Abstract: A semiconductor device has a substrate having a first plurality of substrate bonding pads disposed on a bonding surface thereof. A plurality of semiconductor dice is disposed on the substrate. Each die of the plurality of dice has a first plurality of die bonding pads arranged along at least one first edge thereof. A plurality of bonding pillars extends substantially vertically from the substrate bonding pads. Each bonding pillar electrically connects one of the first plurality of substrate bonding pads to a corresponding one of the first plurality of die bonding pads. A method of assembling a semiconductor device is also described.

Abstract: A chassis measuring system comprises an illumination device for producing a structured illumination (38, 58, 78, 98), which is developed in such a way that it produces a structured image on a measuring head (32, 52; 72, 92) situated opposite in the transverse vehicle direction, a reference surface (40, 60, 80, 100) facing in the same direction as the illumination device (38, 58, 78, 98), on which a structured image produced by an illumination device (38, 58; 78, 98) of the measuring head (32, 52; 72, 92) situated opposite in the transverse vehicle direction may be projected, and at least one measuring camera (34, 36; 54, 56; 74, 76; 94, 96) facing in the same direction as the illumination device (38, 58, 78, 98), which is developed in such a way that it detects the structured image on the reference surface (40, 60; 80, 100) of the opposite measuring head (32, 52; 72, 92) in order to determine the position parameters of the measuring head (32, 52, 72, 92).

Abstract: Alkyl ether sulfates having 1 to 9 carbon atoms in the alkyl chain and 1 to 20 alkyleneoxy units in the ether moiety are suitable for use as low-foam additives for enhancing the activity of water-soluble or partially water-soluble agrochemicals. They can be used to produce low-foam preparations for crop protection.

Abstract: An optical coupler for coupling optical-pump power into a multimode fiber configured to transport an optical space-division-multiplexed (SDM) signal, the coupling being performed in a manner that enables amplification of the SDM signal in the multimode fiber via a stimulated-emission process or a stimulated Raman-scattering process. The optical coupler can be a part of an optical transmitter configured for co-directional pumping, an optical receiver configured for contra-directional pumping, or a relay station disposed within an optical communication link and configured for either type of pumping. The optical coupler can advantageously be used, e.g., to offset the different degrees of attenuation to which the SDM-signal components corresponding to different guided modes of the multimode fiber are subjected to therein.

Abstract: A package for a portion of liquid foodstuff dilutable with a diluent includes a reservoir for containing a portion of liquid foodstuff dilutable with a diluent, a reservoir seal for closing the reservoir, a mixing element for mixing the dilutable liquid foodstuff with the diluent. The mixing element includes a mixing chamber having an outflow aperture for dispensing liquid foodstuff diluted with the diluent, a liquid passage for feeding dilutable liquid foodstuff from the reservoir to the mixing chamber, and a feed channel for feeding diluent to the mixing chamber. The feed channel has a first portion and a second portion, the cross section of the second portion being smaller than the cross section of the first portion and be so configured that when diluent is fed to the mixing chamber, a venturi effect occurs in the mixing chamber.

Abstract: Disclosed is a method of administering an interleukin-2 receptor (IL-2R) antagonist to a subject to treat an autoimmune disease. In particular embodiments, the IL-2R antagonist is an anti-IL-2R monoclonal antibody specific for one or more chains of the IL-2R, such as the alpha-chain, for example daclizumab. In other particular embodiments the autoimmune disease is multiple sclerosis. In certain embodiments administration of interferon-beta is combined with administration of an antagonist of the IL-2R to provide significant clinical improvement in a subject with an autoimmune disease.

Abstract: The invention is directed to compounds having the formula: wherein: Ar, r, n, X, R2-3 and R5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.

Abstract: A series of quinoline and quinoxaline derivatives, substituted by a fused bicyclic pyridine or pyrimidine moiety attached via an alkylene chain optionally linked to a heteroatom, being selective inhibitors of P13 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.

Abstract: A fluid heating system may be installed for residential and commercial use, and may deliver fluid at consistent high temperatures for cooking, sterilizing tools or utensils, hot beverages and the like, without a limit on the number of consecutive discharges of fluid. The fluid heating system is installed with a tankless fluid heating that includes an inlet port, an outlet port, a drain port, at least one heat source connected with the inlet port, and a valve manifold connected to the at least one heat source, the drain port, and the outlet port. A temperature sensor is downstream of the at least one heat source and connected to the valve manifold. The valve manifold is operated so that an entire volume of a fluid discharge from the fluid heating system is delivered at a user-specified temperature (including near boiling fluid) on demand, for every demand occurring over a short period of time.

Abstract: An operating method for a jet mill plant, wherein superheated steam at low pressure is used as an operating medium for a jet mill and the steam, after the jet mill and separation of grinding stock, is circulated back again into the jet mill via a compressor for excess pressure and temperature increase in the circuit. Furthermore, a jet mill plant includes a jet mill designed to operate with superheated steam at low pressure, wherein a jet mill steam discharge line, a compressor and a jet mill steam supply line form together with the jet mill a circuit for steam, so that steam is conveyed from the jet mill back again into the jet mill via the compressor for excess pressure and temperature increase in the circuit.

Abstract: A method for producing a printed product is provided in which a complete content of the printed product is printed sequentially in series on one or both sides along a paper web having a width based on a multiple of a width of a finished printed product. The method comprises cutting the paper web in a longitudinal direction to form at least one partial web having a width based on the width of the finished printed product; cutting the paper web in a direction crosswise to the longitudinal direction of the paper web to form a cut-off section for which a length is based on a multiple of a length of the finished printed product; and folding the partial web at least once in a crosswise direction in a location based on the length of the finished product.

Abstract: A method of controlling an automated transmission with positioning cylinders (6, 8, 20) controlled by shift valves or venting valves (10, 12, 16, 18, 22, 24). At least one cut-off valve (4) is positioned in front of the shift or venting valves and a control device controls the valves while pressure pipes, which follow the cut-off valve (4), are connected with one another following the cut-off valve (4). Due to the fact that the cut-off valve (4), for reasons of design simplicity and cost, is generally designed as a simple 2/2 way valve which only allows pressure increase but not pressure reduction, the method provides control of the shift valves or ventilation or venting valves (16, 18), of a non activated positioning cylinder (8), so that the pressure pipe system is connected with an outflow pipe (14) for a pressure reduction in the pressure pipe system (30, 32, 34).

Abstract: A method of controlling an automated transmission for motor vehicles with one or several pressure activated positioning cylinders (6, 8, 20), via the assigned shift valves (10, 12), at least one main cut-off valve (4) which is positioned prior to the shift valves, and a control device for controlling the shift and main cut-off valves. The pressure requests, for the shifting, are determined and the respective main cut-off valves are triggered depending on the determined pressure requests. To enable a variable match of the supply pressure during transmission shifts, respective optimized pressures or pressure patterns are determined for certain shift scenarios which, for instance, consider a mass to be synchronized, the existence of a tooth-on-tooth position, or the like. Through this method, for instance, the load on shift elements, the shift timing, and the shift noise can be positively influenced.

Abstract: A plant for the generation of methanol and for providing output power, preferably in the form of heat and/or electric energy. The plant comprises: (1) a water electrolysis facility which can be supplied by electric energy and water and which is designed in order to produce hydrogen gas and oxygen gas. The water electrolysis facility comprises a hydrogen gas outlet and an oxygen gas outlet; (2) a thermal engine with at least one combustion chamber designed for maintaining an oxygen-based combustion process in order to provide output power.

Abstract: A report analyzing system (1) is described. A text processing unit (2) analyzes a text portion (13, 23, 45) of a report. The text portion is in a natural language. The processing unit identifies a concept (41, 42, 43, 44) in the text portion, to obtain a set of identified concepts. A concept ranking unit (3) ranks the concepts (41, 42, 43, 44) of the set of identified concepts based on a ranking criterion, to obtain a ranking. A concept selector (4) selects at least one concept of the set of identified concepts based on the ranking, to obtain at least one selected concept. An associating unit (5) associates a visual representation (31, 32, 33, 34) with the report based on the at least one selected concept. The selected concept may belong to an ontology, e.g. a medical ontology.

Abstract: The invention relates to a process for enriching an iron mineral from a silicate containing iron ore by inverse flotation comprising the addition of a collector or collector composition comprising at least one of the compounds of formulae RO—X—NH2 (Ia); RO—X—NH3+Y? (Ib); RO—X—NH—Z—NH2 (IIa); and RO—X—NH—Z—NH3+Y? (IIb), in which X is a linear or branched aliphatic alkylene group containing 2 to 6 carbon atoms; Z is a linear or branched aliphatic alkylene group containing 2 to 6 carbon atoms; Y? is an anion; and R is an aliphatic group of the formula (I) C5H11CH(C3H7)CH2— (I) wherein the C5H11 moeity of the aliphatic group of the formula (I) comprises 70 to 99% by weight n-C5H11—, and 1 to 30% by weight C2H5CH(CH3)CH2— and/or CH3CH(CH3)CH2CH2—.

Abstract: The disclosure provides novel molecules related to growth and differentiation factor 8 (GDF8), in particular epitopes specific to GDF8 and other specific antagonists of GDF8 in particular anti GDF8 antibodies or antigen binding protein or fragment thereof which may inhibit GDF8 activity and signal in vitro and/or in vivo. The disclosure also provides for an immunoassay used to detect and quantitate GDF8. The disclosure also provides methods for diagnosing, preventing, ameliorating, and treating GDF8 associated disorders, e.g., degenerative orders of muscle, bone, and insulin metabolism. Finally, the disclosure provides pharmaceuticals for the treatment of such disorders by using the antibodies, polypeptides, polynucleotides, and vectors of the invention.

Abstract: The present invention relates to a process for producing N-alkyl-N-trialkylsilylamides from trialkylsilylhalides and N-alkylamides in the presence of a base and in the absence of a solvent.

Abstract: The invention is directed to compounds having the formula: wherein: Ar, r, Y, Z, Q, W, X, and R5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.

Abstract: The invention relates to an LED lamp comprising at least one LED as the luminaire, a ceramic base and a ceramic supporting body, arranged on the base and having a supporting surface for accommodating the LEDs, and further comprising a light-permeable lampshade which is fixed on the supporting body and put on the supporting surface, sintered metalized sections, which form a circuit board, being arranged on the supporting surface for the LEDs to be soldered to and optionally for applying a corresponding circuit thereto. In order for the light emitted by the LEDs to be influenced and guided by simple means, the lampshade has a cupola, dome or bonnet design and consists of glass or plastic.