.

Abstract: A method and a device for producing thin sections of a sample by means of a microtome is described, in which a camera acquires at least one image of a surface generated by sectioning of the sample. With the aid of an evaluation device, the image of the surface is evaluated in terms of predefined characteristic values of a section quality. As a function of the characteristic values that are identified, a decision is then made as to whether the section of the sample is accepted or not.

Abstract: The invention relates to a knife holder (100) having a blade changing apparatus (102). The knife holder has a first blade receptacle (111) defining a cutting position, a securing means (130, 141, 142) for securing a blade (201) received in the first blade receptacle (111), a second blade receptacle (112) defining an output position, and an ejection means (141, 143, 144a) for ejecting a blade (201) received in the first blade receptacle (111) out of the first blade receptacle (111). The first and the second blade receptacles are arranged in the knife holder in such a way that a blade ejected from the first blade receptacle (111) can travel by gravity into the second blade receptacle (112).

Abstract: A blade dispenser (100) has a blade supply container (110), a blade disposal container (120), and a detachable and reconnectable connecting means (130, 131, 132) that is embodied to connect the blade supply container (110) and blade disposal container (120) detachably to one another. The blade supply container (110) has a blade supply container upper side and a blade supply container underside, and is embodied to receive a blade stack (111) made up of multiple mutually abutting blades (112, 115). The blade supply container (110) also has a removal opening (116) through which at least one blade (112, 115) of the blade stack (111) is removable from the blade supply container (110). The blade disposal container (120) has a blade disposal container upper side and a blade disposal container underside, and is embodied to receive blades (120) to be disposed of.

Abstract: The present invention relates to a microtome (10) for cutting thin sections, including a sample holder (12), a cutting unit (16), and a drive unit (16) for producing a feed movement between the sample holder (12) and the cutting unit (16) for setting the thickness of the sample sections. The drive unit (22) includes a piezoelectric linear actuator (50) for producing the feed movement.

Abstract: The present invention relates to a microtome (10) including a sample holder (12) a cutting unit (16), and a drive unit (22) capable of producing a relative movement between the sample holder (12) and the cutting unit (16) for cutting the sample. In addition, the microtome (10) has a handwheel (32) and an encoder (38). A control unit (40) controls the drive unit (22) as a function of the rotational movement of the handhweel (32) detected by the encoder (38) and in such a way that, in a first operating mode, the relative movement produced between the sample holder (12) and the cutting element (16) by the drive unit (22) when the handwheel (32) is rotated through a full revolution has a maximum first stroke length and that, in a second operating mode, the relative movement has a preset second stroke length shorter than the maximum first stroke length.

Abstract: A method of cutting at least one thin section from a sample block that is arranged in a cassette and tagging at least one specimen slide such that it can be allocated to the specific sample block from which the thin section has been cut. The method includes removing a cassette from a cassette magazine; reading the machine-readable coded information of the cassette identifier; generating by at least one tagging unit a specimen slide identifier that interrelates to the cassette identifier read by the reading unit; inserting the cassette into a microtome; transferring data from the microtome to a tagging unit via a data transfer path while the cassette is inserted into the microtome; enabling tagging of the specimen slide; tagging the specimen slide by the tagging unit; and cutting the thin section and transferring it onto the specimen slide that was tagged by the tagging unit.

Abstract: A method of cutting at least one thin section from a sample block that is arranged in a cassette and tagging at least one specimen slide such that it can be allocated to the specific sample block from which the thin section has been cut. The method includes removing a cassette from a cassette magazine; reading the machine-readable coded information of the cassette identifier; generating by at least one tagging unit a specimen slide identifier that interrelates to the cassette identifier read by the reading unit; inserting the cassette into a microtome; transferring data from the microtome to a tagging unit via a data transfer path while the cassette is inserted into the microtome; enabling tagging of the specimen slide; tagging the specimen slide by the tagging unit; and cutting the thin section and transferring it onto the specimen slide that was tagged by the tagging unit.

Abstract: An apparatus and method for tagging a specimen slide are described. The apparatus comprises a receiving region for receiving at least one cassette magazine, a reading unit for reading the machine-readable coded information of a cassette identifier of a cassette, and a tagging unit for generating a machine-readable coded information for tagging the specimen slide with a specimen slide identifier that depends on the cassette identifier. Data are transferred from the microtome to the apparatus via the data transfer path as soon as the cassette is inserted into the microtome, and only then can the machine-readable coded information for tagging the specimen slide be applied onto the specimen slide by the tagging unit.

Abstract: The invention relates to a method for operating an electric motor (2) having a phase angle control with the following steps: Applying an AC voltage to a series connection of the electric motor (2) and a switching element (4), particularly a triac, wherein the switching element (4) connects through by applying an ignition signal and suppresses the flow of a current if the amount of current falls below a holding current; determining the time of a zero crossing of a virtual motor current that would flow if the switching element (4) were connected through; and turning on the switching element (4) at an activation time that is dependant on the time of the zero crossing of the virtual motor current.

Abstract: The present invention relates to a device for braking or locking a shaft (6) of a microtome (1). The microtome (1) comprises the shaft (6), an actuating element (2), a movement mechanism (37) and a housing (38). With the movement mechanism (37) an object to be cut can be moved relative to a knife blade. The actuating element (2) can be manually actuated by an operator. As a result thereof, the shaft (6) can be rotated. Via the shaft (6), the movement mechanism (37) for performing the relative motion between the object and the knife blade can be driven. Further, the present invention relates to a method for operating a device for braking a shaft (6) of a microtome (1). So that the device can be used in a mechanically formed movement mechanism (37), the inventive device is characterized by an actuator and a braking unit (25). The braking unit (25) is connected in a rotatably fixed manner to the shaft (6).